51 research outputs found
Alterações do trato digestório de cães da raça Golden Retriever afetados pela distrofia muscular
Bounding separable recourse functions with limited distribution information
The recourse function in a stochastic program with recourse can be approximated by separable functions of the original random variables or linear transformations of them. The resulting bound then involves summing simple integrals. These integrals may themselves be difficult to compute or may require more information about the random variables than is available. In this paper, we show that a special class of functions has an easily computable bound that achieves the best upper bound when only first and second moment constraints are available.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44185/1/10479_2005_Article_BF02204821.pd
Efeito do nível de óleo de milho adicionado à dieta de eqüinos sobre a digestibilidade dos nutrientes
Can Monetary Policy be used to Influence the Real Value of the $A in the Short or Long Run?
Can Monetary Policy be used to Influence the Real Value of the $A in the Short or Long Run?
Financial Economics,
Part-based multi-frame registration for estimation of the growth of cellular networks in plant roots
Colloid Surface Chemistry Critically Affects Multiple Particle Tracking Measurements of Biomaterials
Characterization of the properties of complex biomaterials using microrheological techniques has the promise of providing fundamental insights into their biomechanical functions; however, precise interpretations of such measurements are hindered by inadequate characterization of the interactions between tracers and the networks they probe. We here show that colloid surface chemistry can profoundly affect multiple particle tracking measurements of networks of fibrin, entangled F-actin solutions, and networks of cross-linked F-actin. We present a simple protocol to render the surface of colloidal probe particles protein-resistant by grafting short amine-terminated methoxy-poly(ethylene glycol) to the surface of carboxylated microspheres. We demonstrate that these poly(ethylene glycol)-coated tracers adsorb significantly less protein than particles coated with bovine serum albumin or unmodified probe particles. We establish that varying particle surface chemistry selectively tunes the sensitivity of the particles to different physical properties of their microenvironments. Specifically, particles that are weakly bound to a heterogeneous network are sensitive to changes in network stiffness, whereas protein-resistant tracers measure changes in the viscosity of the fluid and in the network microstructure. We demonstrate experimentally that two-particle microrheology analysis significantly reduces differences arising from tracer surface chemistry, indicating that modifications of network properties near the particle do not introduce large-scale heterogeneities. Our results establish that controlling colloid-protein interactions is crucial to the successful application of multiple particle tracking techniques to reconstituted protein networks, cytoplasm, and cells
Studies on the Subcellular Organelles of Neutrophils in Chronic Granulocytic Leukaemia with Special Reference to Alkaline Phosphatase
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