366 research outputs found

    Fast Quantum Modular Exponentiation

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    We present a detailed analysis of the impact on modular exponentiation of architectural features and possible concurrent gate execution. Various arithmetic algorithms are evaluated for execution time, potential concurrency, and space tradeoffs. We find that, to exponentiate an n-bit number, for storage space 100n (twenty times the minimum 5n), we can execute modular exponentiation two hundred to seven hundred times faster than optimized versions of the basic algorithms, depending on architecture, for n=128. Addition on a neighbor-only architecture is limited to O(n) time when non-neighbor architectures can reach O(log n), demonstrating that physical characteristics of a computing device have an important impact on both real-world running time and asymptotic behavior. Our results will help guide experimental implementations of quantum algorithms and devices.Comment: to appear in PRA 71(5); RevTeX, 12 pages, 12 figures; v2 revision is substantial, with new algorithmic variants, much shorter and clearer text, and revised equation formattin

    Working with bipolar disorder during the covid-19 pandemic: Both crisis and opportunity

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    © 2020, WikiJournal User Group. All rights reserved. Beyond public health and economic costs, the COVID-19 pandemic adds strain, disrupts daily routines, and com-plicates mental health and medical service delivery for those with mental health and medical conditions. Bipolar disorder can increase vulnerability to infection; it can also enhance stress, complicate treatment, and heighten interpersonal stigma. Yet there are successes when people proactively improve social connections, prioritize self-care, and learn to use mobile and telehealth effectively

    Modeling Gravitational Recoil Using Numerical Relativity

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    We review the developments in modeling gravitational recoil from merging black-hole binaries and introduce a new set of 20 simulations to test our previously proposed empirical formula for the recoil. The configurations are chosen to represent generic binaries with unequal masses and precessing spins. Results of these simulations indicate that the recoil formula is accurate to within a few km/s in the similar mass-ratio regime for the out-of-plane recoil.Comment: corrections to text, 11 pages, 1 figur

    Security governance and networks: New theoretical perspectives in transatlantic security

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    The end of the Cold War has not only witnessed the rise of new transnational threats such as terrorism, crime, proliferation and civil war; it has also seen the growing role of non-state actors in the provision of security in Europe and North America. Two concepts in particular have been used to describe these transformations: security governance and networks. However, the differences and potential theoretical utility of these two concepts for the study of contemporary security have so far been under-examined. This article seeks to address this gap. It proposes that security governance can help to explain the transformation of Cold War security structures, whereas network analysis is particularly useful for understanding the relations and interactions between public and private actors in the making and implementation of national and international security policies

    Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys

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    Background: The gap between demand and supply of kidneys for transplantation necessitates the use of kidneys from extended criteria donors. Transplantation of these donor kidneys is associated with inferior results, reflected by an increased risk of delayed graft function. Inferior results might be explained by the higher immunogenicity of extended criteria donor kidneys. Normothermic machine perfusion (NMP) could be used as a platform to assess the quality and function of donor kidneys. In addition, it could be useful to evaluate and possibly alter the immunological response of donor kidneys. In this study, we first evaluated whether complement was activated during NMP of porcine and human discarded kidneys. Second, we examined the relationship between complement activation and pro-inflammatory cytokines during NMP. Third, we assessed the effect of complement activation on renal function and injury during NMP of porcine kidneys. Lastly, we examined local complement C3d deposition in human renal biopsies after NMP. Methods: NMP with a blood-based perfusion was performed with both porcine and discarded human kidneys for 4 and 6 h, respectively. Perfusate samples were taken every hour to assess complement activation, pro-inflammatory cytokines and renal function. Biopsies were taken to assess histological injury and complement deposition. Results: Complement activation products C3a, C3d, and soluble C5b-9 (sC5b-9) were found in perfusate samples taken during NMP of both porcine and human kidneys. In addition, complement perfusate levels positively correlated with the cytokine perfusate levels of IL-6, IL-8, and TNF during NMP of porcine kidneys. Porcine kidneys with high sC5b-9 perfusate levels had significantly lower creatinine clearance after 4 h of NMP. In line with these findings, high complement perfusate levels were seen during NMP of human discarded kidneys. In addition, kidneys retrieved from brain-dead donors had significantly higher complement perfusate levels during NMP than kidneys retrieved from donors after circulatory death. Conclusion: Normothermic kidney machine perfusion induces complement activation in porcine and human kidneys, which is associated with the release of pro-inflammatory cytokines and in porcine kidneys with lower creatinine clearance. Complement inhibition during NMP might be a promising strategy to reduce renal graft injury and improve graft function prior to transplantation

    Path Selection for Quantum Repeater Networks

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    Quantum networks will support long-distance quantum key distribution (QKD) and distributed quantum computation, and are an active area of both experimental and theoretical research. Here, we present an analysis of topologically complex networks of quantum repeaters composed of heterogeneous links. Quantum networks have fundamental behavioral differences from classical networks; the delicacy of quantum states makes a practical path selection algorithm imperative, but classical notions of resource utilization are not directly applicable, rendering known path selection mechanisms inadequate. To adapt Dijkstra's algorithm for quantum repeater networks that generate entangled Bell pairs, we quantify the key differences and define a link cost metric, seconds per Bell pair of a particular fidelity, where a single Bell pair is the resource consumed to perform one quantum teleportation. Simulations that include both the physical interactions and the extensive classical messaging confirm that Dijkstra's algorithm works well in a quantum context. Simulating about three hundred heterogeneous paths, comparing our path cost and the total work along the path gives a coefficient of determination of 0.88 or better.Comment: 12 pages, 8 figure

