Külhoni szavazás : kontextusok és Kárpát-medencei percepciók

A tanulmány áttekinti a többes állampolgársághoz kapcsolódó politológiai, jogi vonatkozások néhány sajátosságát, és néhány ország vonatkozásában röviden kitér ezek hatásaira. Írásunk második részében egy Kárpát-medencei fókuszcsoportos vizsgálat keretében azt vizsgáltuk, a könnyített honosítás által a külhoni magyarok hogyan vélekednek a magyarországi szavazásokon való részvételről

Applicability of ultra performance convergence chromatography, a new generation of supercritical fluid chromatography, for the analysis of pesticide residues

Monitoring and controlling wide variety of pesticide residues is a crucial challenge of food safety. In our study ultra-performance convergent chromatography (UPC2), as the new generation of supercritical fluid chromatography coupled with ESI-MS/MS system was applied to separate a set of pesticides to investigate their chromatographic behavior under various UPC2 conditions. 30 components were selected representing the GC and LC measurable components. Capacity factors obtained from LC and GC runs UPC2-PDA were compared. Based on our data UPC2 should be considered as an alternative chromatographic approach with separation mechanisms not yet fully characterized. Interestingly the type of mobile phase modifier influences the ionization in an ESI-MS system

PROCESSING OF SLAR IMAGES

An X-band Side Looking Airborne Radar (SLAR) has been developed and constructed. The recorded raw images had to be corrected both radiometrically and geometrically. To achieve this goal, different digital image processing methods have been applied. The obtained results are images fitting well to the original maps of the landscapes. Final resolution of the corrected images is 10 ... 15 m

IMPROVING QUALITY OF LIFE AFTER HIP REVISION ARTHROPLASTY

Nowadays the number of primary arthroplasties is growing and revision arthroplasty is becoming increasingly necessary. In this study we intend to examine the effectiveness of arthroplasties and assess the quality of life. We included 35 patients with revision arthroplasty and 35 primary hip arthroplasty patients who had surgery between 2011 and 2012 in the study. To examine the results we used the modified Harris hip score and the Rosser matrix, which was completed before surgery and 2-3 years after the procedure. We observed a statistically significant improvement: from 34 preoperative Harris hip score 75 at the 2 years postsurgery assessment and 72 at the 3 years postoperative assessment (p <0.0001). Significant improvements were also registered when assessing the health state with the Rosser matrix. The effect for the Harris score had a value of 2.06 which testifies the revision surgery has a high effectiveness. This means that with this kind of procedures dramatic improvement in quality of life can be achieved

CERAMIC-ON-CERAMIC TOTAL HIP ARTHROPLASTY IN YOUNG PATIENTS WITH FEMORAL-HEAD OSTEONECROSIS - SHORTTERM RESULTS

Aim: the increasing number of total hip arthroplasties in case of young, physically active patients means an increasing number of revision surgeries as well. For these patients the use of ceramic bearings could be an appropriate solution because of its reduced wear and a predicted longer lifetime. In this paper we would like to present our short experiences with non-cemented, ceramic-on-ceramic total hip prosthesis, in case of young patients. Materials and Methods: between January 2011 and December 2012, 32 hip arthroplasties were performed in case of 31 young patients diagnosed with avascular necrosis of the femoral head. The clinical and radiological follow-up of these patients was carried out for an average of 1,5 year. The average age was 47 years (25-51) in the moment of the surgery. The clinical assessment of the patients were carried out by the Harris Hip Score and Visual Analog Scale, performed before and 3, 6, 12 month after surgery. The radiological evaluation was based on the anteroposterior and axial radiographs performed at the above mentioned time points. Results: in each cases the bony ingrowth of the prosthesis took place. No stressshielding phenomenon was observed at the proximal part of the femur. In one case at six month control X-ray we noticed the damage of the ceramic insert and no further complications were observed. The patient refused the revision surgery for now. Conclusions: the fourth-generation ceramic component for non-cemented endoprosthesis used in case of young patients has very good early clinical and radiological results

ILIOPSOAS IMPINGEMENT AFTER TOTAL HIP ARTHROPLASTY - FINITE ELEMENT ANALYSIS

Aim of this paper. Is to study the iliopsoas impingement with threedimensional modeling (3D) after total hip arthroplasty in extended position of the hip in case of 28 and 36 mm diameter prosthetic heads and the acetabular component in malposition (retroversion). Material and methods. We performed a 3D reconstruction of the pelvic bone, the left femur and left iliopsoas muscle of a 27 year old male based on CT images. After that we created a solid body that we used for the arthroplasty performed in the variants mentioned above and we used the finite element method for the analyses. Results. There were no traces of impingement with the 28 mm and 36 mm diameter femoral head, when the joint is in extension. When the acetabular component was in malposition, we found a stress aerie on the iliopsoas muscle and acetabular component meeting point. Conclusion. In our research, we demonstrated by 3D modeling and finite element analysis that after total hip arthroplasty using a large diameter femoral head, with the hip in extension, there is no pressure on the surface of iliopsoas muscle, contrary with the case of the acetabular component in retroversion. We can avoid this placing the acetabular component in angle of 45o inclination and 10o anteversion

