23 research outputs found

    Scopolamine Administration Modulates Muscarinic, Nicotinic and NMDA Receptor Systems

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    Studies on the effect of scopolamine on memory are abundant but so far only regulation of the muscarinic receptor (M1) has been reported. We hypothesized that levels of other cholinergic brain receptors as the nicotinic receptors and the N-methyl-D-aspartate (NMDA) receptor, known to be involved in memory formation, would be modified by scopolamine administration

    Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

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