134 research outputs found
Effect of Changing the Vocal Tract Shape on the Sound Production of the Recorder: An Experimental and Theoretical Study
Changing the vocal tract shape is one of the techniques which can be used by
the players of wind instruments to modify the quality of the sound. It has been
intensely studied in the case of reed instruments but has received only little
attention in the case of air-jet instruments. This paper presents a first study
focused on changes in the vocal tract shape in recorder playing techniques.
Measurements carried out with recorder players allow to identify techniques
involving changes of the mouth shape as well as consequences on the sound. A
second experiment performed in laboratory mimics the coupling with the vocal
tract on an artificial mouth. The phase of the transfer function between the
instrument and the mouth of the player is identified to be the relevant
parameter of the coupling. It is shown to have consequences on the spectral
content in terms of energy distribution among the even and odd harmonics, as
well as on the stability of the first two oscillating regimes. The results
gathered from the two experiments allow to develop a simplified model of sound
production including the effect of changing the vocal tract shape. It is based
on the modification of the jet instabilities due to the pulsating emerging jet.
Two kinds of instabilities, symmetric and anti-symmetric, with respect to the
stream axis, are controlled by the coupling with the vocal tract and the
acoustic oscillation within the pipe, respectively. The symmetry properties of
the flow are mapped on the temporal formulation of the source term, predicting
a change in the even / odd harmonics energy distribution. The predictions are
in qualitative agreement with the experimental observations
A Minimal Model of a Single-Reed Instrument Producing Quasi-Periodic Sounds
International audienceSingle-reed instruments can produce multiphonic sounds when they generate quasi-periodic oscillations. The aim of this article is to identify a minimal model of a single reed-instrument producing quasi-periodic oscillations. To better understand the influence of model parameters on the production of quasi-periodic regimes, the mapping between parameters and quasi-periodic regimes is explicitly identified using a support vector machine (SVM) classifier. SVMs enable the construction of boundaries between quasi-periodic and periodic regimes that are explicitly defined in terms of the parameters. Results and conclusions obtained from the numerical model are compared to published experiments related to the the production of quasi-periodic oscillations with an alto saxophone. This qualitative comparison highlights the influence of key parameters on the production of multiphonic sounds
Continuation of a physical model of brass instrument: application to trumpet categorization
International audienceThe system formed by the couple {player-trumpet} falls into the class of non-linear dynamical systems likely to be studied using different numerical tools such as numerical continuation methods. In this study we illustrate the interest of this approach for the categorization of Bb trumpets in the space of some performance descriptors obtained from continuation by the ANM method combined to the Harmonic Balance Method (HBM)
Oscillation threshold of a clarinet model: a numerical continuation approach
This paper focuses on the oscillation threshold of single reed instruments.
Several characteristics such as blowing pressure at threshold, regime
selection, and playing frequency are known to change radically when taking into
account the reed dynamics and the flow induced by the reed motion. Previous
works have shown interesting tendencies, using analytical expressions with
simplified models. In the present study, a more elaborated physical model is
considered. The influence of several parameters, depending on the reed
properties, the design of the instrument or the control operated by the player,
are studied. Previous results on the influence of the reed resonance frequency
are confirmed. New results concerning the simultaneous influence of two model
parameters on oscillation threshold, regime selection and playing frequency are
presented and discussed. The authors use a numerical continuation approach.
