A Privacy Protection Mechanism for Mobile Online Social Networks

A Location sharing system is the most critical component in mobile online social networks (MOSNS).Huge number of user\u27s location information will be stored by the service providers. In addition to the location privacy and social network privacy cannot be guaranteed to the user in the earlier work. Regarding the enhanced privacy against the inside attacker implemented by the service provider in (MOSNS), we initiate a new architecture with multiple servers .It introduces a protected solution which supports a location sharing among friends and strangers. The user friend set in each query is submitted to the location server it divides into multiple subset by the location server. If the user makes a query to the server the data can be retrieved only for the registered users instead of all. We use Three Layer of Security likely, High, Medium and Low for the Privacy implementation. Simultaneously with a location sharing it offers check ability of the searching results reoccurred from the servers. We also prove that the new construction is safe under the stronger security model with enhanced privacy

The MILLET MISSION: The potential to combat non-communicable diseases and future research opportunities in India

NCD Burden and the role of nutritionChronic diseases, often known as non-communicable diseases (NCDs), pose a significant threat to worldwide public health. As per World Health Organisation (WHO), NCDs account for 74% of all fatalities worldwide, with cardiovascular disease, cancer, respiratory disease, and diabetes being the leading causes.[1] Inadequate nutrition, including diets heavy in sugar, salt, saturated and trans fats, and deficient in fruits, vegetables, whole grains, and lean protein sources, is a significant risk factor for NCDs. The World Health Organization suggests a diet rich in fruits, vegetables, whole grains, nuts, and seeds and low in processed foods, sugar, saturated and trans fats.[2

Health-Beneficial Phenolic Aldehyde in Antigonon leptopus Tea

Tea prepared from the aerial parts of Antigonon leptopus is used as a remedy for cold and pain relief in many countries. In this study, A. leptopus tea, prepared from the dried aerial parts, was evaluated for lipid peroxidation (LPO) and cyclooxygenase (COX-1 and COX-2) enzyme inhibitory activities. The tea as a dried extract inhibited LPO, COX-1 and COX-2 enzymes by 78%, 38% and 89%, respectively, at 100 μg/mL. Bioassay-guided fractionation of the extract yielded a selective COX-2 enzyme inhibitory phenolic aldehyde, 2,3,4-trihydroxy benzaldehyde. Also, it showed LPO inhibitory activity by 68.3% at 6.25 μg/mL. Therefore, we have studied other hydroxy benzaldehydes and their methoxy analogs for LPO, COX-1 and COX-2 enzymes inhibitory activities and found that compound 1 gave the highest COX-2 enzyme inhibitory activity as indicated by a 50% inhibitory concentration (IC50) at 9.7 μg/mL. The analogs showed only marginal LPO activity at 6.25 μg/mL. The hydroxy analogs 6, 7 and 9 showed 55%, 61% and 43% of COX-2 inhibition at 100 μg/mL. However, hydroxy benzaldehydes 3 and 12 showed selective COX-1 inhibition while compounds 4 and 10 gave little or no COX-2 enzyme inhibition at 100 μg/mL. At the same concentration, compounds 14, 21 and 22 inhibited COX-1 by 83, 85 and 70%, respectively. Similarly, compounds 18, 19 and 23 inhibited COX-2 by 68%, 72% and 70%, at 100 μg/mL. This is the first report on the isolation of compound 1 from A. leptopus tea with selective COX-2 enzyme and LPO inhibitory activities

Study of simple sequence repeat (SSR) polymorphism for biotic stress resistance in elite rice variety JGL 1798

To provide ready to use markers for back ground selection in marker assisted breeding of rice, we used GPP 2 as donor parent for xa13, Xa21, Gm4 resistance to bacterial blight, gall midge and NLR 145 as another donor parent for Pi-kh gene resistance to blast and JGL 1798 as recurrent parent was investigated using 128 simple sequence repeat (SSR) primers covered on chromosome number 1-12. The results reveal that 36 HRM primers showed distinct polymorphism among the donor and recurrent parents studied indicating the robust nature of microsatellites in revealing polymorphism. Based on this study, the large range of similarity values for related cultivars using microsatellites provides greater confidence for the assessment of simple sequence repeats (SSR) polymorphism.Keywords: Simple sequence repeats (SSR), parental polymorphism, JGL 1798, hyper variable markersAfrican Journal of Biotechnology Vol. 12(40), pp. 5833-583

Effectiveness of Yoga Therapy on the Well Being of Hypertensive Women residing at Dooming Kuppam in Chennai

