2,980 research outputs found
Superconducting and structural properties of plasma sprayed YBaCuO layers deposited on metallic substrates
The properties of plasma sprayed Y-Ba-Cu-O coatings deposited on metallic substrates are studied. Stainless steel, nickel steels and pure nickel are used as substrate. Y-Ba-Cu-O deposited on stainless steel and nickel steel reacts with the substrate. This interaction can be suppressed by using an yttria-stabilized zirconia (YsZ) diffusion barrier. However, after heat treatment the Y-Ba-Cu-O layers on YsZ show cracks perpendicular to the surface. As a result the critical current density is very low. The best results are obtained for Y-Ba-Cu-O deposited on pure nickel; here no cracks perpendicular to the surface are observed. The critical current increases with the anneal temperature but annealing for longer than 10 h does not seem to improve the superconducting properties any further
Assessment of Aeroacoustic Simulations of the High-Lift Common Research Model
This paper presents further validation of PowerFLOWR aeroacoustic simulations of the High-Lift Common Research Model through comparisons with experimental data from a recently completed wind tunnel test. Preliminary time- averaged surface pressure and microphone array data from the experiment are in reasonably good agreement with the simulations, and the slat is shown to be a dominant noise source on this model. The simulations did not predict slat tones that were very prominent in the experiment, but they did capture the broadband component of slat noise in the low-frequency range up to 1 kHz at full scale. Future tests are planned to demonstrate slat noise reduction technology, and simulations are being used to guide this development
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Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.
Cancer cell lines are a cornerstone of cancer research but previous studies have shown that not all cell lines are equal in their ability to model primary tumors. Here we present a comprehensive pan-cancer analysis utilizing transcriptomic profiles from The Cancer Genome Atlas and the Cancer Cell Line Encyclopedia to evaluate cell lines as models of primary tumors across 22 tumor types. We perform correlation analysis and gene set enrichment analysis to understand the differences between cell lines and primary tumors. Additionally, we classify cell lines into tumor subtypes in 9 tumor types. We present our pancreatic cancer results as a case study and find that the commonly used cell line MIA PaCa-2 is transcriptionally unrepresentative of primary pancreatic adenocarcinomas. Lastly, we propose a new cell line panel, the TCGA-110-CL, for pan-cancer studies. This study provides a resource to help researchers select more representative cell line models
A nationwide survey of patient problem occurrence across different nursing healthcare sectors
Aim: The aim of this study was to determine the patient problems that nurses encounter in different clinical settings and the extent to which they report being able to influence those patient problems. Design: Exploratory online survey research. Method Data were collected through an online questionnaire. We prepared a 2 × 2 matrix to compare the rate of occurrence against the average level of reported influence. Descriptive statistics were used for the data analysis. Results: A total of 440 nurses working in different settings completed the questionnaire. Nurses report having the most influence on patient problems related to self-care, mobility and functions of the skin. Nurses experience less influence on problems with voice/speech and the tasks required for participation in work/employment
Comparative Study of Active Flow Control Strategies for Lift Enhancement of a Simplified High-Lift Configuration
Numerical simulations have been performed for a simplified high-lift (SHL) version of the Common Research Model (CRM) configuration, where the Fowler flaps of the conventional high-lift (CRM-HL) configuration are replaced by a set of simple hinged flaps. These hinged flaps are equipped with integrated modular active flow control (AFC) cartridges on the suction surface, and the resulting geometry is known as the CRM-SHL-AFC configuration. The main objective is to make use of AFC devices on the CRM-SHL-AFC configuration to recover the aerodynamic performance (lift) of the CRM-HL configuration. In the current paper, a Lattice Boltzmann method-based computational fluid dynamics (CFD) code, known as PowerFLOWQ is used to simulate the entire flow field associated with the CRM-SHL-AFC configuration equipped with several different types of AFC devices. The transonic version of the PowerFLOWQ code that has been validated for high speed flows is used to accurately simulate the flow field generated by the high-momentum actuators required to mitigate reversed flow regions on the suction surfaces of the main wing and the flap. The numerical solutions predict the expected trends in aerodynamic forces as the actuation levels are increased. More efficient AFC systems and actuator arrangements emerged based on the parametric studies performed prior to a Fall 2018 wind tunnel test. Preliminary comparisons of the numerical solutions for lift and surface pressures are presented here with the experimental data, demonstrating the usefulness of CFD for predicting the flow field and lift characteristics of AFC-enabled high-lift configurations
Binary coalescence from case A evolution -- mergers and blue stragglers
We constructed some main-sequence mergers from case A binary evolution and
studied their characteristics via Eggleton's stellar evolution code. Both total
mass and orbital angular momentum are conservative in our binary evolutions.
Some mergers might be on the left of the ZAMS as defined by normal surface
composition on a CMD because of enhanced surface helium content. The study also
shows that central hydrogen content of the mergers is independent of mass. As a
consequence, we fit the formula of magnitude and B-V of the mergers when they
return back to thermal equilibrium with maximum error 0.29 and 0.037,
respectively. Employing the consequences above, we performed Monte Carlo
simulations to examine our models in NGC 2682 and NGC 2660. In NGC 2682, binary
mergers from our models cover the region with high luminosity, but its
importance is much less than that of AML. Our results are well-matched to the
observations of NGC2660 if there is about 0.5Mo of mass loss in the merger
process.Comment: 14 pages, 12 figures. accepted by MNRA
Block-structured grids for complex aerodynamic configurations: Current status
The status of CFD methods based on the use of block-structured grids for analyzing viscous flows over complex configurations is examined. The objective of the present study is to make a realistic assessment of the usability of such grids for routine computations typically encountered in the aerospace industry. It is recognized at the very outset that the total turnaround time, from the moment the configuration is identified until the computational results have been obtained and postprocessed, is more important than just the computational time. Pertinent examples will be cited to demonstrate the feasibility of solving flow over practical configurations of current interest on block-structured grids
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