'SO STONED' : common sense approach of the dizzy patient

The history taking of a dizzy patient is of utmost importance in order to differentiate the possible etiologies of vertigo. The key factors that allow a first approximation of diagnosis identification are based on the time profile, symptom profile, and trigger profile of the disease. Here, the proposed mnemonic "SO STONED" comprises eight different dimensions that characterize the vertigo-related complaints of the patient and guide the clinician in his or her decision scheme. All the letters "SO STONED" have a specific meaning: Symptoms, Often (Frequency), Since, Trigger, Otology, Neurology, Evolution, and Duration. Since the most common vestibular diseases have different fingerprints when all dimensions are considered, this tool can facilitate the identification of the appropriate vestibular diagnosis

Investigations on vinylene carbonate. IV. Radiation induced graft copolymerization of vinylene carbonate and N-vinyl-N-methylacetamide onto polyethylene films

Graft copolymerization of binary mixtures of vinylene carbonate (VCA) and N-vinyl-N-methylacetamide (VIMA) onto low density polyethylene (LDPE) films was studied by the mutual γ-irradiation technique. Sufficient amounts of functionally active VCA groups could be grafted onto the surface and the hydrophilicity of the surface was also improved. The grafting of VCA onto polyethylene films in the binary solutions was found to be promoted by the presence of VIMA, thus showing a positive synergism. The VCA content in the graft copolymers was always higher than in the copolymers obtained by homogeneous copolymerization using the same monomer feed composition. The monomer reactivity ratios, as well as a preferential partitioning of the monomers surrounding the polymeric substrate, were considered to explain the grafting reactions in the binary systems

Can the magnetic field in the Orion arm inhibit the growth of instabilities in the bow shock of Betelgeuse?

Many evolved stars travel through space at supersonic velocities, which leads to the formation of bow shocks ahead of the star where the stellar wind collides with the interstellar medium (ISM). Herschel observations of the bow shock of $\alpha$-Orionis show that the shock is almost free of instabilities, despite being, at least in theory, subject to both Kelvin-Helmholtz and Rayleigh-Taylor instabilities. A possible explanation for the lack of instabilities lies in the presence of an interstellar magnetic field. We wish to investigate whether the magnetic field of the interstellar medium (ISM) in the Orion arm can inhibit the growth of instabilities in the bow shock of $\alpha$-Orionis. We used the code MPI-AMRVAC to make magneto-hydrodynamic simulations of a circumstellar bow shock, using the wind parameters derived for $\alpha$-Orionis and interstellar magnetic field strengths of $B\,=\,1.4,\, 3.0$, and $5.0\, \mu$G, which fall within the boundaries of the observed magnetic field strength in the Orion arm of the Milky Way. Our results show that even a relatively weak magnetic field in the interstellar medium can suppress the growth of Rayleigh-Taylor and Kelvin-Helmholtz instabilities, which occur along the contact discontinuity between the shocked wind and the shocked ISM. The presence of even a weak magnetic field in the ISM effectively inhibits the growth of instabilities in the bow shock. This may explain the absence of such instabilities in the Herschel observations of $\alpha$-Orionis.Comment: 5 pages, including 7 figures. The published version will include 4 animations. Accepted for publication in A&

Indispensability arguments in favour of reductive explanations

Instances of explanatory reduction are often advocated on metaphysical grounds; given that the only real things in the world are subatomic particles and their interaction, we have to try to explain everything in terms of the laws of physics. In this paper, we show that explanatory reduction cannot be defended on metaphysical grounds. Nevertheless, indispensability arguments for reductive explanations can be developed, taking into account actual scientific practice and the role of epistemic interests. Reductive explanations might be indispensable to address some epistemic interest answering a specific explanation-seeking question in the most accurate, adequate and efficient way. Just like explanatory pluralists often advocate the indispensability of higher levels of explanation pointing at the pragmatic value of the explanatory information obtained on these higher levels, we argue that explanatory reduction – traditionally understood as the contender of pluralism – can be defended in a similar way. The pragmatic value reductionist, lower level explanations might have in the biomedical sciences and the social sciences is illustrated by some case studies

Investigations on vinylene carbonate. V. Immobilization of alkaline phosphatase onto LDPE films cografted with vinylene carbonate and N-vinyl-N-methylacetamide

Low-density polyethylene (LDPE) films cografted with vinylene carbonate (VCA) and N-vinyl-N-methylacetamide (VIMA) were studied as a matrix for the immobilization of the enzyme alkaline phosphatase (ALP) either by direct fixation or by inserting spacers. When water-soluble alkyldiamines such as diaminoethylene, diaminobutane, diethylenetriamine, and diaminohexane were used as spacers between the matrix and the enzyme, the surface concentration (SC) of the active ALP coupled on the matrix was increased, whereas the effect of the spacer on the SC was dependent on the length of the spacer. Bovine serum albumin (BSA) was preimmobilized onto the LDPE films to provide a better simulation of the biological environment for the enzyme, and the SC of ALP on the matrix was significantly increased by coupling ALP onto the BSA preimmobilized surfaces. Compared to native ALP, some physicochemical properties of ALP could be improved by the covalent immobilization

Wall forces on a sphere in a rotating liquid-filled cylinder

We experimentally study the behavior of a particle slightly denser than the surrounding liquid in solid body rotating flow. Earlier work revealed that a heavy particle has an unstable equilibrium point in unbounded rotation flows. In the confinement of the rotational flow by a cylindrical wall a heavy sphere with density 1.05 g/cm$^3$ describes an orbital motion in our experiments. This is due to the effect of the wall near the sphere, i.e. a repulsive force ($F_w$). We model $F_w$ on the sphere as a function of the distance from the wall ($L$): $F_W \propto L^{-4}$ as proposed by Takemura and Magnaudet (2003). Remarkably, the path from the model including $F_w$ reproduce the experimentally measured trajectory. In addition during an orbital motion the particle does not spin around its axis, and we provide a possible explanation for this phenomenon.Comment: 11 pages, 11 figure

Approximation in stochastic integer programming

Approximation algorithms are the prevalent solution methods in the field of stochastic programming. Problems in this field are very hard to solve. Indeed, most of the research in this field has concentrated on designing solution methods that approximate the optimal solutions. However, efficiency in the complexity theoretical sense is usually not taken into account. Quality statements mostly remain restricted to convergence to an optimal solution without accompanying implications on the running time of the algorithms for attaining more and more accurate solutions. However, over the last twenty years also some studies on performance analysis of approximation algorithms for stochastic programming have appeared. In this direction we find both probabilistic analysis and worst-case analysis. There have been studies on performance ratios and on absolute divergence from optimality. Only recently the complexity of stochastic programming problems has been addressed, indeed confirming that these problems are harder than most combinatorial optimization problems.