Chemical Reaction in a steady MHD flow with radiation and thermal conductivity over a porous inclined surface

A steady two dimensional mixed convective hydromagnetic flow over an inclined porous surface has been considered. The governing boundary layer equations and boundary conditions are transformed by a scaling group of transformation and finally solved numerically by using Runge-Kutta fourth-fifth order numerical method with shooting technique. Effects of suction/ injection, porosity, thermal radiation, chemical reaction parameter, Schmidt number and Prandtl number on velocity temperature and concentration profile presented graphically and discussed in detail. It is observed that velocity increases while temperature and concentration decreases with increasing values of chemical reaction parameter. The values of physical quantities like skin friction coefficient, Nusselt number and Sherwood number are also tabulated with the variation of physical parameters. Keywords: Chemical reaction, mass transfer, MHD, radiation, porosity, inclined surfac

Statistical analysis and modeling for biomolecular structures

Most of the recent studies on biomolecules address their three dimensional structure since it is closely related to their functions in a biological system. Determination of structure of biomolecules can be done by using various methods, which rely on data from various experimental instruments or on computational approaches to previously obtained data or datasets. Single particle reconstruction using electron microscopic images of macromolecules has proven resource-wise to be useful and affordable for determining their molecular structure in increasing details. The main goal of this thesis is to contribute to the single particle reconstruction methodology, by adding a process of denoising in the analysis of the cryo-electron microscopic images. First, the denoising methods are briefly surveyed and their efficiencies for filtering cryo-electron microscopic images are evaluated. In this thesis, the focus has been set to information theoretic minimum description length (MDL) principle for coding efficiently the essential part of the signal. This approach can also be applied to reduce noise in signals and here it is used to develop a novel denoising method for cryo-electron microscopic images. An existing denoising method has been modified to suit the given problem in single particle reconstruction. In addition, a more general denoising method has been developed, discovering a novel way to find model class by using the MDL principle. This method was then thoroughly tested and compared with co-existing methods in order to evaluate the utility of denoising in single particle reconstruction. A secondary goal in the research for this thesis deals with studying protein oligomerisation, using computational approaches. The focus has been to recognize interacting residues in proteins for oligomerization and to model the interaction site for hantavirus N-protein. In order to unravel the interaction structure, the approach has been to understand the phenomenon of protein folding towards quaternary structure.reviewe

Simulation Based Analysis of Temperature Effect on Breakdown Voltage of Ion Implanted Co/n-Si Schottky Diode

In semiconductor devices, breakdown voltage variation with temperature is a very significant study, since the reliability and performance of semiconductor devices especially depends upon the temperature. In this paper, the influence of temperature on breakdown characteristic of Ion Implanted edge terminated Co/n-Si Schottky Diode formed on n-Si epitaxial layer has been investigated by using SILVACO TCAD. It is also reported that not only resistive area present in close proximity to the edges of boron ion implanted Schottky diode are responsible for improvement in breakdown voltage but also the formation of PN junction near the edges, affect the breakdown voltage to a significant amount. The dopant concentration of epitaxial layer is 1 × 1015/cm3. The variation in reverse breakdown characteristics as a junction of temperature in the range of 300-1000 K is presented in this paper. A comparative study of breakdown voltages of Ion Implanted and as-prepared Schottky diode is also presented. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/3026

Instabilities near ultrastrong coupling in microwave optomechanical cavity

With artificially engineered systems, it is now possible to realize the coherent interaction rate, which can become comparable to the mode frequencies, a regime known as ultrastrong coupling (USC). We experimentally realize a cavity-electromechanical device using a superconducting waveguide cavity and a mechanical resonator. In the presence of a strong pump, the mechanical-polaritons splitting can nearly reach 81% of the mechanical frequency, overwhelming all the dissipation rates. Approaching the USC limit, the steady-state response becomes unstable. We systematically measure the boundary of the unstable response while varying the pump parameters. The unstable dynamics display rich phases, such as self-induced oscillations, period-doubling bifurcation, period-tripling oscillations, and ultimately leading to the chaotic behavior. The experimental results and their theoretical modeling suggest the importance of residual nonlinear interaction terms in the weak-dissipative regime.Comment: 7 pages, 4 figures, and supplemental materia

Genome wide binding (ChIP-Seq) of murine Bapx1 and Sox9 proteins in vivo and in vitro

AbstractThis work pertains to GEO submission GSE36672, in vivo and in vitro genome wide binding (ChIP-Seq) of Bapx1/Nkx3.2 and Sox9 proteins. We have previously shown that data from a genome wide binding assay combined with transcriptional profiling is an insightful means to divulge the mechanisms directing cell type specification and the generation of tissues and subsequent organs [1]. Our earlier work identified the role of the DNA-binding homeodomain containing protein Bapx1/Nkx3.2 in midgestation murine embryos. Microarray analysis of EGFP-tagged cells (both wildtype and null) was integrated using ChIP-Seq analysis of Bapx1/Nkx3.2 and Sox9 DNA-binding proteins in living tissue

Design guidelines for thin diaphragm-based microsystems through comprehensive numerical and analytical studies

This paper presents comprehensive guidelines for the design and analysis of a thin diaphragm that is used in a variety of microsystems, including microphones and pressure sensors. It highlights the empirical relations that can be utilized for the design of thin diaphragm-based microsystems (TDMS). Design guidelines developed through a Finite Element Analysis (FEA) limit the iterative efforts to fabricate TDMS. These design guidelines are validated analytically, with the assumption that the material properties are isotropic, and the deviation from anisotropic material is calculated. In the FEA simulations, a large deflection theory is taken into account to incorporate nonlinearity, such that a critical dimensional ratio of /ℎ or 2/ℎ can be decided to have the linear response of a thin diaphragm. The observed differences of 12% in the deflection and 13% in the induced stresses from the analytical calculations are attributed to the anisotropic material consideration in the FEA model. It suggests that, up to a critical ratio (/ℎ or 2/ℎ ), the thin diaphragm shows a linear relationship with a high sensitivity. The study also presents a few empirical relations to finalize the geometrical parameters of the thin diaphragm in terms of its edge length or radius and thickness. Utilizing the critical ratio calculated in the static FEA analysis, the basic conventional geometries are considered for harmonic analyses to understand the frequency response of the thin diaphragms, which is a primary sensing element for microphone applications and many more. This work provides a solution to microelectromechanical system (MEMS) developers for reducing cost and time while conceptualizing TDMS designs