Measurements of complex permittivity of microwave substrates in the 20 to 300 K temperature range from 26.5 to 40.0 GHz

A knowledge of the dielectric properties of microwave substrates at low temperatures is useful in the design of superconducting microwave circuits. Results are reported for a study of the complex permittivity of sapphire (Al2O3), magnesium oxide (MgO), silicon oxide (SiO2), lanthanum aluminate (LaAlO3), and zirconium oxide (ZrO2), in the 20 to 300 Kelvin temperature range, at frequencies from 26.5 to 40.0 GHz. The values of the real and imaginary parts of the complex permittivity were obtained from the scattering parameters, which were measured using a HP-8510 automatic network analyzer. For these measurements, the samples were mounted on the cold head of a helium gas closed cycle refrigerator, in a specially designed vacuum chamber. An arrangement of wave guides, with mica windows, was used to connect the cooling system to the network analyzer. A decrease in the value of the real part of the complex permittivity of these substrates, with decreasing temperature, was observed. For MgO and Al2O3, the decrease from room temperature to 20 K was of 7 and 15 percent, respectively. For LaAlO3, it decreased by 14 percent, for ZrO2 by 15 percent, and for SiO2 by 2 percent, in the above mentioned temperature range

Protein coingestion with alcohol following strenuous exercise attenuates alcohol-induced intramyocellular apoptosis and inhibition of autophagy

Alcohol ingestion decreases postexercise rates of muscle protein synthesis, but the mechanism(s) (e.g., increased protein breakdown) underlying this observation is unknown. Autophagy is an intracellular “recycling” system required for homeostatic substrate and organelle turnover; its dysregulation may provoke apoptosis and lead to muscle atrophy. We investigated the acute effects of alcohol ingestion on autophagic cell signaling responses to a bout of concurrent (combined resistance- and endurance-based) exercise. In a randomized crossover design, eight physically active males completed three experimental trials of concurrent exercise with either postexercise ingestion of alcohol and carbohydrate (12 ± 2 standard drinks; ALC-CHO), energy-matched alcohol and protein (ALC-PRO), or protein (PRO) only. Muscle biopsies were taken at rest and 2 and 8 h postexercise. Select autophagy-related gene (Atg) proteins decreased compared with rest with ALC-CHO (P < 0.05) but not ALC-PRO. There were parallel increases (P < 0.05) in p62 and PINK1 commensurate with a reduction in BNIP3 content, indicating a diminished capacity for mitochondria-specific autophagy (mitophagy) when alcohol and carbohydrate were coingested. DNA fragmentation increased in both alcohol conditions (P < 0.05); however, nuclear AIF accumulation preceded this apoptotic response with ALC-CHO only (P < 0.05). In contrast, increases in the nuclear content of p53, TFEB, and PGC-1α in ALC-PRO were accompanied by markers of mitochondrial biogenesis at the transcriptional (Tfam, SCO2, and NRF-1) and translational (COX-IV, ATPAF1, and VDAC1) level (P < 0.05). We conclude that alcohol ingestion following exercise triggers apoptosis, whereas the anabolic properties of protein coingestion may stimulate mitochondrial biogenesis to protect cellular homeostasis

Ursinus College Alumni Journal, November 1953

President\u27s page • A new year opens at Ursinus with 675 students • Approximately 100 students attend summer sessions • Ursinus welcomes two new members to its faculty • Ursinus evening school opens its second year • From the desk of the registrar • Alumni activities • News from the local alumni groups • Philadelphia square dance • Washington, D.C. hears President Glassmoyer • York alumni see baby pictures • 22 new M.D. graduates serving internship • Have you earned a Ph.D.? • Annual Cub and Key meeting on November 7 • Old timers\u27 day • Permanent class officers meet with loyalty fund committee • Ursinus bears beat Haverford 13 to 7 • Hockey field dedicated to Effie Brant Evans, \u2718 • A big thanks to class workers • Have you seen the new alumni office? • Memo from the executive committee • Sports review • Ray Gurzynski reviews the 1953 football prospects • Coach Harry Spangler sees bright prospect for his courtmen • Doc Baker reviews his 1953 soccer squad • Preview of 1953 wrestling • Hockey belles look forward to successful season • Pre-session camp at Ursinus fits phys-edders for 1953 sports • Ursinus is proud of its faculty • News about ourselves • Engagements • Weddings • Births • Christmas luncheon set for December 5, 1953 • Alumni basketball game January 19 • Necrologyhttps://digitalcommons.ursinus.edu/alumnijournal/1048/thumbnail.jp

