Significance of the pericardium in human subjects: Effects on left ventricular volume, pressure and ejection

To assess the effect of the pericardium, left ventricular systolic function and diastolic compliance were studied in 15 patients before and after pericardiotomy during coronary artery surgery. Using first pass radionuclide angiography, curves for left ventricular systolic function (stroke work versus end-diastolic volume) and a measure of diastolic compliance (pulmonary capillary wedge pressure versus end-diastolic volume) were generated by changing body position to alter venous return. Left ventricular end-diastolic volume ranged from 41 to 111 ml/m2and pulmonary capillary wedge pressure from 0 to 24 mm Hg.No significant changes were found in blood pressure (150/83 to 148/82 mm Hg), heart rate (66.7 to 67.1 beats/min), cardiac index (2.38 to 2.41 liters/min per m2), ejection fraction (0.56 to 0.54), end-systolic volume index (31.4 to 32.2 ml/m2), end-diastolic volume index (65.9 to 69.5 ml/m2) or pulmonary capillary wedge pressure (7.5 to 7.3 mm Hg). The pericardium did not affect the curves relating stroke work and end-diastolic volume or those relating pulmonary capillary wedge pressure and end-diastolic volume. Thus, when filling pressure and volume are normal or only moderately elevated, the pericardium does not appear to affect left ventricular systolic function or diastolic compliance in patients

Individual differences in subphonemic sensitivity and phonological skills

open access articleMany studies have established a link between phonological abilities (indexed by phonological awareness and phonological memory tasks) and typical and atypical reading development. Individuals who perform poorly on phonological assessments have been mostly assumed to have underspecified (or “fuzzy”) phonological representations, with typical phonemic categories, but with greater category overlap due to imprecise encoding. An alternative posits that poor readers have overspecified phonological representations, with speech sounds perceived allophonically (phonetically distinct variants of a single phonemic category). On both accounts, mismatch between phonological categories and orthography leads to reading difficulty. Here, we consider the implications of these accounts for online speech processing. We used eye tracking and an individual differences approach to assess sensitivity to subphonemic detail in a community sample of young adults with a wide range of reading-related skills. Subphonemic sensitivity inversely correlated with meta-phonological task performance, consistent with overspecification

Treatment of Periodontitis by Local Administration of Minocycline Microspheres: A Controlled Trial

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141491/1/jper1535.pd

A Proposal to Improve Performance of the Forest Vegetation Simulator - Fire and Fuels Extension

The Forest Vegetation Simulator (FVS) and its associated Fire and Fuels Extension (FFE) have been used to provide information required by larger software systems like the Interagency Fuels Treatment - Decision Support System (IFT-DSS). Interacting with FVS in an automated fashion has been difficult, and simulations with very large numbers of stands, such as those necessary for landscape analyses for fire planning, could take a significant amount of time to process. This project was designed to: (A) develop a requirements document considering Service Oriented Architecture and how that may apply to FVS, and how FVS will be used interactively; (B) profile the FVS code to evaluate what takes the most processing time and identify possible areas for program optimization; (C) while optimizing and reducing the size of code, migrate FVS to a modern development framework such as Intel Fortran and the Visual Studio IDE; (D) identify platforms and systems that meet needs of the JFSP and other stakeholders, such as creating dynamic link libraries (DLL); and (E) specify and define the use of new technologies in the next phase of software development, such as OpenMP directives, thus implementing multithreading in the base FVS executables or extensions to take advantage of increased computing power of multicore processors