EFFECTS OF DIFFERENT RETAIL PACKAGING MATERIALS ON THE SHELFLIFE OF DEHUSKED FOXTAIL MILLET

Millets are in the family of cereals grown globally with differential importance across continents and within regions of the world. Cereals are staple foods for a large proportion of the world population. The present investigation was carried out to find out the effect of different retail packaging material on the shelf-life of dehusked foxtail millet. The foxtail millet was procured at local Raichur market. Physical properties of dehusked foxtail millet viz., Particle density, Bulk density, Angle of repose, Coefficient of internal friction, Coefficient of external friction, Length, Breadth, Thickness, size and Spherecity were found to be 1.34 g/cc , 0.87 g/cc, 27.26°, 0.34, 0.27, 2.02 mm, 1.28 mm, 1.12 mm, 1.43 mm and 70.78 % respectively. Biochemical properties of dehusked foxtail millet viz., fat, fibre, carbohydrate, ash, protein, moisture content were determined initially to be 5.68 %, 4.76 %, 64.77 %, 1.64 %, 13.80 % and 9.35 %, respectively and there was no insect infestation before storing the commodity. Three types of packaging materials were used for retail packaging (1 kg) namely polyethylene (PE), polypropylene (PP) and polyethylene terapthalate (PET). The dehusked foxtail millet packed in different packaging material was kept for storage studies for 6 months. Quality analysis and insect infestation were checked regularly at the interval of 1 month. Finally it was concluded that for retail packaging PET was found to be best, based on its improved quality parameters and minimized insect infestation and also to prevent the damages due to insects and nutrient losses

Primary pituitary tuberculosis

Tuberculosis is an infectious disease that involves any organ. However, the primary pituitary tuberculosis is an extremely rare disease. Intracranial tuberculomas account for 0.15-5% of intracranial space-occupying lesions, of which, pituitary as the primary site is unusual, and easily misdiagnosed as pituitary adenoma. In this setting, the late diagnosis can result in permanent endocrine dysfunction. We report the case of a 50-year-old woman who presented to the neurosurgery outpatient department with complaints of progressively increasing headache and diminished vision over the last year. On the clinical examination, the patient was conscious and oriented. The routine hematological and biochemical workup showed an increased erythrocyte sedimentation rate (ESR) and increased prolactin levels. The radiological working diagnosis was consistent with pituitary macroadenoma. No other radiological and/or clinical clue that could elicit the suspicion of pulmonary or extrapulmonary lesions of tuberculosis was found. The transsphenoidal endonasal tumor excision was done. The histopathology showed numerous epithelioid cell granulomas, Langhans giant cells along with scant necrosis. Ziehl Neelsen staining demonstrated acid-fast bacilli, and the final diagnosis of pituitary tuberculoma was made. We report this rare case of pituitary lesion that may be included in the differential diagnosis of sellar lesions to avoid unnecessary surgical interventions, especially in regions where the disease is endemic

EFFECTS OF INTRATHECAL MIDAZOLAM IN SPINAL ANAESTHESIA: A PROSPECTIVE DOUBLE BLINDED CASE CONTROL STUDY

Background: Increasing the duration of action and maximizing postoperative analgesia has always been a domain of interest in spinal blocks. Many adjuvants have been tried along with local anaesthetic agent to achieve the same. The following study was conducted to compare sensory and motor characteristics with 2mg midazolam in subarachnoid block. Aim: To evaluate the efficacy and analgesic effect of the mixture of 2 mg midazolam and 15 mg (3 ml) hyperbaric bupivacaine as compared to bupivacaine alone in patients undergoing infra-umbilical surgery under spinal block. Material and Methods: In this observational prospective case control study 100 patients (ASA class I and II), aged 18 to 55 years, undergoing elective infra-umbilical surgeries under spinal block were randomly divided into Group I- patients were administered 0.5% hyperbaric Bupivacaine (3 ml) + 0.9% Normal saline (0.4 ml) intrathecally and Group 2- patients were administered 0.5% hyperbaric Bupivacaine (3 ml) + 2mg preservative free Midazolam (0.4 ml) intrathecally. The onset and duration of sensory and motor block, hemodynamic variables, and side effects during the surgery and recovery were compared among the groups. Results: 2mg of preservative free midazolam used as an adjuvant to bupivacaine intrathecally reduces onset time of sensory and motor blockade, also time taken to reach T-10. It also increases time taken for two segmental recession and mean duration of analgesia. Conclusion: It can be inferred that Inj. Midazolam 2 mg in combination with Inj. bupivacaine  0.5% hyperbaric can be safely administered  intrathecally for better postoperative analgesia. KEYWORDS: Intrathecal Midazolam; Post-operative Analgesia; Bupivacaine; Spinal Anesthesia

