Development of scientific understanding of the essence of the fiscal control in Russia over the past 100 years

The relevance of the studied problem is determined by the fact that the modern understanding of the essence of the fiscal control is based on the research of specific essential characteristics. As a rule, they are not of system nature and are not connected with studies of other characteristics. The aim of this article is a synthesis of the main theoretical achievements in the study of the fiscal control in the Russian Federation and other countries, and identifying of the most important characteristics, which allow to reveal its internal content. The leading approach to the research of this issue is the system approach that provides a means of analyzing the essence of the fiscal control as a multifaceted phenomenon of the economic life of economic entities and the state. The main results of the research consist in the substantiation of the three major theoretical outputs concerning: a) the nature of the fiscal control as an economic phenomenon; b) the main essential characteristics of the fiscal control; c) interested user in information of the fiscal control as the foundation of its organization and implementation.. The materials of this article can be used for further research of the theory and methodology of carrying out the fiscal control, as well as its organization on the macro and micro levels. © 2016 Valieva et al

Typology of strategies of personality meaning-making during professional education

The importance of the studied issue is conditioned by the fact that high dynamic of processes in the labour market requires constant work of an individual on self-determination and search for significance of his/her professional activity. The purpose of research is theoretical development and empirical verification of the types of strategies of meaning-making based on perceptions of future in terms of professional self-determination of the personality at the stage of vocational training. Basic research methods: modelling, psychosemantic approach, allowing to perform research process with the possibility of more in-depth analysis of the results. Research results: the model of the semantical future in the consciousness of the personality, which includes affective, cognitive, activity and intentional components is developed and empirically verified; the types of strategies of meaning-making based on perceptions of future in terms of professional selfdetermination of the personality at the stage of vocational training is identified, the typology includes the following 3 types of the meaning-making strategies: strategy of integration of the meaning of education and profession in the model of own future, strategy of disintegration and strategy of uncertainty and delay of the semantical choice. Significance of results: analysis of the semantical grounds for future professional activity will help optimize the training of a competent, competitive and adaptive specialist ready to continuous self-development, and to intensify the process of professional self-determination and building life and professional prospects of the personality at the stage of vocational training, as exactly at this stage the professional competence and identity is built up. © 2016 Shchipanova et al

Globalization and regionalization: Institution aspect

The urgency of the analyzed problem is due to the fact that regionalization and globalization have a dual nature and depend on the institutional system, which, in turn, affects the establishment of new rules in the economic space in which interact businesses. The purpose of the article is to justify the fact that the institutional aspect of globalization and regionalization is, above all, in the establishment of new rules and norms of the economy that affect all businesses, and one of the key roles is performed by innovation and investment institutions. The main methods in the study of this problem is the dialectical method, which allows identifying trends in the development institutions at the regional level. Results: the article proves that the development of modern market institutions is associated with the stimulation of innovation activity in the regions and the creation of innovation systems in them, the effectiveness of which depends on the degree of interconnectedness and interdependence of the national innovation system, which corresponds to the globalization processes. The data of the article may be useful in determining institutions of the Samara region that promote economic development and competitiveness of the region, as well as practical development of managerial decisions related to improving the efficiency of the use of economic and administrative resources. © 2016 Matveev et al

Impact of Echinococcosis on Quality of Sheep Meat in the South Eastern Kazakhstan

A survey of 2,123 slaughtered adult sheep in markets of the south-east Kazakhstan established that the average contamination of animals by Echinococcus granulosus is 9.1% with primary localization of cysts in livers and lungs. The histologic structure of the muscle tissue of infected sheep displayed destructive changes with a prevalence of granular dystrophy. The amount of protein, fat, calcium and energetical value of such meat considerably decreased. Besides in the muscle tissue of the animals infected with echinococcosis there was a substantial increase of humidity and amount of ash as well as qualitative and quantitative changes of the amino acids profile. Along with damage to the synthesis of proteins and sharp insufficiency of vitamins A, E, B1, and B2 there was a shift in a lipidic exchange that was expressed as a noticeable reduction in the level of monounsaturated and polyunsaturated fatty acids. The data support the conclusion that the meat from the sheep infected with echinococcosis is of inferior quality and quantity compared to that of healthy animals

Оценка влияния материнского генотипа на реализацию продуктивного потенциала голштинизированного скота в условиях Новосибирской области