Ursinus College Alumni Journal, November 1955

Program for new dormitories underway • Business, the alumnus, and the cost of higher education • Campbell Soup Company establishes fund • James Hirst named to honor society • 18th annual performance announced of the Messiah • Attendance increases in the Ursinus College Evening School • Some notes from the Dean\u27s office • Registrar\u27s report on fall enrollment • Ursinus forum 1955-1956 • Max C. Putney \u2718 author of The Man of Galilee • South Jersey alumni honor Dr. McClure • Binder named Dean at Thiel College • Berks County alumni hold clam bake • Dr. Sherman A. Eger \u2725 describes new operation for high blood pressure • James J. Herron \u2732 elected vice-president of Dun & Bradstreet, Inc. • Alumni eligible for Fulbright scholarships • Ursinus Women\u27s Club • Committee to review alumni constitution • A Fulbrighter in Japan • 1955 Loyalty Fund report • Sick transit - or - She perks no more • Curtain Club presents The Madwoman of Chaillot • Class of \u2756 elects permanent alumni officers • Mrs. Snyder new preceptress at Duryea Hall • G. E. reports on its corporate alumnus program • Regional alumni groups plan student trip • Warren K. Hess \u2731 addresses state school directors • 51\u27ers quartet meet after four years • History art collection • Sports review: Soccer report; Facts about the coaching staff; Alumni varsity basketball game • News about ourselves • Weddings • Births • Necrologyhttps://digitalcommons.ursinus.edu/alumnijournal/1054/thumbnail.jp

Ursinus College Alumni Journal, March 1956

President\u27s page • Sigma Rho scholarship fund grows • Three Ursinus alumni honored at Founders\u27 Day ceremony • $1000 memorial donation from Ursinus Woman\u27s Club • Ford Foundation gives$191,400 to Ursinus College • Enrollment increases in Evening School • Notes from the Dean\u27s office • Ursinus presentation of Messiah recorded • From the Office of Admissions • Faculty corner • Philadelphia alumni to meet at Casa Conti • Plan now to return Alumni Day, June 2 • Spring banquet planned by Lehigh Valley • May 2nd, date for New York alumni • South Jersey alumni plan dinner-dance • Woman\u27s Club plans spring activities • Booster committee holds banquet for athletes • Ditter, Warden, Tredinnick, Assistant District Attorneys • Alumni invited to Varsity Club dinner • Dr. Gilbert Bayne \u2743 speaks to science societies • Isaac Norris of Norristown, PA • Alumni elections • Schoolmen\u27s Week teachers luncheon • Washington area alumni reorganize • Report of the loyalty fund campaign • Sports review: Football season 1955; Dave Burger named to All-American soccer team; Soccer season 1955; Wrestling; 1955 alumnae hockey; Heller and Dawkins excel in women\u27s hockey • News about ourselves • Births • Weddings • Necrologyhttps://digitalcommons.ursinus.edu/alumnijournal/1055/thumbnail.jp