EFFECTS OF INTRATHECAL MIDAZOLAM IN SPINAL ANAESTHESIA: A PROSPECTIVE DOUBLE BLINDED CASE CONTROL STUDY

Background: Increasing the duration of action and maximizing postoperative analgesia has always been a domain of interest in spinal blocks. Many adjuvants have been tried along with local anaesthetic agent to achieve the same. The following study was conducted to compare sensory and motor characteristics with 2mg midazolam in subarachnoid block. Aim: To evaluate the efficacy and analgesic effect of the mixture of 2 mg midazolam and 15 mg (3 ml) hyperbaric bupivacaine as compared to bupivacaine alone in patients undergoing infra-umbilical surgery under spinal block. Material and Methods: In this observational prospective case control study 100 patients (ASA class I and II), aged 18 to 55 years, undergoing elective infra-umbilical surgeries under spinal block were randomly divided into Group I- patients were administered 0.5% hyperbaric Bupivacaine (3 ml) + 0.9% Normal saline (0.4 ml) intrathecally and Group 2- patients were administered 0.5% hyperbaric Bupivacaine (3 ml) + 2mg preservative free Midazolam (0.4 ml) intrathecally. The onset and duration of sensory and motor block, hemodynamic variables, and side effects during the surgery and recovery were compared among the groups. Results: 2mg of preservative free midazolam used as an adjuvant to bupivacaine intrathecally reduces onset time of sensory and motor blockade, also time taken to reach T-10. It also increases time taken for two segmental recession and mean duration of analgesia. Conclusion: It can be inferred that Inj. Midazolam 2 mg in combination with Inj. bupivacaine  0.5% hyperbaric can be safely administered  intrathecally for better postoperative analgesia. KEYWORDS: Intrathecal Midazolam; Post-operative Analgesia; Bupivacaine; Spinal Anesthesia

Radial artery pseudoaneurysm (RAP) following transradial intervention — an extremely rare complication successfully managed by surgery: case report

The transradial access for diagnostic and therapeutic purpose is becoming increasingly popular, mainly because of its lack of complications. Radial artery pseudoaneurysm (RAP) is an extremely rare complication, so many of its clinical features are unknown and treatment is not systematic. Therapeutic options are conservative management, ultrasound-guided compression, thrombin injection and surgical intervention. Here, we report a 43-year old female who underwent transradial percutaneous angioplasty of left anterior descending artery. During cannulation of her radial artery, multiple puncture attempts were done. Upon removal of the transra¬dial compression band (TR Band), forearm ecchymosis and small hematoma were noted with mild pain. Tight compression bandage was applied but on the following day, she had complaints of increasing right forearm pain and tenderness. Physical evaluation revealed increased swelling of the right forearm and an ultrasound of the right forearm demonstrated a RAP of the right radial artery measuring up to 3.9x1.9 cm with 3.4 mm neck. Tight compression bandage was further prolonged following ultrasound compression with vascular probe which failed to alleviate her complaints. Following failure of conservative therapy and in lieu of her symptoms, surgical exploration, clot removal and successful repair was done

Pierwotna przezskórma interwencja wieńcowa za pomocą cewnika diagnostycznego typu Tiger w przypadku nietypowego odejścia gałęzi pnia lewej tętnicy wieńcowej

The use of smaller catheters for diagnostic and intervention purpose is becoming increasingly popular due to the shift towards transradial catheterisation. The use of smaller catheters permits smaller arterial punctures, which translates into early mobilisation and discharge, as it may obviate the need for closure devices, lesser contrast volume use, potential nephrotoxicity and decreased morbidity. Here, we report a case, where standard 5 F Tiger diagnostic catheters (Terumo Radifocus Optitorque, Japan) was used for primary percutaneous coronary intervention of left circumflex artery with abnormal take-off of the left main

MemSPICE: Automated Simulation and Energy Estimation Framework for MAGIC-Based Logic-in-Memory

Existing logic-in-memory (LiM) research is limited to generating mappings and micro-operations. In this paper, we present~\emph{MemSPICE}, a novel framework that addresses this gap by automatically generating both the netlist and testbench needed to evaluate the LiM on a memristive crossbar. MemSPICE goes beyond conventional approaches by providing energy estimation scripts to calculate the precise energy consumption of the testbench at the SPICE level. We propose an automated framework that utilizes the mapping obtained from the SIMPLER tool to perform accurate energy estimation through SPICE simulations. To the best of our knowledge, no existing framework is capable of generating a SPICE netlist from a hardware description language. By offering a comprehensive solution for SPICE-based netlist generation, testbench creation, and accurate energy estimation, MemSPICE empowers researchers and engineers working on memristor-based LiM to enhance their understanding and optimization of energy usage in these systems. Finally, we tested the circuits from the ISCAS'85 benchmark on MemSPICE and conducted a detailed energy analysis.Comment: Accepted in ASP-DAC 202

Acute dislocation of fully deployed stent after use of non-compliant balloon: an enigma

