5,610 research outputs found
Observation of single-diffractive production with CMS: a feasibility study
We present a study of single-diffractive -boson production in collisions at ~TeV, with including a boson, with the CMS detector. We discuss the feasibility of observing this process with an integrated effective luminosity for single interactions of 100~pb.We present a study of single-diffractive -boson production in collisions at TeV, with including a boson, with the CMS detector. We discuss the feasibility of observing this process with an integrated effective luminosity for single interactions of 100 pb
Corn cob lightweight concrete for non-structural applications
A lightweight concrete using granulated corn cob (without corn) as an aggregate is proposed in this
research work. Taking into account that corn cob, after extracting the corn, is generally considered an
agricultural waste, an interesting economic and sustainable benefit may result by using it as a building
material. Therefore, it can be an alternative sustainable lightweight aggregate solution in comparison
to the most currently applied ones such as expanded clay, particles of cork, particles of expanded polystyrene
(EPS), among others. The density, the compressive strength and the thermal insulation properties
of a corn cob concrete were experimentally quantified. An expanded clay concrete was also studied as
reference. The main results obtained are presented and discussed showing that the proposed corn cob
concrete may have the adequate material properties required for a lightweight concrete for non-structural
application purposes
Dynamics of bovine intramammary infections due to coagulase-negative staphylococci on four farms
The objectives of this study were to compare the impact of different coagulase-negative species (CNS) on udder health measured in terms of individual quarter milk somatic cell count (SCC) and duration of intramammary infection, and to get some insight into most likely routes of infection for different CNS species. This longitudinal observational study was performed on four farms that were sampled at 4-week intervals for a total of 12 visits each. Quarters infected with CNS were followed through time with milk samples being submitted for bacteriological culture and SCC determination. PCR amplification of the internal transcribed spacer region and sequencing of the sodA and rpoB genes were used for species allocation. Pulsed-field gel electrophoresis (PFGE) was performed to assess strain identity. The percentage of quarters affected per farm varied between 6 and 35%, with the most frequently isolated CNS species being Staphylococcus epidermidis, followed by Staph. simulans, Staph. chromogenes and Staph. haemolyticus. It was possible to follow 111 intramammary infections due to CNS through time. Duration of infection had a mean of 188 d and was not significantly different between CNS species. Geometric mean quarter SCC overall was 132 000 cells/ml and was also not significantly different between CNS species. Despite the possibility of a different epidemiology of infection, the impact in terms of udder health seems to be similar for different CNS species
Camada de regularização com agregado de granulado de caroço da espiga de milho
Um conjunto de construções antigas localizadas na região de Trás-os-Montes e
Alto Douro, Portugal, apresentam caroços de espiga de milho incorporados na camada de
enchimento de paredes exteriores de tabique. Esta descoberta tem vindo a estimular o
estudo do potencial da aplicação na construção civil deste resíduo agrícola. Um trabalho
de investigação preliminar permitiu concluir que este produto natural apresenta uma
microestrutura e uma condutibilidade térmica que lhe conferem um interesse de aplicação
no contexto do isolamento térmico. Este trabalho de investigação está centrado no estudo
do potencial da aplicação de granulado de caroço de espiga de milho como agregado para
argamassa ou betão leve de camada de regularização / enchimento. Para o efeito, um
trabalho experimental foi desenvolvido de forma a aferir algumas propriedades físicas,
mecânicas e de comportamento térmico deste material compósito. Amostras com
agregado de argila expandida também foram fabricadas e ensaiadas de forma a
funcionarem como referência. Com este trabalho de investigação pretende-se contribuir
para uma construção mais sustentável e amiga do ambiente
Silk bilayer scaffolds can induce fast integration with subchondral bone and support cartilage repair
Publicado em : J Tissue Eng Regen Med 2014; 8 (Suppl. 1)Introduction: Osteochondral defect (OCD) regeneration presents major
challenges in orthopedics. Since healing of cartilage and bone should
be simultaneously considered, ideal scaffolds should be those that can
mimic both tissues properties. In this study, bilayered silk and silk-nano
calcium phosphate (Silk/Silk-NanoCaP) scaffolds with tailored
mechanical properties were developed for OCD tissue engineering
application.