ILIOPSOAS IMPINGEMENT AFTER TOTAL HIP ARTHROPLASTY - FINITE ELEMENT ANALYSIS

Aim of this paper. Is to study the iliopsoas impingement with threedimensional modeling (3D) after total hip arthroplasty in extended position of the hip in case of 28 and 36 mm diameter prosthetic heads and the acetabular component in malposition (retroversion). Material and methods. We performed a 3D reconstruction of the pelvic bone, the left femur and left iliopsoas muscle of a 27 year old male based on CT images. After that we created a solid body that we used for the arthroplasty performed in the variants mentioned above and we used the finite element method for the analyses. Results. There were no traces of impingement with the 28 mm and 36 mm diameter femoral head, when the joint is in extension. When the acetabular component was in malposition, we found a stress aerie on the iliopsoas muscle and acetabular component meeting point. Conclusion. In our research, we demonstrated by 3D modeling and finite element analysis that after total hip arthroplasty using a large diameter femoral head, with the hip in extension, there is no pressure on the surface of iliopsoas muscle, contrary with the case of the acetabular component in retroversion. We can avoid this placing the acetabular component in angle of 45o inclination and 10o anteversion

A stresszfehérjék és lipidek membrán kapcsolt homeosztázisa = Coupled homeostasis of membrane lipids and stress proteins

1. Megállapítottuk, hogy az IbpA/B fehérje in vivo különböző mértékben asszociálódik az E. coli membrán(ok)hoz. Langmuir-Blodget monolayer kísérletekben igazoltuk az IbpAB membránlipid kötését. Jellemeztük az E. coli IbpAB- mutánst mind molekuláris, mind fiziológiás szinten. Megállapítottuk, hogy az IbpAB- mutáns törzsek rendelkeznek „membrán-fenotípussal”, a vad típustól markánsan eltérő lipid zsírsavösszetétellel, valamint megváltozott fluiditással és permeabilitással. A lipidomikai kísérletek rávilágítottak a fluiditásváltozás kompenzációs jellegére, a homeosztatikus membrán adaptáció elvének megfelelően. A membránlipidek és hősokkfehérjék kapcsolatának egy másik dimenziójára kívántunk rávilágítani a vad típusú és mutáns törzsek globális „transcriptome” analízisével. A wt és az IbpAB mutánsok mRNS profilja hatalmas eltérést mutat, a változások gének egész sorát érintik, amelyek megértése további kísérleteket kíván. 2. Munkánk során elsőként igazoltuk Synechocystisben a DnaK2 fehérje szubfrakciójának tilakoid asszociációját. A DnaK2 részleges hiánya megváltoztatta a tilakoid membrán lipid- és zsírsavösszetételét, valamint a membrán fizikai állapotát. A membránváltozások befolyásolják a tilakoid membrán működését, ami eltérő hő- illetve UV-B stresszérzékenységben is megnyilvánul. A DnaK2 protein részleges hiánya UV károsodás után a PSII “repair” részleges inhibícióját eredményezte. Ily módon kimutattuk egy új, membránasszociált DnaK-függő stresszvédő mechanizmus létezését. | 1. In E. Coli the small heat shock protein IbpAB interacts with membranes in vivo and in vitro and rigidifides it which counterbalances heat-induced fluidization, indicating a protective role of this Hsp in the heat-shocked membrane. IbpAB- cells have an increased membrane permeability but higher outer membrane transition temperature and better survival at heat challenge. The improved survival is linked to the altered membrane phenotype. These include unique fatty acid changes and fluidization in the hydrophobic core of the membranes, which are associated with better survival upon heat challenge. 2. We have shown that in Synechocystis PCC6803 DnaK2 chaperon interacts with the thylakoid membrane, especially with the phosphatidyl glycerol (PG) lipid of the thylakoid. In DnaK2- cells the fatty acid composition of the thylakoid membrane differed from that of the wild type resulting in altered physico-chemical properties. We exposed cells to UV-B damage and concluded, that lack of the DnaK2 leads to partial inhibition of PSII repair and the rate of forward electron transport between QA and QB quinone electron acceptors is slowed down. PG plays an important role in binding extrinsic proteins required for a functional Mn cluster on the donor side of PSII. The binding of DnaK2 may take place trough binding specifically to PG and/or with the PSII complex. This interaction leads directly or indirectly to change in membrane fluidity which influences PSII electron transport