Identificación de las emociones en las diferentes etapas de cáncer infantil

El presente trabajo de grado tiene como propósito identificar las emociones en pacientes que estén comenzando y hayan terminado el tratamiento de cáncer infantil. Este estudio presenta un enfoque cualitativo, en el cual la recolección de información se realizó mediante dos instrumentos, entrevistas semiestructuradas aplicadas a pacientes y cuidadores y talleres de suscitación de emociones realizados con los niños diagnosticados. La selección de los cuatro participantes se realizó a conveniencia debido a que había mayor disponibilidad y acceso a la población en la Fundación Segundos de Vida, la cual alberga niños y adolescentes con cáncer en la ciudad de Bogotá. El análisis de la información se estructuro en dos niveles: intrasujetos e intersujetos, para así lograr observar diferencias y/o convergencias entre los sujetos en las diferentes etapas del cáncer infantil.The purpose of this paper is to identify emotions in patients who are beginning or have finished the treatment of childhood cancer. This study presents a qualitative approach, in which the collection of information was carried out using as a method the semi-structured interview, contextual analysis and workshops adapted for the population. The selection of participants was carried out at convenience because there was a greater availability and access to the population at the Segundos de Vida Foundation, which houses children and adolescents with cancer in the city of Bogotá. An analysis of the interviews was conducted, which focused on comparing the intersubject and intrasubject results in order to observe differences and / or convergences between the subjects in the different stages of childhood cancer.Psicólogo (a)Pregrad

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field