INTRODUCTION: Hypertension is a major Chronic life style disease and an important public health problem. Recent report indicates that approximately 1 billion people world wide have high blood pressure and this number is expected to increase to 1.56 billion people by the year 2025. Well being is a concept that combines individual’s health, quality of life and their satisfaction. The well ness education teaches health way and include topics as physical awareness yoga therapy is a low cost, non pharmacological yoga therapy is very simple of the physical exercise. It is emphasized in the home setup with the daily activities to decrease the blood pressure and to avoid blood pressure related complication. AIM OF THE STUDY: 1. To assess the pretest and post test level of well being among the experimental and control group of women. 2. To determine the effectiveness of yoga therapy on level of well being among experimental group. 3. To associate between the well being of the hypertensive women. METHODOLOGY: A quasi experimental study was conducted to determine the effectiveness of yoga therapy on the well being of hypertensive women residing of dooming kuppam in Chennai – 4. Sample were selected by non probability convenient sampling as per the inclusive criteria. The data was collected using a structured questionnaire by the investigator and analysed using mean, standard deviation, Independent t test and chi-square. RESULT: In the (T=60) experimental group (N= 30), the pretest mean score of well being was 57.67 with standard deviation 4.38 and the post test mean score of well being was 78.40 with standard deviation. 10.48. The calculated "t" value of 10.701 was statistically highly significant at P<0.001 level. The control group (N=30) pretest mean score of well being was 59.63 with standard deviation. 5.68 and the post test mean score of well being was 60.27 with standard deviation 6.35 the ‘t’ value of 0.720 had not shown non statistical significance. CONCLUSION: Thus the study concludes that there is significant in the level of well being in the experimental group than the control group

Health-Beneficial Phenolic Aldehyde in Antigonon leptopus Tea.

Tea prepared from the aerial parts of Antigonon leptopus is used as a remedy for cold and pain relief in many countries. In this study, A. leptopus tea, prepared from the dried aerial parts, was evaluated for lipid peroxidation (LPO) and cyclooxygenase (COX-1 and COX-2) enzyme inhibitory activities. The tea as a dried extract inhibited LPO, COX-1 and COX-2 enzymes by 78%, 38% and 89%, respectively, at 100 μg/mL. Bioassay-guided fractionation of the extract yielded a selective COX-2 enzyme inhibitory phenolic aldehyde, 2,3,4-trihydroxy benzaldehyde. Also, it showed LPO inhibitory activity by 68.3% at 6.25 μg/mL. Therefore, we have studied other hydroxy benzaldehydes and their methoxy analogs for LPO, COX-1 and COX-2 enzymes inhibitory activities and found that compound 1 gave the highest COX-2 enzyme inhibitory activity as indicated by a 50% inhibitory concentration (IC(50)) at 9.7 μg/mL. The analogs showed only marginal LPO activity at 6.25 μg/mL. The hydroxy analogs 6, 7 and 9 showed 55%, 61% and 43% of COX-2 inhibition at 100 μg/mL. However, hydroxy benzaldehydes 3 and 12 showed selective COX-1 inhibition while compounds 4 and 10 gave little or no COX-2 enzyme inhibition at 100 μg/mL. At the same concentration, compounds 14, 21 and 22 inhibited COX-1 by 83, 85 and 70%, respectively. Similarly, compounds 18, 19 and 23 inhibited COX-2 by 68%, 72% and 70%, at 100 μg/mL. This is the first report on the isolation of compound 1 from A. leptopus tea with selective COX-2 enzyme and LPO inhibitory activities

Stemodin-derived analogues with lipid peroxidation, cyclooxygenase enzymes and human tumour cell proliferation inhibitory activities

A series of analogues, derived from the antiviral and cytotoxic diterpene stemodin, were prepared and evaluated for their lipid peroxidation (LPO), cyclooxygenase enzyme-1 (COX-1) and -2 (COX-2), and tumour cell proliferation inhibitory activities. Oxidation of stemodin produced stemodinone, which was then converted to stemod-12-en-2-one. Reaction of the latter under Petrow conditions (bromine; silver acetate/pyridine) yielded mainly dibrominated abeo-stachanes. Solvolysis of the dibromo compounds gave products of hydrolysis, some with rearranged skeleta. In the lipid peroxidation inhibitory assay three of the compounds exhibited prominent activity. Interestingly, all the analogues showed higher COX-1 enzyme inhibition than COX-2. Although a few of the diterpenes limited the growth of some human tumour cell lines, most compounds induced proliferation of such cells