Myocardial strain in healthy adults across a broad age range as revealed by cardiac magnetic resonance imaging at 1.5 and 3.0T: associations of myocardial strain with myocardial region, age, and sex

Purpose: We assessed myocardial strain using cine displacement encoding with stimulated echoes (DENSE) using 1.5T and 3.0T MRI in healthy adults. Materials and Methods: Healthy adults without any history of cardiovascular disease underwent MRI at 1.5T and 3.0T within 2 days. The MRI protocol included b-SSFP, 2D cine-EPI-DENSE, and late gadolinium enhancement in subjects>45 years. Acquisitions were divided into 6 segments, global and segmental peak longitudinal and circumferential strain were derived and analyzed by field strength, age and gender. Results: 89 volunteers (mean age 44.8 ± 18.0 years, range: 18-87 years) underwent MRI at 1.5T, and 88 of these subjects underwent MRI at 3.0T (1.4±1.4 days between the scans). Compared with 3.0T, the magnitudes of global circumferential (-19.5±2.6% vs. -18.47±2.6%; p=0.001) and longitudinal (-12.47±3.2% vs -10.53±3.1%; p=0.004) strain were greater at 1.5T. At 1.5T, longitudinal strain was greater in females than in males: -10.17±3.4% vs. -13.67±2.4%; p=0.001. Similar observations occurred for circumferential strain at 1.5T (-18.72±2.2% vs. -20.10±2.7%; p=0.014) and at 3.0T (-17.92 ± 1.8% vs -19.1 ± 3.1%; p=0.047). At 1.5T, longitudinal and circumferential strain were not associated with age after accounting for sex (longitudinal strain p= 0.178, circumferential strain p= 0.733). At 3.0T, longitudinal and circumferential strain were associated with age. (p<0.05) Longitudinal strain values were greater in the apico-septal, basal-lateral and mid-lateral segments and circumferential strain in the inferior, infero-lateral and antero-lateral LV segments. Conclusion: Myocardial strain parameters as revealed by cine-DENSE at different MRI field strengths were associated with myocardial region, age and sex

Petersen's Hernia after Mini (One Anastomosis) Gastric Bypass

info:eu-repo/semantics/publishedVersio

Feasibility of the REDCap platform for Single Center and Collaborative Multicenter CMR Research

REDCap (Research Enterprise Data CAPture) software may provide a feasible platform for CMR Centers to: a) capture clinical throughput securely for research purposes, and 2) collaborate using a common platform for either distributed or centralized data storage. REDCap may facilitate CMR Centers' participation in the research enterprise, especially those with limited resources. REDCap may catalyze multicenter studies with "distributed data collection" where CMR sites can clone shared data dictionaries across sites for subsequent compilation into a singular master data file

The global cardiovascular magnetic resonance registry (GCMR) of the society for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments

GCMR received seed funding from SCMR (SCMR_GRANT_001) for the development and maintenance of GCMR websites and database infrastructure

Subendocardial contractile impairment in chronic ischemic myocardium: assessment by strain analysis of 3T tagged CMR

<p>Abstract</p> <p>Background</p> <p>The purpose of this study was to quantify myocardial strain on the subendocardial and epicardial layers of the left ventricle (LV) using tagged cardiovascular magnetic resonance (CMR) and to investigate the transmural degree of contractile impairment in the chronic ischemic myocardium.</p> <p>Methods</p> <p>3T tagged CMR was performed at rest in 12 patients with severe coronary artery disease who had been scheduled for coronary artery bypass grafting. Circumferential strain (C-strain) at end-systole on subendocardial and epicardial layers was measured using the short-axis tagged images of the LV and available software (Intag; Osirix). The myocardial segment was divided into stenotic and non-stenotic segments by invasive coronary angiography, and ischemic and non-ischemic segments by stress myocardial perfusion scintigraphy. The difference in C-strain between the two groups was analyzed using the Mann-Whitney U-test. The diagnostic capability of C-strain was analyzed using receiver operating characteristics analysis.</p> <p>Results</p> <p>The absolute subendocardial C-strain was significantly lower for stenotic (-7.5 ± 12.6%) than non-stenotic segment (-18.8 ± 10.2%, p < 0.0001). There was no difference in epicardial C-strain between the two groups. Use of cutoff thresholds for subendocardial C-strain differentiated stenotic segments from non-stenotic segments with a sensitivity of 77%, a specificity of 70%, and areas under the curve (AUC) of 0.76. The absolute subendocardial C-strain was significantly lower for ischemic (-6.7 ± 13.1%) than non-ischemic segments (-21.6 ± 7.0%, p < 0.0001). The absolute epicardial C-strain was also significantly lower for ischemic (-5.1 ± 7.8%) than non-ischemic segments (-9.6 ± 9.1%, p < 0.05). Use of cutoff thresholds for subendocardial C-strain differentiated ischemic segments from non-ischemic segments with sensitivities of 86%, specificities of 84%, and AUC of 0.86.</p> <p>Conclusions</p> <p>Analysis of tagged CMR can non-invasively demonstrate predominant impairment of subendocardial strain in the chronic ischemic myocardium at rest.</p