Identification of Class I HLA T Cell Control Epitopes for West Nile Virus

The recent West Nile virus (WNV) outbreak in the United States underscores the importance of understanding human immune responses to this pathogen. Via the presentation of viral peptide ligands at the cell surface, class I HLA mediate the T cell recognition and killing of WNV infected cells. At this time, there are two key unknowns in regards to understanding protective T cell immunity: 1) the number of viral ligands presented by the HLA of infected cells, and 2) the distribution of T cell responses to these available HLA/viral complexes. Here, comparative mass spectroscopy was applied to determine the number of WNV peptides presented by the HLA-A*11:01 of infected cells after which T cell responses to these HLA/WNV complexes were assessed. Six viral peptides derived from capsid, NS3, NS4b, and NS5 were presented. When T cells from infected individuals were tested for reactivity to these six viral ligands, polyfunctional T cells were focused on the GTL9 WNV capsid peptide, ligands from NS3, NS4b, and NS5 were less immunogenic, and two ligands were largely inert, demonstrating that class I HLA reduce the WNV polyprotein to a handful of immune targets and that polyfunctional T cells recognize infections by zeroing in on particular HLA/WNV epitopes. Such dominant HLA/peptide epitopes are poised to drive the development of WNV vaccines that elicit protective T cells as well as providing key antigens for immunoassays that establish correlates of viral immunity. © 2013 Kaabinejadian et al

1961

My Ideal Course, Underwater, U.S.A. (page 1) From the Editor (3) Turf Management Club News (3) Quotes from 1961 Seniors (4) The United States Most Western Owned Golf Course: Armed Forces Golf Course, Guam (5) Turf Majors Participate in Horticultural Show (7) Picture - G.C.S.A Scholarships Awarded to Three Turf Seniors (8) Picture - Stockbridge - Majors in turf Management (9) Opportunity and Education (10) The Most Outstanding Turf Senior for the Year - 1961 (11) How We Prepare Our Greens Before Topdressing (12) An Inexpensive Cure for Weeds and Poa Annua (13) Watering (14) Picture - Honorary Members of the Turf Management Club (16) Picture - Graduates of Winter School for Turf Managers - 1961 (17) Welcome Speech by Narry Sperandio (A-1) Handle with Care by Dr. Ellsworth H. Wheeler (A-2) Current Ideas on Green Construction - Panel Discussion (A-4) Automatic Systems for Watering by Robert F. Harper (A-14) History of Golf Course Architecture by Geoffrey S. Cornish (A-22) Effect of Nutrition on Turf Diseases by Dr. Houston B. Couch Turf Disease Control and Use of Fungicides by Dr. R. J. Lukens Trees and Tree Care by Gordon S. King (A-38) Arsenical Toxicity by Dr. C. R. Skogley (A-41) Soil Reaction to Arsenical Compounds by Joseph E. Steckel Brush Control For the Golf Course by Dr. William I. Boyd (A-51) Massachusetts Highway Herbicide Program by Joseph L. Beasley (A-54) General Turf (Alternate Session): Observations on Highway Turf Establishment & Maintenance by E.F. Button (A-62) Pre-emerge Chemicals for the Control of Crabgrass by Dr. John R. Havis, John M. Zak & Joseph Troll (A-70) Root Growth of Turf Grasses as Affected by Different heights of Cut and Nutrient Levels by Evangel J. Bredakis (A-71) The Use of Sod by Daniel Pellegrino (A-72

GB virus-C – a virus without a disease: We cannot give it chronic fatigue syndrome

BACKGROUND: Chronic fatigue syndrome (CFS) is an illness in search of an infectious etiology. GB virus-C (GBV-C) virus is a flavivirus with cell tropism and host defense induction qualities compatible with a role in producing the syndrome. The GBV-C genome is detectable in 4% of the population and 12% of the population is seropositive. The present study evaluated the association between infection with GBV and CFS. METHODS: We used a commercial EIA to detect antibodies against the GBV-C E2 protein and a quantitative real-time RT-PCR assay to detect active GBV-C infection. Sera were from a case control study of CFS in Atlanta, Georgia. The Fisher's exact two-tailed test was used for statistical analysis. RESULTS: Two of 12 CFS patients and one of 21 controls were seropositive for prior GBV-C infection and one control had viral RNA detected, indicating active infection. The results are not statistically different. CONCLUSION: We found no evidence that active or past infection with GBV is associated with CFS