602 research outputs found

    “God and the gods”: Faith and human-made idols in the theology of Karl Barth

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    The First Commandment played an important role in the theology of Karl Barth. His personal obedience to this commandment contributed to his realization that one cannot be comfortable with the Liberal theology of the early twentieth century and accept the theological thinking that supported National Socialism. The First Commandment opened his eyes to see the idols, worldviews, ideologies and evil of his lifetime. The First Commandment is always in the background of his theology that concentrates on God’s revelation in Jesus Christ. Only two of his lectures specifically concentrated on the First Commandment, only one of which was published. Barth, understood the First Commandment as an axiom of theology. It is self-evident; a cornerstone and critical guideline for any theology that is built upon the biblical message. The article argues that if this aspect of Barth’s theology received attention in the Nederduitsch Hervormde Church, we would most probably have been saved from the conflicts concerning the ideology of apartheid and the “people’s church”

    Nog steeds geslote eredienste? Deel 1

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    This paper - in two parts - deals with the question of whether the NederduitschHervormde Church should continue being a church for white persons only. The author argues that this practice is not according to biblical teachings, and at the same time, that it will be unwise to continue it under the future sociopolitical circumstances in South Africa. He therefore calls on the Nederduitsch Hervormde Church to abandon this practice as it will bring the church into conflict with its own theologicaltradition

    Computerised Analysis, Interpretation, Storage and Retrieval of Electrocardiograms

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    A study was undertaken to determine the feasibility of introducing a computerised electrocardiographic analysis and interpretive system as a service to a teaching and referral hospital. Available computer equipment and programmes are considered. The accuracy and quality of the analysis and interpretation of the electrocardiographic contours are basically dependent on such factors as pattern recognition, the criteria adopted for determining abnormalities, the relative values placed on scalar and orthogonal leads and the role of review by the physician. It is concluded that such systems are at a stage where they can feasibly be introduced and should be of advantage in freeing the physician from ,routine measuring and screening of electrocardiograms, thus saving many hours of professional and academic time. Furthermore, such systems can contribute greatly as an educational tool and increase the general knowledge of electrocardiography. Systems for storage and retrieval are also being developed and becoming available. The whole field is a developing one and continuous updating of programmes by the addition of more data, particularly for children, and the introduction of electrocardiographic comparison programmes need to be expedited.S. Afr. Med. J., 48, 1141 (1974)

    Transition to subcritical turbulence in a tokamak plasma

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    Tokamak turbulence, driven by the ion-temperature gradient and occurring in the presence of flow shear, is investigated by means of local, ion-scale, electrostatic gyrokinetic simulations (with both kinetic ions and electrons) of the conditions in the outer core of the Mega-Ampere Spherical Tokamak (MAST). A parameter scan in the local values of the ion-temperature gradient and flow shear is performed. It is demonstrated that the experimentally observed state is near the stability threshold and that this stability threshold is nonlinear: sheared turbulence is subcritical, i.e. the system is formally stable to small perturbations, but, given a large enough initial perturbation, it transitions to a turbulent state. A scenario for such a transition is proposed and supported by numerical results: close to threshold, the nonlinear saturated state and the associated anomalous heat transport are dominated by long-lived coherent structures, which drift across the domain, have finite amplitudes, but are not volume filling; as the system is taken away from the threshold into the more unstable regime, the number of these structures increases until they overlap and a more conventional chaotic state emerges. Whereas this appears to represent a new scenario for transition to turbulence in tokamak plasmas, it is reminiscent of the behaviour of other subcritically turbulent systems, e.g. pipe flows and Keplerian magnetorotational accretion flows.Comment: 16 pages, 5 figures, accepted to Journal of Plasma Physic

    Ion-scale turbulence in MAST: anomalous transport, subcritical transitions, and comparison to BES measurements

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    We investigate the effect of varying the ion temperature gradient (ITG) and toroidal equilibrium scale sheared flow on ion-scale turbulence in the outer core of MAST by means of local gyrokinetic simulations. We show that nonlinear simulations reproduce the experimental ion heat flux and that the experimentally measured values of the ITG and the flow shear lie close to the turbulence threshold. We demonstrate that the system is subcritical in the presence of flow shear, i.e., the system is formally stable to small perturbations, but transitions to a turbulent state given a large enough initial perturbation. We propose that the transition to subcritical turbulence occurs via an intermediate state dominated by low number of coherent long-lived structures, close to threshold, which increase in number as the system is taken away from the threshold into the more strongly turbulent regime, until they fill the domain and a more conventional turbulence emerges. We show that the properties of turbulence are effectively functions of the distance to threshold, as quantified by the ion heat flux. We make quantitative comparisons of correlation lengths, times, and amplitudes between our simulations and experimental measurements using the MAST BES diagnostic. We find reasonable agreement of the correlation properties, most notably of the correlation time, for which significant discrepancies were found in previous numerical studies of MAST turbulence.Comment: 67 pages, 37 figures. Submitted to PPC

    The initial impact of the COVID-19 pandemic on the diagnosis of new cancers at a large pathology laboratory in the public health sector, Western Cape Province, South Africa

