1,020 research outputs found

    La sortida del propi jo per establir una relaciĂł amb els altres

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    Coffee inventory through orbital imagery

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    There are no author-identified significant results in this report

    Deconvolving the information from an imperfect spherical gravitational wave antenna

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    We have studied the effects of imperfections in spherical gravitational wave antenna on our ability to properly interpret the data it will produce. The results of a numerical simulation are reported that quantitatively describe the systematic errors resulting from imperfections in various components of the antenna. In addition, the results of measurements on a room-temperature prototype are presented that verify it is possible to accurately deconvolve the data in practice.Comment: 5 pages, 2 figures, to be published in Europhysics Letter

    Hypoxia Inducible Factor as a Central Regulator of Metabolism – Implications for the Development of Obesity

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    The hypothalamus plays a major role in the regulation of food intake and energy expenditure. In the last decade, it was demonstrated that consumption of high-fat diets triggers the activation of an inflammatory process in the hypothalamus, inducing neurofunctional alterations and contributing to the development of obesity. Hypoxia-inducible factors (HIFs) are key molecules that regulate cellular responses to inflammation and hypoxia, being essential for the normal cell function and survival. Currently, evidence points to a role of HIF pathway in metabolic regulation that could also be involved in the progression of obesity and metabolic diseases. The challenge is to understand how HIF modulation impacts body mass gain and metabolic disorders such as insulin resistance. Distinct animal models with tissue-specific knocking-out or overexpression of hypoxia signaling pathway genes revealed a cell-specificity in the activation of HIF pathways, and some of them have opposite phenotypes among the various HIFs gain- and loss-of-function mouse models. In this review, we discuss the major findings that provide support for a role of HIF pathway involvement in the regulation of metabolism, especially in glucose and energy homeostasis

    HIT: a Human-Inspired Trust model

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    This paper presents a new approach to assign trust levels in ad hoc networks. Our system is inspired by the human concept of trust. The trust level considers the recommendation of trustworthy neighbors and their own experience. For the recommendation computation, we take into account not only the trust level, but also its accuracy and the relationship maturity. We also propose the Recommendation Exchange Protocol (REP), which minimizes the number of exchanged messages. The results show the efficacy of the system and the influence of main parameters.8th IFIP/IEEE International conference on Mobile and Wireless CommunicationRed de Universidades con Carreras en Informática (RedUNCI
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