The Steady Boundary Layer due to a Fast Vortex

A point vortex located above and convected parallel to a wall is an important model of the process by which a boundary layer becomes unstable due to external disturbances. Often it has been assumed that the boundary layer due to the passage of the vortex is inherently unsteady. Here we show that for a vortex convected by a uniform shear flow, there is a steady solution when the speed of the vortex cv is sufficiently fast. The existence of the steady solution is demonstrated analytically in the limit of large vortex velocity (cv→∞) and numerically at more moderate speeds. This solution may provide a useful base state about which to investigate the stability of a boundary layer induced by external disturbances

The impact of loco-regional recurrences on metastatic progression in early-stage breast cancer: a multistate model

To study whether the effects of prognostic factors associated with the occurrence of distant metastases (DM) at primary diagnosis change after the incidence of loco-regional recurrences (LRR) among women treated for invasive stage I or II breast cancer. The study population consisted of 3,601 women, enrolled in EORTC trials 10801, 10854, or 10902 treated for early-stage breast cancer. Data were analysed in a multivariate, multistate model by using multivariate Cox regression models, including a state-dependent covariate. The presence of a LRR in itself is a significant prognostic risk factor (HR: 3.64; 95%-CI: 2.02-6.5) for the occurrence of DM. Main prognostic risk factors for a DM are young age at diagnosis (</=40: HR: 1.79; 95%-CI: 1.28-2.51), larger tumour size (HR: 1.58; 95%-CI: 1.35-1.84) and node positivity (HR: 2.00; 95%-CI: 1.74-2.30). Adjuvant chemotherapy is protective for a DM (HR: 0.66; 95%-CI: 0.55-0.80). After the occurrence of a LRR the latter protective effect has disappeared (P = 0.009). The presence of LRR in itself is a significant risk factor for DM. For patients who are at risk of developing LRR, effective local control should be the main target of therapy

Nontrivial Polydispersity Exponents in Aggregation Models

We consider the scaling solutions of Smoluchowski's equation of irreversible aggregation, for a non gelling collision kernel. The scaling mass distribution f(s) diverges as s^{-tau} when s->0. tau is non trivial and could, until now, only be computed by numerical simulations. We develop here new general methods to obtain exact bounds and good approximations of $\tau$. For the specific kernel KdD(x,y)=(x^{1/D}+y^{1/D})^d, describing a mean-field model of particles moving in d dimensions and aggregating with conservation of ``mass'' s=R^D (R is the particle radius), perturbative and nonperturbative expansions are derived. For a general kernel, we find exact inequalities for tau and develop a variational approximation which is used to carry out the first systematic study of tau(d,D) for KdD. The agreement is excellent both with the expansions we derived and with existing numerical values. Finally, we discuss a possible application to 2d decaying turbulence.Comment: 16 pages (multicol.sty), 6 eps figures (uses epsfig), Minor corrections. Notations improved, as published in Phys. Rev. E 55, 546

The nucleation behavior of supercooled water vapor in helium

The nucleation behavior of supersaturated water vapor in helium is experimentally investigated in the temperature range of 200–240 K. The experiments are performed using a pulse expansion wave tube. The experimental results show a sharp transition in the nucleation rates at 207 K. We suggest that the transition is due to the transition of vapor/liquid to vapor/solid nucleation (ordered with decreasing temperature). A qualitative theoretical explanation is given based on the classical nucleation theory and the surface energy of ice

Analysis of linearized inverse problems in ultrasound transmission imaging

The purpose of this paper is to analyze the linearized inverse problem during the iterativesolution process of the ill-posed nonlinear inverse problem of image reconstruction for ultra-sound transmission imaging. We show that the conjugate gradient applied to normal equation(CGNE) method gives more reliable solutions for linearized systems than Tikhonov regular-ization methods. The linearized systems are more sensitive when treated by CGNE than byTikhonov regularization methods. The Tikhonov regularization is less effective at the be-ginning of the outer-loop iteration, where the nonlinearity is dominating while the conjugategradient for the linearized system stops earlier. Only when the linear approximation is goodenough to describe the whole system, Tikhonov regularization can fully play its role and giveslightly better reconstruction results as compared to CGNE in a very noisy case

XES tools

Process mining has emerged as a new way to analyze business processes based on event logs. These events logs need to be extracted from operational systems and can subsequently be used to discover or check the conformance of processes. ProM is a widely used tool for process mining. In earlier versions of ProM, MXML was used as an input format. In future releases of ProM, a new logging format will be used: The eXtensible Event Stream (XES) format. This format has several advantages over MXML. The paper presents two tools that use this format - XESMa and ProM6 - and highlights the main innovations and the role of XES. XESMa enables domain experts to specify how the event log should be extracted from existing systems and converted to XES. ProM6 is a completely new process mining framework based on XES and enabling innovative process mining functionality.</p

Kinetic Anomalies in Addition-Aggregation Processes

We investigate irreversible aggregation in which monomer-monomer, monomer-cluster, and cluster-cluster reactions occur with constant but distinct rates K_{MM}, K_{MC}, and K_{CC}, respectively. The dynamics crucially depends on the ratio gamma=K_{CC}/K_{MC} and secondarily on epsilon=K_{MM}/K_{MC}. For epsilon=0 and gamma<2, there is conventional scaling in the long-time limit, with a single mass scale that grows linearly in time. For gamma >= 2, there is unusual behavior in which the concentration of clusters of mass k, c_k decays as a stretched exponential in time within a boundary layer k<k* propto t^{1-2/gamma} (k* propto ln t for gamma=2), while c_k propto t^{-2} in the bulk region k>k*. When epsilon>0, analogous behaviors emerge for gamma<2 and gamma >= 2.Comment: 6 pages, 2 column revtex4 format, for submission to J. Phys.