From Statement to Purpose: An Interview with Bill Siemering

This article is an interview between RadioDoc Review Editor Neil Verma and Bill Siemering, founding Director of Programming at National Public Radio and lifelong proponent of public radio. Siemering and Verma discuss Siemering\u27s role at the founding of NPR, his earlymcareer in Wisconsin, WHYY Philadelphia, WBFO and KCCM, as well as his enduring work in community radio development in Africa

The Arts of Amnesia: The Case for Audio Drama, Part One

This article examines what the relationship between audio drama and radio drama might illuminate about both forms. Drawing on some 40 podcasts and other audio forms that take a serial structure, I explore the rise of audio drama podcasts since 2015 and situate them in both a more recent historical context since the late 1990s and in a broader history stretching back to the first Golden Age of radio. By listening closely to key works on Serendipity, Homecoming and other podcasts, I argue that contemporary audio has profound potential to change both how we listen and how we relate to the sound media of the past. This is Part One of a two-part series

Commencement of the Class of 2016

It’s amazing how fast three years passes. And in the end, IMSA is so much more than just a building. Others may never truly understand what it means to be a part of this community, but we will know. Years from now, we’ll remember the thrill of Clash or the nostalgic warmth of Carnival. We’ll remember late nights spent laughing with best friends, and we’ll remember what it felt like to belong here. It’s true, IMSA gave us the building blocks for academic and professional success. But it also gave us each other. And as we stand here as a class for the last time, I thank IMSA for bringing us together. Class of 2016, never stop learning and growing. Never lose that drive or that passion, and never forget what you have gained from IMSA. As we move on to another chapter of our lives, we will continue to expand our brick-and-mortar walls. We will gain countless more chances, and we will learn countless more things. It is my hope that we, as a class, will continue to seek out new opportunities, and I hope that we continue to find better ways of cementing it all together. Yet no matter how far we go, part of us will always belong in a residence hall at 1500 Sullivan Road. And no matter how far apart we may end up, we can find comfort in knowing that we have built something beautiful together Heidi Dong, Student Council Presiden

Neurolymphomatosis mimicking neurosarcoidosis: a case report

<p>Abstract</p> <p>Introduction</p> <p>Both neurosarcoidosis and central nervous system lymphoma can be very difficult to diagnose. We describe the case of a patient in whom neurosarcoidosis was strongly suspected, but who was eventually found to have lymphoma. We believe the case to be of interest and practical value to neurologists, oncologists and internists with an interest in inflammatory diseases.</p> <p>Case presentation</p> <p>A diagnosis of neurosarcoidosis was considered in a 49-year-old Caucasian man on the basis of the following symptoms and indications: a cough, bilateral hilar lymphadenopathy confirmed by thoracic computed tomography, the development of an S1 radiculopathy, cerebrospinal fluid abnormalities (raised protein level), bilateral lung hilar and lachrymal gland uptake on a gallium scan, and erythema nodosum confirmed with skin biopsy. These were followed by the development of multiple cranial neuropathies, including seventh nerve palsy. Exhaustive further investigations yielded no evidence for an alternative diagnosis. Treatments with steroids, cyclophosphamide, intravenous immunoglobulin and finally infliximab were of no benefit. He eventually developed cutaneous nodules, a biopsy of which revealed lymphoma that proved resistant to therapy.</p> <p>Conclusion</p> <p>Constant diagnostic vigilance is required in disorders such as neurosarcoidosis.</p

From START to FINISH : the influence of osmotic stress on the cell cycle

Peer reviewedPublisher PD

Subanesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks

Acute treatment with subanesthetic ketamine, a non-competitive N-methyl-D-aspartic acid (NMDA) receptor antagonist, is widely utilized as a translational model for schizophrenia. However, how acute NMDA receptor blockade impacts on brain functioning at a systems level, to elicit translationally relevant symptomatology and behavioral deficits, has not yet been determined. Here, for the first time, we apply established and recently validated topological measures from network science to brain imaging data gained from ketamine-treated mice to elucidate how acute NMDA receptor blockade impacts on the properties of functional brain networks. We show that the effects of acute ketamine treatment on the global properties of these networks are divergent from those widely reported in schizophrenia. Where acute NMDA receptor blockade promotes hyperconnectivity in functional brain networks, pronounced dysconnectivity is found in schizophrenia. We also show that acute ketamine treatment increases the connectivity and importance of prefrontal and thalamic brain regions in brain networks, a finding also divergent to alterations seen in schizophrenia. In addition, we characterize how ketamine impacts on bipartite functional interactions between neural subsystems. A key feature includes the enhancement of prefrontal cortex (PFC)-neuromodulatory subsystem connectivity in ketamine-treated animals, a finding consistent with the known effects of ketamine on PFC neurotransmitter levels. Overall, our data suggest that, at a systems level, acute ketamine-induced alterations in brain network connectivity do not parallel those seen in chronic schizophrenia. Hence, the mechanisms through which acute ketamine treatment induces translationally relevant symptomatology may differ from those in chronic schizophrenia. Future effort should therefore be dedicated to resolve the conflicting observations between this putative translational model and schizophrenia

Proceedings of Abstracts Engineering and Computer Science Research Conference 2019

© 2019 The Author(s). This is an open-access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For further details please see https://creativecommons.org/licenses/by/4.0/. Note: Keynote: Fluorescence visualisation to evaluate effectiveness of personal protective equipment for infection control is © 2019 Crown copyright and so is licensed under the Open Government Licence v3.0. Under this licence users are permitted to copy, publish, distribute and transmit the Information; adapt the Information; exploit the Information commercially and non-commercially for example, by combining it with other Information, or by including it in your own product or application. Where you do any of the above you must acknowledge the source of the Information in your product or application by including or linking to any attribution statement specified by the Information Provider(s) and, where possible, provide a link to this licence: http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/This book is the record of abstracts submitted and accepted for presentation at the Inaugural Engineering and Computer Science Research Conference held 17th April 2019 at the University of Hertfordshire, Hatfield, UK. This conference is a local event aiming at bringing together the research students, staff and eminent external guests to celebrate Engineering and Computer Science Research at the University of Hertfordshire. The ECS Research Conference aims to showcase the broad landscape of research taking place in the School of Engineering and Computer Science. The 2019 conference was articulated around three topical cross-disciplinary themes: Make and Preserve the Future; Connect the People and Cities; and Protect and Care

Storage and Reemission of Heralded Telecommunication-Wavelength Photons Using a Crystal Waveguide

Large-scale fiber-based quantum networks will likely employ telecommunication-wavelength photons of around 1550 nm wavelength to exchange quantum information between remote nodes, and quantum memories, ideally operating at the same wavelength, that allow the transmission distances to be increased, as key elements of a quantum repeater. However, the development of a suitable memory remains an ongoing challenge. Here, we demonstrate the storage and reemission of single heralded 1532-nm-wavelength photons using a crystal waveguide. The photons are emitted from a photon-pair source based on spontaneous parametric down-conversion and the memory is based on an atomic frequency comb of 6 GHz bandwidth, prepared through persistent spectral-hole burning of the inhomogeneously broadened absorption line of a cryogenically cooled erbium-doped lithium niobate waveguide. Despite currently limited storage time and efficiency, this demonstration represents an important step toward quantum networks that operate in the telecommunication band and the development of integrated (on-chip) quantum technology using industry-standard crystals