An analysis of the productive qualities of mothers cows and their offspring, obtained from different fathers, showed that the contribution of parents to the formation of milk productivity is unequal. Intensive selection of bulls-producers leads to fixation of homozygotes at the loci associated with traits of milk production, which increases their influence on offspring. The strength of the influence of the father’s factor on milk yield, milk protein and live weight of daughters was 6, respectively; 14 and 16%. The productivity level of mothers did not significantly affect the productivity of their daughters. High-yielding offspring can be obtained from low-yielding cows. Daughters surpassed their mothers in milk yield, but inferior in fat milk. The proportion of deviation from the theoretically expected productivity of daughters (milk yield per 305 days), which is caused by the influence of the maternal genotype, in the groups of Auckland No. 426436885, Showman No. 831842 and Euclid No. 831491, respectively, was 15.8; 27.5 and 30.4%. The correlation coefficient between the milk yield of mothers and daughters was + 0.25 (p <0.05), and body weight correlated at the level of +0.3 (p <0.01). In the groups of daughters, butterfat is associated with milk yield (r = - 0.5) and milk protein (from +0.34 to +0.67). For mothers, the relationship between these indicators was lower. It is possible that half-siblings have stronger genetic links between traits than unrelated mothers. Genetic diversity in milk yield (h2 = 0.6) and live weight (h2 = 0.5) was established. Repeatability coefficients for fat and milk protein were at the level of 0.35. The productive potential of the breed depends on the combinational compatibility of the parents, their contribution to the formation of complex quantitative characteristics of productivity.Анализ продуктивных качеств коров-матерей и их потомков, полученных от разных отцов, показал, что вклад родителей в формирование молочной продуктивности неравноценен. Интенсивный отбор племенных быков ведёт к фиксации гомозигот по локусам, ассоциированным с признаками молочной продуктивности, что увеличивает их влияние на потомков. Сила влияния фактора отца на удой, белковомолочность и живую массу дочерей составила соответственно 6; 14 и 16%. Уровень продуктивности матерей не оказал существенного влияния на продуктивность дочерей. От низкопродуктивных коров можно получать высокоудойное потомство. Дочери по удою превосходили своих матерей, но уступали по жирномолочности. Доля отклонения от теоретически ожидаемой продуктивности дочерей (удой за 305 дней), которая вызвана влиянием материнского генотипа, в группах Окленда-М № 426436885, Шоумена № 831842 и Эвклида № 831491 составила соответственно 15,8; 27,5 и 30,4%. Коэффициент корреляции между удоем матерей и дочерей составил + 0,25 (р<0,05), а живая масса коррелировала на уровне +0,3 (р<0,01). В группах дочерей жирномолочность связана с удоем (r= – 0,5) и белковомолочностью (от +0,34 до +0,67). У матерей связь между этими показателями была ниже. Возможно, у полусибсов сильнее генетическое сцепление между признаками, чем у неродственных матерей. Установлено генетическое разнообразие по удою (h 2=0,6) и живой массе (h 2=0,5). Коэффициенты повторяемости по жирно- и белковомолочности были на уровне 0,35. Продуктивный потенциал породы зависит от комбинационной сочетаемости родителей, их вклада в формирование сложных количественных признаков продуктивности

2-AZINYL QUINAZOLINES: SYNTHESIS AND PHOTOPHYSICAL PROPERTIES

This work was supported by the Russian Scientific Foundation (project 22-23-00006)

Synthesis of New Phosphorylated 1,2,4-Triazole-3-thiones. N,S-Functionalization Methods

© 2018, Pleiades Publishing, Ltd. New phosphorylated 1,2,4-triazole-3-thiones have been synthesized, and the possibility of their N,Sfunctionalization has been demonstrated. The direction of alkylation of 1,2,4-triazole-3-thiones with ethyl acrylate has been shown to depend on the substituent on the N4 atom

Опыт применения тоцилизумаба у больной полиартикулярным вариантом ювенильного идиопатического артрита с поражением шейного отдела позвоночника

The article describes a case of polyarticular juvenile idiopathic arthritis lesions of the cervical spine. This clinical example demonstrates the high efficiency of tocilizumab in a patient with polyarticular juvenile idiopathic arthritis with lesions of the cervical spine. After the first injection of tocilizumab a decrease in the following was observed: pain in the cervical spine and affected joints, severity of functional disorders in the temporomandibular joint and the interphalangeal joints, cervical spine; a 30% improvement in the JADAS, ACRpedi30 was achieved. By the 8th week of therapy the proliferative changes in the joints of the hands and arthralgia decreased, as well as the duration of morning stiffness. After 3 months there was a decrease in the activity of Jia (DAS28), and the erythrocyte sedimentation rate and serum concentrations of C-reactive protein. Adverse effects during therapy with tocilizumab were not observed. The disease activity decreased, (assessed using the visual analog scale (VAS)), as well as the functional impairment (assessed using the Children Health Assessment Questionnaire (CHAQ)). The emotional status and quality of life of the child and her family improved significantly.В статье описан случай полиартикулярного варианта ювенильного идиопатического артрита с поражением суставов шеи и височно-нижнечелюстных суставов, рефрактерного к терапии классическим иммунодепрессантом. Представленный клинический пример демонстрирует высокую эффективность тоцилизумаба у пациентки с полиартикулярным ювенильным идиопатическим артритом, сопровождающимся поражением осевого скелета. Уже после первого введения тоцилизумаба отмечено уменьшение боли в шейном отделе позвоночника и пораженных суставах, снижение выраженности функциональных нарушений в височно-нижнечелюстных и межфаланговых суставах, шейном отделе позвоночника; достигнуто 30% улучшение по индексам JADAS, Американской коллегии ревматологов (ACRpedi30). К 8-й нед терапии у девочки уменьшились пролиферативные изменения в суставах кистей, артралгии, сократилась длительность утренней скованности. Через 3 мес отмечалось снижение активности ювенильного идиопатического артрита по индексу DAS28, а также скорости оседания эритроцитов и cывороточной концентрации С-реактивного белка. Нежелательных явлений на фоне терапии тоцилизумабом не отмечено. Снизилась активность болезни (по визуально-аналоговой шкале), уменьшилась функциональная недостаточность (по опроснику Children Health Assessment Questionnaire). Значительно улучшилось эмоциональное состояние и качество жизни ребенка и его семьи