    Method to estimate ISCO and ring-down frequencies in binary systems and consequences for gravitational wave data analysis

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    Recent advances in the description of compact binary systems have produced gravitational waveforms that include inspiral, merger and ring-down phases. Comparing results from numerical simulations with those of post-Newtonian (PN), and related, expansions has provided motivation for employing PN waveforms in near merger epochs when searching for gravitational waves and has encouraged the development of analytic fits to full numerical waveforms. The models and simulations do not yet cover the full binary coalescence parameter space. For these yet un-simulated regions, data analysts can still conduct separate inspiral, merger and ring-down searches. Improved knowledge about the end of the inspiral phase, the beginning of the merger, and the ring-down frequencies could increase the efficiency of both coherent inspiral-merger-ring-down (IMR) searches and searches over each phase separately. Insight can be gained for all three cases through a recently presented theoretical calculation, which, corroborated by the numerical results, provides an implicit formula for the final spin of the merged black holes, accurate to within 10% over a large parameter space. Knowledge of the final spin allows one to predict the end of the inspiral phase and the quasinormal mode ring-down frequencies, and in turn provides information about the bandwidth and duration of the merger. In this work we will discuss a few of the implications of this calculation for data analysis.Comment: Added references to section 3 14 pages 5 figures. Submitted to Classical and Quantum Gravit

    Exact boundary conditions in numerical relativity using multiple grids: scalar field tests

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    Cauchy-Characteristic Matching (CCM), the combination of a central 3+1 Cauchy code with an exterior characteristic code connected across a time-like interface, is a promising technique for the generation and extraction of gravitational waves. While it provides a tool for the exact specification of boundary conditions for the Cauchy evolution, it also allows to follow gravitational radiation all the way to infinity, where it is unambiguously defined. We present a new fourth order accurate finite difference CCM scheme for a first order reduction of the wave equation around a Schwarzschild black hole in axisymmetry. The matching at the interface between the Cauchy and the characteristic regions is done by transfering appropriate characteristic/null variables. Numerical experiments indicate that the algorithm is fourth order convergent. As an application we reproduce the expected late-time tail decay for the scalar field.Comment: 14 pages, 5 figures. Included changes suggested by referee

    Characteristic extraction in numerical relativity: binary black hole merger waveforms at null infinity

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    The accurate modeling of gravitational radiation is a key issue for gravitational wave astronomy. As simulation codes reach higher accuracy, systematic errors inherent in current numerical relativity wave-extraction methods become evident, and may lead to a wrong astrophysical interpretation of the data. In this paper, we give a detailed description of the Cauchy-characteristic extraction technique applied to binary black hole inspiral and merger evolutions to obtain gravitational waveforms that are defined unambiguously, that is, at future null infinity. By this method we remove finite-radius approximations and the need to extrapolate data from the near zone. Further, we demonstrate that the method is free of gauge effects and thus is affected only by numerical error. Various consistency checks reveal that energy and angular momentum are conserved to high precision and agree very well with extrapolated data. In addition, we revisit the computation of the gravitational recoil and find that finite radius extrapolation very well approximates the result at \scri. However, the (non-convergent) systematic differences to extrapolated data are of the same order of magnitude as the (convergent) discretisation error of the Cauchy evolution hence highlighting the need for correct wave-extraction.Comment: 41 pages, 8 figures, 2 tables, added references, fixed typos. Version matches published version

    The Samurai Project: verifying the consistency of black-hole-binary waveforms for gravitational-wave detection

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    We quantify the consistency of numerical-relativity black-hole-binary waveforms for use in gravitational-wave (GW) searches with current and planned ground-based detectors. We compare previously published results for the (=2,m=2)(\ell=2,| m | =2) mode of the gravitational waves from an equal-mass nonspinning binary, calculated by five numerical codes. We focus on the 1000M (about six orbits, or 12 GW cycles) before the peak of the GW amplitude and the subsequent ringdown. We find that the phase and amplitude agree within each code's uncertainty estimates. The mismatch between the (=2,m=2)(\ell=2,| m| =2) modes is better than 10310^{-3} for binary masses above 60M60 M_{\odot} with respect to the Enhanced LIGO detector noise curve, and for masses above 180M180 M_{\odot} with respect to Advanced LIGO, Virgo and Advanced Virgo. Between the waveforms with the best agreement, the mismatch is below 2×1042 \times 10^{-4}. We find that the waveforms would be indistinguishable in all ground-based detectors (and for the masses we consider) if detected with a signal-to-noise ratio of less than 14\approx14, or less than 25\approx25 in the best cases.Comment: 17 pages, 9 figures. Version accepted by PR
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