A transobturator adjustable system for male incontinence: 30-month follow-up of a multicenter study

Purpose To report long-term results of the Argus T adjustable system for treatment of post-prostatectomy urinary incontinence (PPI). Materials and Methods From October 2007 to August 2008, 37 patients with PPI were included in a prospective, single-arm, multicenter trial of treatment with the Argus T adjustable system (Promedon, Argentina). Preoperative evaluation included urine culture, urethrocystoscopy, urodynamic testing, 24-h pad weight test (PWT) and quality of life questionnaires. Patients were stratified according to baseline degree of incontinence (mild–moderate or severe). Postoperative evaluation included immediate PWT, quality of life questionnaires and daily use of pads at 1, 12 and 30 months. Results and Conclusions One patient was lost to follow-up. At the 30-month follow-up, 24/31 patients (77%) were dry, 3/31 (10%) improved and 4/31 (13%) were failures. In particular, in the mild-moderate group, 8/8 (100%) patients were dry. In the severe group, 20/28 patients (71%) were dry, 3/28 (11%) improved and 5/28 (18%) were failures. Median visual analogue scale (VAS) scores dropped from 9 (4-10) to 0.5 (0-10) and International Consultation on Incontinence Questionnaire Short Form scores from (ICIQ-SF) 19 (12–21) to 1 (0–10). Retrograde leak point pressure increased from 18 (5–29) to 35 (22–45) cm H2O after intraoperative adjustment. Complications included immediate postoperative infection in 2/36 patients (6%) and transient inguinal and/or perineal pain in 22/36 patients (61%). Argus T has a long-term high success rate (86% cure + improvement at the 30-month follow-up). Good outcomes were achieved even in severe incontinence cases and maintained for over 30 months

Mirabegron to manage symptoms of interstitial cystitis / bladder pain syndrome: A stone for two birds?

Background: Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS) patients often experience lowered quality of life due to pain, urinary urgency, and increases in urinary frequency. Like many chronic pain disorders, IC/BPS is poorly understood and treatment unsatisfactory.&nbsp;Materials and methods: We prospectively monitored the effects on pain and urinary complaints, of mirabegron associated with amitriptyline, for randomly selected women with IC/BPS.&nbsp;Results: Twenty-five women were randomly selected to treat pain symptoms of IC/BPS and 12 followed up until the end of the study. All patients showed improvement on all questionnaires referring to pain IC/BPS symptoms and urinary storage symptoms. There was no statistically significant improvement in urinary frequency.&nbsp;Conclusions: We suggest that mirabegron can work controlling urinary urgency and pain of IC/BPS patients.</p

Retalho mediofrontal para reconstrução nasal

Introdução: O retalho mediofrontal foi descrito 600 anos antes de Cristo para a reconstrução nasal, mas é ainda muito utilizado na reconstrução das lesões nasais tumorais. Objetivo: Relatar a experiência de um serviço universitário de cirurgia plástica no uso desse retalho. Métodos: Foi realizado o estudo restrospectivo descritivo de uma série de 35 casos operados em período de dez anos e seis meses. Resultados: A idade média dos pacientes foi de 68,6 anos com predomínio do gênero masculino. O retalho mediofrontal foi utilizado para reconstrução após ressecção de tumores, sendo o carcinoma basocelular o mais frequente. Conclusões: O retalho mediofrontal representa a escolha ideal reconstrutiva para muitos pacientes com bom resultado estético e funcional

Suplementação nutricional, pretensões e custo entre jovens do interior e litoral paulista experiêntes em treinamento resistido

Objective and closed questions were applied to 15 - 21 years old individuals under regular resistance exercise practice and self-reported nutritional supplements users, approaching training practices, type of substance feed and socioeconomic characteristics. The data were treated by frequency around the mean value. Major difference was observed to the goal of improvement in physical fitness (Guaruja 21% and Bauru 9.6%), close to the muscle hypertrophic enhancements (Guaruja 22% and Bauru 19.2%), and health proposes (17.3%), which was only reported in the country city. The monthly employment with supplements was observed to be close to one hundred Real, in both regions (Guaruja 79% and Bauru 80%). Even, based on different purposes, the supplements feed practice was closed to the goals, showing a reliable referential of use, but done without appropriated professional care.Questões objetivas e fechadas foram aplicadas em jovens entre 15 a 21 anos praticantes regulares de exercícios resistidos e usuários de suplementos nutricionais, abrangendo perguntas sobre a prática esportiva, substâncias utilizadas e características socioeconômicas do indivíduo. Os dados foram apresentados em torno da frequência média de ocorrência. A maior diferença foi quanto à motivação pela melhora do condicionamento físico (Guarujá 21% e Bauru 9,6%), sendo a intenção de aumento da massa muscular a resposta mais próxima (Guarujá 22% e Bauru 19,2%), e a ênfase na Saúde mais relatada no Interior (17,3%). Ambas as regiões empregam até cem reais mensais no consumo (Guarujá 80% e Bauru 79%). Mesmo com diferentes propósitos, o consumo atende às pretensões relatadas, evidenciando bom referencial sem, contudo, usá-los sob supervisão profissional

Genome Sequence of "Candidatus Microthrix parvicella" Bio17-1, a Long-Chain-Fatty-Acid-Accumulating Filamentous Actinobacterium from a Biological Wastewater Treatment Plant

Candidatus Microthrix bacteria are deeply branching filamentous actinobacteria which occur at the water-air interface of biological wastewater treatment plants, where they are often responsible for foaming and bulking. Here, we report the first draft genome sequence of a strain from this genus: "Candidatus Microthrix parvicella" strain Bio17-1

The critical pathway for deceased donation:reportable uniformity in the approach to deceased donation

P>The critical pathway of deceased donation provides a systematic approach to the organ donation process, considering both donation after cardiac death than donation after brain death. The pathway provides a tool for assessing the potential of deceased donation and for the prospective identification and referral of possible deceased donors

Hiperlugares móviles. Actividades conectadas más allá del transporte

Este trabajo pretende estudiar y contribuir a la agenda académica y de gobierno alrededor de temas como la realidad de los nuevos espaciotiempos de la movilidad de bienes, información y personas; las transformaciones en la ocupación de los territorios; las múltiples dimensiones del espacio público y del espacio de trabajo, de la tecnología de la información y de los lugares y actividades conectadas. Para los ciudadanos, este es un momento crucial en el que se vienen modificando sus formas de acceder y apropiar el territorio, y representa un desafío en la transformación de sus prácticas cotidianas, de estudio, de trabajo e incluso de ocio; así como en la forma de relacionarse con los otros en sus distintos escenarios de interacción. Estos retos fueron explorados por un conjunto de investigadores de América Latina, quienes desde distintos enfoques consolidaron las principales reflexiones y experiencias de casos documentados a nivel conceptual y empírico e incluso testimoniales