1,703 research outputs found
Experimental observation of two-dimensional fluctuation magnetization in the vicinity of T_c for low values of the magnetic field in deoxygenated YBa_2Cu_3O_{7-x}
We measured isofield magnetization curves as a function of temperature in two
single crystal of deoxygenated YBaCuO with T_c = 52 and 41.5 K. Isofield MvsT
were obtained for fields running from 0.05 to 4 kOe. The reversible region of
the magnetization curves was analyzed in terms of a scaling proposed by Prange,
but searching for the best exponent . The scaling analysis carried
out for each data sample set with =0.669, which corresponds to the
3D-xy exponent, did not produced a collapsing of curves when applied to MvsT
curves data obtained for the lowest fields. The resulting analysis for the Y123
crystal with T_c = 41.5 K, shows that lower field curves collapse over the
entire reversible region following the Prange's scaling with =1,
suggesting a two-dimensional behavior. It is shown that the same data obeying
the Prange's scaling with =1 for crystal with T_c = 41.5 K, as well
low field data for crystal with = 52 K, obey the known two-dimensional
scaling law obtained in the lowest-Landau-level approximation.Comment: 4 pages, 3 figure
Tailoring Three-Point Functions and Integrability II. Weak/strong coupling match
We compute three-point functions of single trace operators in planar N=4 SYM.
We consider the limit where one of the operators is much smaller than the other
two. We find a precise match between weak and strong coupling in the
Frolov-Tseytlin classical limit for a very general class of classical
solutions. To achieve this match we clarify the issue of back-reaction and
identify precisely which three-point functions are captured by a classical
computation.Comment: 36 pages. v2: figure added, references adde
Can the evolution of music be analyzed in a quantitative manner?
We propose a methodology to study music development by applying multivariate
statistics on composers characteristics. Seven representative composers were
considered in terms of eight main musical features. Grades were assigned to
each characteristic and their correlations were analyzed. A bootstrap method
was applied to simulate hundreds of artificial composers influenced by the
seven representatives chosen. Afterwards we quantify non-numeric relations like
dialectics, opposition and innovation. Composers differences on style and
technique were represented as geometrical distances in the feature space,
making it possible to quantify, for example, how much Bach and Stockhausen
differ from other composers or how much Beethoven influenced Brahms. In
addition, we compared the results with a prior investigation on philosophy.
Opposition, strong on philosophy, was not remarkable on music. Supporting an
observation already considered by music theorists, strong influences were
identified between composers by the quantification of dialectics, implying
inheritance and suggesting a stronger master-disciple evolution when compared
to the philosophy analysis.Comment: 8 pages, 6 figures, added references for sections 1 and 4.C, better
mathematical description on section 2. New values and interpretation, now
considering a bootstrap metho
A comparative study of high-field diamagnetic fluctuations in deoxygenated YBa2Cu3O(7-x) and polycrystalline (Bi-Pb)2Sr2Ca3O(10)
We studied three single crystals of YBa2Cu3O{7-x} with Tc= 62.5, 52, and 41
K, and a textured specimen of (Bi-Pb)2Sr2Ca2Cu3O10 with Tc=108 K, for H//c
axis. The reversible data were interpreted in terms of 2D lowest-Landau-level
fluctuation theory. The data were fit well by the 2D LLL expression for
magnetization obtained by Tesanovic etal., producing reasonable values of kappa
but larger values of dHc2/dT. Universality was studied by obtaining a
simultaneous scaling of Y123 data and Bi2223. An expression for the 2D x-axis
LLL scaling factor used to obtain the simultaneous scaling was extracted from
theory, and compared with the experimental values. The comparison between the
values of the x-axis produced a deviation of 40% which suggests that the
hypothesis of universality of the 2D-LLL fluctuations is not supported by the
studied samples. We finaly observe that Y123 magnetization data for
temperatures above obbey a universal scaling obtained for the diamagnetic
fluctuation magnetization from a theory considering non-local field effects.
The same scaling was not obbeyed by the corresponding magnetization calculated
from the two-dimensional lowest-Landau-level theory.Comment: 7 pages 5 figures, accept in Journ. Low Temp. Phy
Finite-gap equations for strings on AdS_3 x S^3 x T^4 with mixed 3-form flux
We study superstrings on AdS_3 x S^3 x T^4 supported by a combination of
Ramond-Ramond and Neveu-Schwarz-Neveu-Schwarz three form fluxes, and construct
a set of finite-gap equations that describe the classical string spectrum.