Stent embolism is an established but rare complication of percutaneous coronary intervention, usually encountered when an undeployed stent unintentionally dislocates from the balloon. Published literature regarding incidence or clinical outcomes of embolism of fully deployed coronary stents is sparse. Here we report an unusual case of a 41-year-old male who had dislocation of a fully deployed stent into the distal part of left anterior descending artery following post dilatation by non-compliant balloon during percutaneous coronary intervention

Ektopowe, wysokie odejście prawej tętnicy wieńcowej — problemy techniczne w trakcie przezskórnej rewaskularyzacji wieńcowej

Anomalies of the coronary arteries are reported in 1–2% of patients who undergo a diagnostic angiogram. An ectopic origin of the right coronary artery from the opposite sinus is one of these anomalies, and while most are benign, at times it may be malignant. We report the case of a 43-year-old female who underwent primary percutaneous coronary intervention for acute inferior wall myocardial infarction where an ectopically arising right coronary artery (RCA) with abnormally high take-off was the culprit. We describe the various technical challenges faced during intervention, from cannulation to tracking of hardware. The RCA was cannulated using the floating wire technique and revascularised by the deployment of a 3.5 × 33 mm Xience Prime drug-eluting stent (Abbott Vascular, Santa Clara, CA, USA). In such a scenario where a conventional technique fails and where door-to-balloon time must be kept as short as possible, a little improvisation should resolve the problem.Anomalie tętnic wieńcowych występują u 1–2% chorych poddawanych diagnostycznej angiografii. Jedną z tych anomaliijest ektopowe odejście prawej tętnicy wieńcowej z przeciwległej zatoki. Choć większość anomalii tętnic wieńcowych jestłagodna, to niektóre z nich mogą powodować poważne następstwa.Przedstawiono przypadek 43-letniej kobiety poddanej pierwotnej przezskórnej angioplastyce wieńcowej z powodu ostregozawału ściany dolnej spowodowanego niedrożnością ektopowej prawej tętnicy wieńcowej (RCA) o nietypowo wysokimodejściu. Autorzy opisali różne problemy techniczne w trakcie zabiegu — od kaniulacji do wprowadzania urządzeń. KaniulacjęRCA przeprowadzono techniką floating wire, a rewaskularyzację uzyskano przez umieszczenie stentu 3.5 × 33 mmuwalniającego lek Xience Prime (Abbott Vascular, Santa Clara, CA, Stany Zjednoczone).W sytuacji, gdy konwencjonalna technika zawodzi, a czas od pierwszego kontaktu z personelem medycznym do rozpoczęciazabiegu (door-to-balloon) musi być jak najkrótszy, w rozwiązaniu problemu pomocna jest mała improwizacja

Skuteczne usunięcie przemieszczonego prowadnika z końcówką w kształcie „J” za pomocą samodzielnie skonstruowanej pętli u 75-letniego pacjenta — bezpieczna i dostępna metoda

Since the first report of percutaneous retrieval of intravascular foreign body in 1964, it has been accepted as a favourite approach for intravascular foreign body removal. Snares, biopsy forceps, dormia basket or tip deflecting wires are available in the armamentarium for this approach. Herein, we report percutaneous retrieval of a dislodged J-tip guide-wire by self-constructed snare. A patient was a 75-year-old woman who was admitted with capture failure following post pacemaker implantation. J-tip guide-wire was inadvertently left in her inferior vena cava during temporary pacemaker insertion. The guide wire was approached through right subclavian vein by a self-constructed snare and it was removed without any complications. Use of snares for intravascular foreign body removal is frequently reported and has been successful with low complication rates; also, the low cost of such snares makes it safe and economical.Od publikacji pierwszego doniesienia o przezskórnym usunięciu śródnaczyniowego ciała obcego w 1964 roku metoda ta jest najczęściej wybieraną techniką w przypadku śródnaczyniowej lokalizacji ciała obcego. Dostępne instrumentarium do takich zabiegów obejmują pętle, kleszczyki biopsyjne, koszyki typu dormia oraz prowadniki z giętką końcówką. W niniejszej pracy opisano przezskórne usunięcie przemieszczonego prowadnika z końcówką w kształcie „J” za pomocą pętli własnej konstrukcji. Kobieta w wieku 75 lat została przyjęta do placówki medycznej po nieudanej próbie usunięcia ciała obcego pozostałego po wszczepieniu stymulatora serca. Podczas wprowadzania czasowego stymulatora przypadkowo pozostawiono prowadnik z końcówką w kształcie „J” w żyle głównej dolnej pacjentki. Prowadnik uchwycono za pomocą pętli własnej konstrukcji wprowadzonej przez prawą tętnicę podobojczykową, a następnie wydobyto bez powikłań. Dostępnych jest wiele publikacji opisujących wykorzystanie pętli do usuwania śródnaczyniowych ciał obcych jako metody skutecznej i cechującej się niskim odsetkiem powikłań. Niskie koszty tego rodzaju pętli sprawiają, że metoda ta jest nie tylko bezpieczna, ale i ekonomiczna