Pilot interaction with automated airborne decision making systems

The current research is focused on detection of human error and protection from its consequences. A program for monitoring pilot error by comparing pilot actions to a script was described. It dealt primarily with routine errors (slips) that occurred during checklist activity. The model to which operator actions were compared was a script. Current research is an extension along these two dimensions. The ORS fault detection aid uses a sophisticated device model rather than a script. The newer initiative, the model-based and constraint-based warning system, uses an even more sophisticated device model and is to prevent all types of error, not just slips or bad decision

Divine Light Academy-Library Information System (DLA-LIS)

In recent times with the advent of technology, information has become a crucial aspect of any business. Strength or downfall of any business depends solely on the company\u27s acquisition of information. With this trend in mind, it is of no wonder that a lot of companies are starting to invest in computerized systems. DLA Library Information System, is one such system, which will not only increase the speed of acquisition of information but also reduce the amount effort put into the workload. The primary mission of the library is to provide access to information. In so doing, it will organize, and make readily available any collection of recorded knowledge that will support the instructional, research, and service goals of the school\u27s constituencies, namely, the faculty, the student, and the staff. The proposed system comprises of five major activities of the library: acquisition of new materials, cataloguing, circulation, inventory and the On-line Public Accessing Catalogue which serves as a tool for their daily operations and an added method of search for the library users

Liposome immune lysis assay (LILA) for gelonin

A complement-mediated liposome immune lysis assay using entrapped calcein was developed for a plant toxin gelonin. Gelonin was covalently coupled to DPPE, and then adsorbed on to the surface of liposomes. Such antigen-bearing liposomes when incubated with anti-gelonin antibody in the presence of guinea pig complement undergo lysis. The detection range is from 3 ng to 60 ng. The method was used to monitor isolation of gelonin by affinity chromatography. It was observed that a minor peak in addition to the major one comes with gelonin, shared common epitopes/epitope with gelonin immunological reaction. This was further confirmed by SDS-gel electrophoresis indicating the former being an isoform of gelonin. A comparative study of the immunocross-reactivity of ricin and A chain with anti-gelonin antibody was carried out. It was found that while ricin A chain cross-reacted extensively with gelonin antibody and intact ricin elicited little or no cross-reactivity. It is suggested that the present LILA may be employed for the detection and quantitation of ricin A chain by this LILA method

LONG-TERM ASSESSMENT OF EFFICACY AND SAFETY OF L1, AN ORAL IRON CHELATOR, IN TRANSFUSION DEPENDENT THALASSEMIA - INDIAN TRIAL

From August 1989 to May 1991, 52 patients with transfusion dependent thalassaemia major received L1 (1,2-dimethyl-3-hydroxypyrid-4-one), the oral iron chelator, for a period of 3-21 months (mean+/-SD: 14.2+/-6.8). Mean (+/-SD) urinary iron excretion varied from 6.2+/-4.6 mg/d on 25 mg/kg/d of L1 to 42.3+/-37.1 mg/d on 100 mg/kg/d of L1. Mean (+/-SD) drop in S ferritin was 1465+/-990 mug/l after 5.0+/-0.8 months to 3641.2+/-2299.3 mug/l after 20.1+/-0.9 months of therapy. There was no evidence of neutropenia, thrombocytopenia, ear or eye toxicity. L1-related arthralgia, which was reversible on dose reduction or stoppage, was seen in 20 patients (38.5%), while minor gastrointestinal (GI) tract symptoms occurred in seven (3.5%) cases. We conclude that although L1 is an effective iron chelator, further studies are required to understand the mechanism of L1 related arthralgia and also to find a safer but effective dose on which incidence of L1 related arthralgia is minimal