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    Background. The COVID-19 pandemic has disrupted cancer diagnostic services. A decline in the number of new cancers being diagnosed over a relatively short term implies a delay in diagnosis and subsequent treatment. This delay is expected to have a negative effect on cancerrelated morbidity and mortality. The impact of the pandemic on the number of new cancer diagnoses in our setting is unknown.Objectives. To assess the impact of COVID-19 on the number of new cancers diagnosed at our institution in the first 3 months following the implementation of lockdown restrictions, by focusing on common non-cutaneous cancers.Methods. A retrospective laboratory-based audit was performed at a large anatomical pathology laboratory in Western Cape Province, South Africa. The numbers of new diagnoses for six common cancers (breast, prostate, cervix, large bowel, oesophagus and stomach) from 1 April 2020 to 30 June 2020 were compared with the corresponding period in 2019.Results. Histopathological diagnoses for the six cancers combined decreased by 193 (–36.3%), from 532 new cases in the 2019 study period to 339 in the corresponding period in 2020. Substantial declines were seen for prostate (–58.2%), oesophageal (–44.1%), breast (–32.9%), gastric (–32.6%) and colorectal cancer (–29.2%). The smallest decline was seen in cervical cancer (–7%). New breast cancers diagnosed by cytopathology declined by 61.1%.Conclusions. The first wave of the COVID-19 pandemic and the associated response resulted in a substantial decline in the number of new cancer diagnoses, implying a delay in diagnosis. Cancer-related morbidity and mortality is expected to rise as a result, with the greatest increase in mortality expected from breast and colorectal cancer

    The effect of carbohydrate dose and timing on timed effort and time to exhaustion within a simulated cycle race in male professional cyclists

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    A key performance limitation affecting professional endurance cycling is carbohydrate storage and utilisation (Pöchmüller, Schwingshack, Colombani & Hoffmann, 2016, Journal of the International Society of Sports Nutrition, 13). Muscle glycogen stores alone are inefficient at maintaining optimal blood glucose levels beyond two hours of exercise; consequently, exogenous CHO is commonly used to counteract this (Jeukendrup, 2011, Journal of Sports Sciences, 21, 91-99). High concentrations of CHO can cause drops in blood glucose, excessive glycogen utilisation and gastrointestinal discomfort (GID) (Jeukendrup, 2011). Therefore, the aim of this study was to determine if frequent, smaller CHO feedings would be preferable to large, bolus CHO feedings on time trial cycling performance. With institutional ethics approval, 5 professional cyclists completed a 4h simulated cycle ride with 3 timed efforts in a randomised, cross-over, double blind design study. Each timed effort occurred in the last 10 min of each hour (TE1, TE2, TE3); participants were asked to cycle with maximum effort for this time. There was also a final effort at the end of the 4th hour to replicate a sprint finish. This was measured as time to exhaustion (TTE). Two interventions were used; a frequent feed (F) where participants drank 20g maltodextrin in 300ml flavoured water solution 3 times per hour and a bolus feed (B) where participants drank 60g maltodextrin solution once per hour. Heart rate, power output, GID, perceived exertion (RPE), blood lactate and blood glucose were recorded before and after TE1, TE2, TE3 and TTE. Wilcoxen signed rank test and Cohen’s D was performed to study differences between interventions and effect sizes.In the F intervention, average watts were significantly higher at TE2 (P<0.05 d=0.75) and TE3 (P<0.05 d=1.21) and the RPE was lower TE1 (P≥0.05 d=1.12), TE2 (P<0.05, d=1.12) and TTE (P≥0.05 d=1.12) compared to B. There was no significant difference between any other variables. The results suggest that despite power output being higher, RPE was lower in the F intervention. Gut absorption of CHO is limited to 1g/h (Jeukendrup, 2011), which may help explain these findings. This is one of the first studies to look at concentration and timing of CHO consumption in endurance cycling. Regular feeds of 20g CHO may be more beneficial on power output and RPE in endurance cycling compared to hourly 60g feeds

    Combined assessment (aspiration cytology and mammography) of clinically suspicious breast masses

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    We examined the safety and utility of the combined assessment of aspiration cytology and mammography in 705 women who had clinically suspicious or malignant palpable breast masses. Histological assessment confirmed 176 benign and 529 malignant lesions. There were no incorrect (false positive) diagnoses made in the 176 benign masses when combined assessment was used (specificity 1,0; predictive value 0,86); in isolation, however, there was a false positive cytological diagnosis («papillary carcinoma») and 3 false positive mammographic diagnoses. Benign disease (false negative) was incorrectly diagnosed by combined assessment in 4 of the 529 malignant masses (sensitivity 0,99; predictive value 0,98): cytological diagnoses were of fat necrosis (2) and benign cells on cytospin (1) and aspiration biopsy (1); mammographic diagnoses were of benign disease (2) and normality (2). Indeterminate («atypical», «suspicious») diagnoses were problematic and frequent (overall 223 (31,6%), malignant masses 137 (25,9%), benign masses 86 (48,9%); cytology 117 (16,6%), mammography 141 (20%). Thus, with the combined assessment of mammography and cytology in clinically suspicious breast masses, a decisive diagnosis was made in about two-thirds of cases allowing the safe commencement of therapy; the balance of patients required cone or excision biopsy

    GLAcier Feature Tracking testkit (GLAFT): a statistically and physically based framework for evaluating glacier velocity products derived from optical satellite image feature tracking

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    Glacier velocity measurements are essential to understand ice flow mechanics, monitor natural hazards, and make accurate projections of future sea-level rise. Despite these important applications, the method most commonly used to derive glacier velocity maps, feature tracking, relies on empirical parameter choices that rarely account for glacier physics or uncertainty. Here we test two statistics- and physics-based metrics to evaluate velocity maps derived from optical satellite images of Kaskawulsh Glacier, Yukon, Canada, using a range of existing feature-tracking workflows. Based on inter-comparisons with ground truth data, velocity maps with metrics falling within our recommended ranges contain fewer erroneous measurements and more spatially correlated noise than velocity maps with metrics that deviate from those ranges. Thus, these metric ranges are suitable for refining feature-tracking workflows and evaluating the resulting velocity products. We have released an open-source software package for computing and visualizing these metrics, the GLAcier Feature Tracking testkit (GLAFT).</p
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