The Impact of IPv6 on Penetration Testing

In this paper we discuss the impact the use of IPv6 has on remote penetration testing of servers and web applications. Several modifications to the penetration testing process are proposed to accommodate IPv6. Among these modifications are ways of performing fragmentation attacks, host discovery and brute-force protection. We also propose new checks for IPv6-specific vulnerabilities, such as bypassing firewalls using extension headers and reaching internal hosts through available transition mechanisms. The changes to the penetration testing process proposed in this paper can be used by security companies to make their penetration testing process applicable to IPv6 targets

The host genotype affects the bacterial community in the human gastrointestinal tract

The gastrointestinal (GI) tract is one of the most complex ecosystems consisting of microbial and host cells. It is suggested that the host genotype, the physiology of the host and environmental factors affect the composition and function of the bacterial community in the intestine. However, the relative impact of these factors is unknown. In this study, we used a culture-independent approach to analyze the bacterial composition in the GI tract. Denaturing gradient gel electrophoresis (DGGE) profiles of fecal bacterial 16S rDNA amplicons from adult humans with varying degrees of genetic relatedness were compared by determining the similarity indices of the profiles compared. The similarity between fecal DGGE profiles of monozygotic twins were significantly higher than those for unrelated individuals (ts = 2.73, p1-tail = 0.0063, df=21). In addition, a positive relationship (F1, 30 = 8.63, p = 0.0063) between the similarity indices and the genetic relatedness of the hosts was observed. In contrast, fecal DGGE profiles of marital partners, which are living in the same environment and which have comparable feeding habits, showed low similarity which was not significantly different from that of unrelated individuals (ts = 1.03, p1-tail = 0.1561, df=27). Our data indicate that factors related to the host genotype have an important effect on determining the bacterial composition in the GI tract

Top-Down Composition of Software Architectures

This paper discusses an approach for top-down composition of software architectures. First, an architecture is derived that addresses functional requirements only. This architecture contains a number of variability points which are next filled in to address quality concerns. The quality requirements and associated architectural solution fragments are captured in a so-called Feature-Solution (FS) graph. The solution fragments captured in this graph are used to iteratively compose an architecture. Our versatile composition technique allows for pre- and post-refinements, and refinements that involve multiple variability points. In addition, the usage of the FS graph supports Aspect-Oriented Programming (AOP) at the architecture level

Conceptual model of sport-specific classification for para-athletes with intellectual impairment

The present paper describes the conceptual basis of evidence-based classification of para-athletes with intellectual impairment (II). An extensive description of the theoretical and conceptual foundation of the system as currently conceived is provided, as are examples of its applications in the three sports included in the Paralympic programme for II-athletes in 2020 (i.e., athletics, swimming and table tennis). Evidence based classification for II-athletes is driven by two central questions: i. How can intellectual impairment be substantiated in a valid and reliable way, and ii. Does intellectual impairment limit optimal sport proficiency? Evolution of the system and current best practice for addressing these questions are described, and suggestions for future research and development are provided. Challenges of understanding and assessing a complex (multifaceted and intersectional) impairment in the context of sport also are considered

Risicoverevening tussen zorgverzekeraars: Kwantificering modelverbeteringen 1993-2011

Het ex-ante vereveningsmodel van de Zorgverzekeringswet dient verzekeraars te compenseren voor voorspelbare, gezondheidsgerelateerde kostenverschillen tussen verzekerden. Zonder goed vereveningsmodel worden verzekeraars – vanwege het verbod op premiedifferentiatie – geconfronteerd met voorspelbare winsten op gezonde verzekerden en voorspelbare verliezen op chronisch zieken. Voorspelbare winsten en verli