53 research outputs found

    Investigating the Impact of Online Service Convenience on Customer Engagement, Attitude and Intention to Use Food Delivery Apps

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    Furthermore, the role of customer engagement has been examined in relation to attitudes and intentions to use mobile food delivery apps. The data was collected in five malls of the National Capital Region (NCR) of India through a structured questionnaire. The convenience sampling method was employed, resulting in 161 responses. The Adanco 2.2 software was used to analyze the responses. Since this study represents the first attempt in the context of food delivery apps, its findings have implications for both academics and marketers

    Pain track analysis during gestation using machine learning techniques

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    During the gestation period women experience Braxton Hicks which is called the false labor, contractions during the second trimester. These contractions are not in regular intervals and also they are often unnoticed. The real labour or the true labour contractions develop late in the third trimester of the gestation usually beyond 36th week (excluding pre-term birth). Some women often fail to identify these pains in the third trimester of the gestation where an efficient facial recognition algorithm along with the support vector machine (SVM) helps them to identify these pains and take optimum care of themselves. The authors in this paper convey a mechanism to identify the pains effectively by creating a database of images pertaining to the pregnant women, her emotional states through out the pregnancy. Using MATLAB the algorithm of decision tree is implemented and the values obtained from them help us analyze the pain type efficiently

    Isolation, characterization and antifungal docking studies of wortmannin isolated from Penicillium radicum

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    During the search for a potent antifungal drug, a cell-permeable metabolite was isolated from a soil isolate taxonomically identified as Penicillium radicum. The strain was found to be a potent antifungal agent. Production conditions of the active compound were optimized and the active compound was isolated, purified, characterized and identified as a phosphoinositide 3-kinase (PI3K) inhibitor, commonly known as wortmannin (Wtmn). This is very first time we are reporting the production of Wtmn from P. radicum. In addition to its previously discovered anticancer properties, the broad spectrum antifungal property of Wtmn was re-confirmed using various fungal strains. Virtual screening was performed through molecular docking studies against potential antifungal targets, and it was found that Wtmn was predicted to impede the actions of these targets more efficiently than known antifungal compounds such as voriconazole and nikkomycin i.e. 1) mevalonate-5-diphosphate decarboxylase (1FI4), responsible for sterol/isoprenoid biosynthesis; 2) exocyst complex component SEC3 (3A58) where Rho-and phosphoinositide-dependent localization is present and 3) Kre2p/Mnt1p a Golgi alpha1,2-mannosyltransferase (1S4N) involved in the biosynthesis of yeast cell wall glycoproteins). We conclude that Wtmn produced from P. radicum is a promising lead compound which could be potentially used as an efficient antifungal drug in the near future after appropriate structural modifications to reduce toxicity and improve stability.Peer reviewe

    Towards real-time topical detection and characterization of FDG dose infiltration prior to PET imaging

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    To dynamically detect and characterize 18F-fluorodeoxyglucose (FDG) dose infiltrations and evaluate their effects on positron emission tomography (PET) standardized uptake values (SUV) at the injection site and in control tissue

    Report from a symposium on catalyzing primary and secondary prevention of cancer in India

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    PurposeOral, breast, and cervical cancers are amenable to early detection and account for a third of India’s cancer burden. We convened a symposium of diverse stakeholders to identify gaps in evidence, policy, and advocacy for the primary and secondary prevention of these cancers and recommendations to accelerate these efforts. MethodsIndian and global experts from government, academia, private sector (health care, media), donor organizations, and civil society (including cancer survivors and patient advocates) presented and discussed challenges and solutions related to strategic communication and implementation of prevention, early detection, and treatment linkages.ResultsInnovative approaches to implementing and scaling up primary and secondary prevention were discussed using examples from India and elsewhere in the world. Participants also reflected on existing global guidelines and national cancer prevention policies and experiences.ConclusionsSymposium participants proposed implementation-focused research, advocacy, and policy/program priorities to strengthen primary and secondary prevention efforts in India to address the burden of oral, breast, and cervical cancers and improve survival

    X-ray photoelectron spectroscopic study of silicon surface passivation in alcoholic iodine and bromine solutions

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    We report an X-ray photoelectron spectroscopic (XPS) study of silicon surfaces passivation using alcoholic solutions of iodine and bromine where different behavior with two systems is observed. The minority carrier lifetime determined by microwave photoconductive decay method showed better surface passivation for iodine-alcoholic system with HF preconditioning step. The iodine-ethanol (I-E) passivated samples show strong Si-I bonding (two times) in Si core level spectra for the samples without oxide (25.5%) compared with oxide (10.2%) counterpart. However, bromine-ethanol (B-E) passivated samples show higher Si-Br bonding strength in the samples with oxide (24.7%) compared to without oxide specimens (12.0%). This may be the reason of difference in passivation behavior of I-E and B-E systems. Higher O-Br bonding in O core level spectra of B-E passivated samples with oxide (35.8%), compared to without oxide (20.7%), results in comparable lifetime values in both with and without preconditioning. To understand the effect of solvent on the passivation, experiments are performed using iodine-methanol (I-M) and bromine-methanol (B-M) solutions and XPS analysis shows similar Si-I, Si-Br, and O-Br bonding trends
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