Fermentability of whole oat flour, PeriTec flour and bran by Lactobacillus plantarum

4 páginas, 2 tablas, 1 figuraWhole oat flour obtained by hammer milling was fermented with Lactobacillus plantarum along with white flour and bran in order to compare the suitability of these substrates for the production of a probiotic beverage. The three substrates show a viable cell concentration at the end of fermentation above the minimum required in a probiotic product. The highest cell concentration was observed in white flour (9.16 Log10 CFU/mL) and the lowest in the bran sample (8.17 Log10 CFU/mL)Peer reviewe

Membrane-transferring regions of gp41 as targets for HIV-1 fusion inhibition and viral neutralization

12 páginas, 4 figurasThe fusogenic function of HIV-1 gp41 transmembrane Env subunit relies on two different kinds of structural elements: i) a collapsible ectodomain structure (the hairpin or six-helix bundle) that opens and closes, and ii) two membrane- transferring regions (MTRs), the fusion peptide (FP) and the membrane-proximal external region (MPER), which ensure coupling of hairpin closure to apposition and fusion of cell and viral membranes. The isolation of naturally produced short peptides and neutralizing IgG-s, that interact with FP and MPER, respectively, and block viral infection, suggests that these conserved regions might represent useful targets for clinical intervention. Furthermore, MTR-derived peptides have been shown to be membrane-active. Here, it is discussed the potential use of these molecules and how the analysis of their membrane activity in vitro could contribute to the development of HIV fusion inhibitors and effective immunogensThe authors wish to thank financial support obtained from Spanish MICINN (BIO2008- 00772) (JLN) and University of the Basque Country (GIU 06/42 and DIPE08/12) (NH and JLN).Peer reviewe

Менеджмент

Присвячується нашому вчителю - професору Саллі В.І. та академіку Амоші О.І. - мудрому наставнику і колезі.Навчальний посібник призначений для формування у майбутніх менеджерів управлінського мислення та системи спеціальних знань у галузі менеджменту, формування розуміння концептуальних основ системного управління організаціями, набуття умінь аналізу середовища діяльності організації, прийняття адекватних управлінських рішень

Проблемы и перспективы развития тепловой энергетики в России

Данная статья посвящена обзору экономических проблем и перспектив развития тепловой энергетики в России. Проведенное исследование показало - техническое оборудование тепловых станций морально устарело, что ведет к снижению технико-экономических показателей. Перспективы развития этой отрасли требуют хорошо скоординированных научно-технических усилий. Проблемы теплоэнергетики в стране, как никогда актуальны

Zero Bias Power Detector Circuits based on MoS2_2 Field Effect Transistors on Wafer-Scale Flexible Substrates

We demonstrate the design, fabrication, and characterization of wafer-scale, zero-bias power detectors based on two-dimensional MoS$_2$ field effect transistors (FETs). The MoS$_2$ FETs are fabricated using a wafer-scale process on 8 $\mu$m thick polyimide film, which in principle serves as flexible substrate. The performances of two CVD-MoS$_2$ sheets, grown with different processes and showing different thicknesses, are analyzed and compared from the single device fabrication and characterization steps to the circuit level. The power detector prototypes exploit the nonlinearity of the transistors above the cut-off frequency of the devices. The proposed detectors are designed employing a transistor model based on measurement results. The fabricated circuits operate in Ku-band between 12 and 18 GHz, with a demonstrated voltage responsivity of 45 V/W at 18 GHz in the case of monolayer MoS2 and 104 V/W at 16 GHz in the case of multilayer MoS$_2$, both achieved without applied DC bias. They are the best performing power detectors fabricated on flexible substrate reported to date. The measured dynamic range exceeds 30 dB outperforming other semiconductor technologies like silicon complementary metal oxide semiconductor (CMOS) circuits and GaAs Schottky diodes.Comment: 28 page

Разработка технологии сварки и контроль качества резервуара вертикального стального РВС-5000

Объектом исследования является разработка технологии сварки и контроль качества резервуара вертикального стального РВС-5000.В заключительном разделе "Социальная ответственность" произведено обоснование мер социальной ответственности предлагаемой технологии сварки и контроля качества резервуара вертикального стального РВС-5000. В заключении кратко отображен анализ результатов разработки предлагаемой технологии изготовления резервуара вертикального стального РВС-5000.The object of the research is the development of welding technology and quality control of a vertical steel tank RVS-5000.In the final section “Social Responsibility”, the rationale for the social responsibility measures of the proposed welding technology and quality control of a vertical steel RVS-5000 tank was made. In conclusion, an analysis of the results of the development of the proposed technology for the manufacture of a vertical steel RVS-5000 reservoir is briefly displayed