Using the recently proposed all-loop S-matrix we write down the all-loop Bethe
ansatz equations for the massive sector. In the thermodynamic limit the Bethe
ansatz reproduces the finite-gap equations. As part of this derivation we
propose expressions for the leading order dressing phases. These phases differ
from the well-known Arutyunov-Frolov-Staudacher phase that appears in the pure
Ramond-Ramond case. We also consider the one-loop quantization of the algebraic
curve and determine the one-loop corrections to the dressing phases. Finally we
consider some classical string solutions including finite size giant magnons
and circular strings.Comment: 44 pages, 3 figures. v2: references and a discussion about
perturbative results adde
Laser-Plasma Interactions Enabled by Emerging Technologies
An overview from the past and an outlook for the future of fundamental
laser-plasma interactions research enabled by emerging laser systems
The average kinetic energy density of Cooper pairs above in , , and
We have obtained isofield curves for the square root of the average kinetic
energy density of the superconducting state for three single crystals of
underdoped , an optimally doped single crystal of
, and Nb. These curves, determined from isofield
magnetization versus temperature measurements and the virial theorem of
superconductivity, probe the order parameter amplitude near the upper critical
field. The striking differences between the Nb and the high- curves
clearly indicate for the latter cases the presence of a unique superconducting
condensate below and above
The incidence of liver injury in Uyghur patients treated for TB in Xinjiang Uyghur autonomous region, China, and its association with hepatic enzyme polymorphisms nat2, cyp2e1, gstm1 and gstt1.
BACKGROUND AND OBJECTIVE: Of three first-line anti-tuberculosis (anti-TB) drugs, isoniazid is most commonly associated with hepatotoxicity. Differences in INH-induced toxicity have been attributed to genetic variability at several loci, NAT2, CYP2E1, GSTM1and GSTT1, that code for drug-metabolizing enzymes. This study evaluated whether the polymorphisms in these enzymes were associated with an increased risk of anti-TB drug-induced hepatitis in patients and could potentially be used to identify patients at risk of liver injury. METHODS AND DESIGN: In a cross-sectional study, 2244 tuberculosis patients were assessed two months after the start of treatment. Anti-TB drug-induced liver injury (ATLI) was defined as an ALT, AST or bilirubin value more than twice the upper limit of normal. NAT2, CYP2E1, GSTM1 and GSTT1 genotypes were determined using the PCR/ligase detection reaction assays. RESULTS: 2244 patients were evaluated, there were 89 cases of ATLI, a prevalence of 4% 9 patients (0.4%) had ALT levels more than 5 times the upper limit of normal. The prevalence of ATLI was greater among men than women, and there was a weak association with NAT2*5 genotypes, with ATLI more common among patients with the NAT2*5*CT genotype. The sensitivity of the CT genotype for identifying patients with ATLI was 42% and the positive predictive value 5.9%. CT ATLI was more common among slow acetylators (prevalence ratio 2.0 (95% CI 0.95,4.20) )compared to rapid acetylators. There was no evidence that ATLI was associated with CYP2E1 RsaIc1/c1genotype, CYP2E1 RsaIc1/c2 or c2/c2 genotypes, or GSTM1/GSTT1 null genotypes. CONCLUSIONS: In Xinjiang Uyghur TB patients, liver injury was associated with the genetic variant NAT2*5, however the genetic markers studied are unlikely to be useful for screening patients due to the low sensitivity and low positive predictive values for identifying persons at risk of liver injury
Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes
The guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models of disrupted CNP and GC-B indicate a potential role in growth hormone secretion. In the current study, we investigate the molecular and pharmacological properties of the CNP/GC-B system in somatotrope lineage cells. Primary rat pituitary and GH3 somatolactotropes expressed functional GC-A and GC-B receptors that had similar EC50 properties in terms of cGMP production. Interestingly, GC-B signaling underwent rapid homologous desensitization in a protein phosphatase 2A (PP2A)-dependent manner. Chronic exposure to either CNP or ANP caused a significant down-regulation of both GC-A- and GC-B-dependent cGMP accumulation in a ligand-specific manner. However, this down-regulation was not accompanied by alterations in the sub-cellular localization of these receptors. Heterologous desensitization of GC-B signaling occurred in GH3 cells following exposure to either sphingosine-1-phosphate or thyrotrophin-releasing hormone (TRH). This heterologous desensitization was protein kinase C (PKC)-dependent, as pre-treatment with GF109203X prevented the effect of TRH on CNP/GC-B signaling. Collectively, these data indicate common and distinct properties of particulate guanylyl cyclase receptors in somatotropes and reveal that independent mechanisms of homologous and heterologous desensitization occur involving either PP2A or PKC. Guanylyl cyclase receptors thus represent potential novel therapeutic targets for treating growth-hormone-associated disorders
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