Materials and methods: Aqueous silk solution (16%) was prepared.1
Nano calcium phosphate particles (16%) were synthesized in the silk
solution (Silk-NanoCaP).2 The bony layer was prepared by addition of
NaCl particles (500–1000 lm) into the Silk-NanoCaP suspension. After
drying for 2 days and salt-leaching overnight, silk solution was added
on top of the bony layer using the same procedure to produce the chondral
layer. The !nal scaffolds were evaluated through in vitro culture of
rabbit bone marrow stromal cells (RBMSCs) for 2 weeks, and in vivo
implantation in a rabbit knee OCD for 4 weeks.
Results: The RBMSCs cultured in the scaffolds presented increasing
viability from day 1 to day 7 by MTS assay. Good adhesion and migration
of the RBMSCs in the scaffolds were achieved, as observed under
the scanning electron microscope. Cell proliferation was observed from
day 7 to day 14 as determined by DNA quanti!cation. The bony layer
induced higher alkaline phosphatase level as compared to the chondral
layer, in osteogenic condition. Histological analysis (H&E) showed that
the bilayered scaffolds integrated well with the host tissue, after
4 weeks of implantation in a critical size OC defect (Fig. 1). Abundant
new bone formation was detected in the Silk-NanoCaP layer. Cartilage
regeneration occurred in the silk layer.
Discussion and conclusions: The bilayered scaffolds favored the attachment,
proliferation, and differentiation of RBMSCs. The bony layer of
the bilayered scaffolds possessed osteoconductive properties. The bilayered
scaffolds were biocompatible in vitro and in vivo. These scaffolds
also induced both subchondral bone regeneration and supported cartilage
regeneration, thus showing great promise in OCD regeneration.
Acknowledgments: The authors thank FCT projects Tissue2Tissue and
OsteoCart, and the FP7 Programme POLARIS. Yan LP was awarded a
FCT PhD scholarship. Investigador FCT program (IF/00423/2012) and
(IF/00411/2013) are also greatly acknowledged.
Disclosure: The authors declare that there is no con"ict of interest
Oxitocina endovenosa na profilaxia activa da hemorragia pós-parto em cesariana: perspectiva anestésica
Após o esvaziamento uterino e expulsão da placenta a vasoconstrição produzida pela contracção uterina constitui o principal mecanismo de hemostase. A oxitocina é um peptídeo natural comercializado sob a forma sintética (Syntocinon®), actua por estimulação das contracções uterinas e é utilizada no terceiro estadio do trabalho de parto para a profilaxia da hemorragia pós-parto. Os autores procedem à revisão dos respectivos mecanismos de acção, farmacocinética, farmacodinâmica, efeitos adversos e de questões relacionadas com os regimes terapêuticos normalmente praticado
PHYSIOLOGICAL RESPONSES OF HOLSTEIN COW’S FACE TO RESOURCE OF FAN IN FREE-STALL
Este estudo teve como objetivo avaliar a influência do recurso de ventilação sobre a fisiologia de vacas Holandesas alojadas em free-stall, durante o verão do sudeste brasileiro. Foram utilizadas 20 vacas Holandesas submetidas a dois tratamentos: controle e ventilação. Os parâmetros ambientais registrados foram temperatura e umidade relativa do ar e temperatura de globo negro. As variáveis fisiológicas avaliadas foram temperatura retal e frequência respiratória. Para obtenção das estatísticas descritivas utilizou-se a metodologia de quadrados mínimos. Apesar das diferenças estatísticas obtidas para as variáveis fisiológicas, as mesmas não foram biologicamente efetivas e indicaram que os animais se encontravam em conforto térmico
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