27 research outputs found

    Sacroiliitis secondary to catheter-related bacteremia due to Mycobacterium abscessus (sensu stricto).

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    International audienceWe describe a case of sacroiliitis secondary to catheter-related bacteremia due to Mycobacterium abscessus (sensu stricto). This case confirms that MultiLocus sequence typing and variable-number tandem-repeat methods are very robust techniques to identify the pathogen species and to validate molecular epidemiological links among complex M. abscessus isolates

    Heat accumulation during infrared stimulation impacts the response of ex vivo rat sciatic nerve

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    Infrared neural stimulation (INS) is a neuromodulation technique that involves short optical pulses delivered to the neural tissue, resulting in the initiation of action potentials. In this work, we studied the compound neural action potentials (CNAP) generated by INS in five ex vivo sciatic nerves. A 1470 nm laser emitting a sequence of 0.4 ms light pulses with a peak power of 10 W was used. A single 4 mJ stimulus is not capable of eliciting a nerve response. However, repetition of the optical stimuli resulted in the induction of CNAPs. Heat accumulation induced by repetition rates as high as 10 Hz may be involved in the increase in CNAP amplitude. This sensitization effect may help to reduce the pulse energy required to evoke CNAP. In addition, these results highlight the importance of investigating the role of the slow nerve temperature dynamics in INS.info:eu-repo/semantics/inPres

    A Setup for Conduction Velocities and Temperature Gradients Measurements during Infrared Neurostimulation

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    Infrared Neural Stimulation (INS) is a novel neuromodulation technique involving a rapid temperature increase of the neuron membrane, resulting in action potential triggering. This paper describes an experimental setup developed to measure the spatiotemporal temperature gradients at the surface of an ex vivo sciatic nerve. The setup is also designed to measure the conduction velocity of the nervous fibers excited by INS, with the aim of determining the type of fibers activated during optical stimulation. Two animal experiments successfully validated the setup and provided encouraging results on (1) the impact of heat accumulation on INS and (2) the difference in nerve fibers excited by optical and electrical nerve stimulation
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