Numerical continuation consists in following a given solution of a set of
equations when a parameter varies. Considering the instrument as a dynamical
system, the oscillation threshold problem is formulated as a path following of
Hopf bifurcations, generalizing the usual approach of the characteristic
equation, as used in previous works. The proposed numerical approach proves to
be useful for the study of musical instruments. It is complementary to
analytical analysis and direct time-domain or frequency-domain simulations
since it allows to derive information that is hardly reachable through
simulation, without the approximations needed for analytical approach
Response of an artificially blown clarinet to different blowing pressure profiles
Using an artificial mouth with an accurate pressure control, the onset of the
pressure oscillations inside the mouthpiece of a simplified clarinet is studied
experimentally. Two time profiles are used for the blowing pressure: in a first
set of experiments the pressure is increased at constant rates, then decreased
at the same rate. In a second set of experiments the pressure rises at a
constant rate and is then kept constant for an arbitrary period of time. In
both cases the experiments are repeated for different increase rates. Numerical
simulations using a simplified clarinet model blown with a constantly
increasing mouth pressure are compared to the oscillating pressure obtained
inside the mouthpiece. Both show that the beginning of the oscillations appears
at a higher pressure values than the theoretical static threshold pressure, a
manifestation of bifurcation delay. Experiments performed using an interrupted
increase in mouth pressure show that the beginning of the oscillation occurs
close to the stop in the increase of the pressure. Experimental results also
highlight that the speed of the onset transient of the sound is roughly the
same, independently of the duration of the increase phase of the blowing
pressure.Comment: 14 page
Interaction of reed and acoustic resonator in clarinetlike systems
Sound emergence in clarinetlike instruments is investigated in terms of
instability of the static regime. Various models of reed-bore coupling are
considered, from the pioneering work of Wilson and Beavers ["Operating modes of
the clarinet", J. Acoust. Soc. Am. 56, 653--658 (1974)] to more recent modeling
including viscothermal bore losses and vena contracta at the reed inlet. The
pressure threshold above which these models may oscillate as well as the
frequency of oscillation at threshold are calculated. In addition to Wilson and
Beavers' previous conclusions concerning the role of the reed damping in the
selection of the register the instrument will play on, the influence of the
reed motion induced flow is also emphasized, particularly its effect on playing
frequencies, contributing to reduce discrepancies between Wilson and Beavers'
experimental results and theory, despite discrepancies still remain concerning
the pressure threshold. Finally, analytical approximations of the oscillating
solution based on Fourier series expansion are obtained in the vicinity of the
threshold of oscillation. This allows to emphasize the conditions which
determine the nature of the bifurcation (direct or inverse) through which the
note may emerge, with therefore important consequences on the musical playing
performances
Polynucleobacter necessarius, a model for genome reduction in both free-living and symbiotic bacteria
We present the complete genomic sequence of the essential
symbiont Polynucleobacter necessarius (Betaproteobacteria),
which is a valuable case study for several reasons. First, it is hosted
by a ciliated protist, Euplotes; bacterial symbionts of ciliates are
still poorly known because of a lack of extensive molecular data.
Second, the single species P. necessarius contains both symbiotic
and free-living strains, allowing for a comparison between closely
related organisms with different ecologies. Third, free-living
P. necessarius strains are exceptional by themselves because of
their small genome size, reduced metabolic flexibility, and high
worldwide abundance in freshwater systems. We provide a comparative
analysis of P. necessarius metabolism and explore the
peculiar features of a genome reduction that occurred on an
already streamlined genome. We compare this unusual system
with current hypotheses for genome erosion in symbionts and
free-living bacteria, propose modifications to the presently accepted
model, and discuss the potential consequences of translesion DNA
polymerase loss
Contribution to harmonic balance calculations of self-sustained periodic oscillations with focus on single-reed instruments
International audienceThe harmonic balance method Í‘HBMÍ’ was originally developed for finding periodic solutions of electronical and mechanical systems under a periodic force, but has been adapted to self-sustained musical instruments. Unlike time-domain methods, this frequency-domain method does not capture transients and so is not adapted for sound synthesis. However, its independence of time makes it very useful for studying any periodic solution, whether stable or unstable, without care of particular initial conditions in time. A computer program for solving general problems involving nonlinearly coupled exciter and resonator, HARMBAL, has been developed based on the HBM. The method as well as convergence improvements and continuation facilities are thoroughly presented and discussed in the present paper. Applications of the method are demonstrated, especially on problems with severe difficulties of convergence: the Helmholtz motion Í‘square signalsÍ’ of single-reed instruments when no losses are taken into account, the reed being modeled as a simple spring
A robust and rapid xenograft model to assess efficacy of chemotherapeutic agents for human acute myeloid leukemia
International audienceRelevant preclinical mouse models are crucial to screen new therapeutic agents for acute myeloid leukemia (AML). Current in vivo models based on the use of patient samples are not easy to establish and manipulate in the laboratory. Our objective was to develop robust xenograft models of human AML using well-characterized cell lines as a more accessible and faster alternative to those incorporating the use of patient-derived AML cells. Five widely used AML cell lines representing various AML subtypes were transplanted and expanded into highly immunodeficient non-obese diabetic/LtSz-severe combined immunodeficiency IL2R gamma(null)(c) mice (for example, cell line-derived xenografts). We show here that bone marrow sublethal conditioning with busulfan or irradiation has equal efficiency for the xenotransplantation of AML cell lines. Although higher number of injected AML cells did not change tumor engraftment in bone marrow and spleen, it significantly reduced the overall survival in mice for all tested AML cell lines. On the basis of AML cell characteristics, these models also exhibited a broad range of overall mouse survival, engraftment, tissue infiltration and aggressiveness. Thus, we have established a robust, rapid and straightforward in vivo model based on engraftment behavior of AML cell lines, all vital prerequisites for testing new therapeutic agents in preclinical studies
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