4,653 research outputs found
Pubertal development of penile Nitric Oxide Synthase (NOS)-containing nerve fibers in the rat
Objectives: To evaluate the expression of nitric oxide synthase (NOS)-containing nerve fibers in penile tissue in different age groups in the rat and to measure serum testosterone levels during this developmental process. Material and Methods: Fifteen male Sprague-Dawley (SD) rats divided into 3 equally numbered groups of different age (40 days (d), 54d and 65d) were used in this study. Penile erection was evaluated using cavernous nerve electrostimulation. Before sacrificing the rats, a penile midshaft specimen was taken for nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase staining and blood samples were collected to evaluate the testosterone levels. Results: Electrostimulation of the cavernous nerve revealed no significant difference in the maximal intracavernous pressure in the different age groups (44.9 ± 6.4, 54.8 ± 24.8, 45.9 ± 16.8 cm H2O, respectively; p>0.05), but the latency of the response to electrostimulation was significantly shorter in 54d and 65d than in 40d-old rats (5.4 ± 0.8 and 5.0 ± 0.7 vs. 9.0 ± 5.4 sec., respectively;
4-H Southern Swines Feral Hog Challenge
Estimates indicate that the population of feral hogs may exceed 500,000 in Florida. They have proven difficult to manage. Land managers in Florida reported that feral hogs were a significant problem that needed to be addressed. The UF/IFAS St. Lucie County Cooperative Extension conducted the 4-H Southern Swines Feral Hog Challenge to help land managers reduce feral hog populations in a cost-effective manner. This activity was conducted in 2013 and 2014 and resulted in the removal of one hundred and twenty three feral hogs weighing 18, 393 lbs. from the Florida environment
OntoGene in BioCreative II
BACKGROUND: Research scientists and companies working in the domains of biomedicine and genomics are increasingly faced with the problem of efficiently locating, within the vast body of published scientific findings, the critical pieces of information that are needed to direct current and future research investment. RESULTS: In this report we describe approaches taken within the scope of the second BioCreative competition in order to solve two aspects of this problem: detection of novel protein interactions reported in scientific articles, and detection of the experimental method that was used to confirm the interaction. Our approach to the former problem is based on a high-recall protein annotation step, followed by two strict disambiguation steps. The remaining proteins are then combined according to a number of lexico-syntactic filters, which deliver high-precision results while maintaining reasonable recall. The detection of the experimental methods is tackled by a pattern matching approach, which has delivered the best results in the official BioCreative evaluation. CONCLUSION: Although the results of BioCreative clearly show that no tool is sufficiently reliable for fully automated annotations, a few of the proposed approaches (including our own) already perform at a competitive level. This makes them interesting either as standalone tools for preliminary document inspection, or as modules within an environment aimed at supporting the process of curation of biomedical literature
Interaction between vortices in models with two order parameters
The interaction energy and force between widely separated strings is analyzed
in a field theory having applications to superconducting cosmic strings, the
SO(5) model of high-temperature superconductivity, and solitons in nonlinear
optics. The field theory has two order parameters, one of which is broken in
the vacuum (giving rise to strings), the other of which is unbroken in the
vacuum but which could nonetheless be broken in the core of the string. If this
does occur, there is an effect on the energetics of widely separated strings.
This effect is important if the length scale of this second order parameter is
longer than that of the other fields in the problem.Comment: 11 pages, 3 figures. Minor changes in the text. Accepted for
publication in Phys. Rev.
Mediterranean Diet and Breast Density in the Minnesota Breast Cancer Family Study
Mediterranean populations’ lower breast cancer incidence has been attributed to a traditional Mediterranean diet, but few studies have quantified Mediterranean dietary pattern intake in relation to breast cancer. We examined the association of a Mediterranean diet scale (MDS) with mammographic breast density as a surrogate marker for breast cancer risk. Participants completed a dietary questionnaire and provided screening mammograms for breast density assessment using a computer-assisted method. Among 1,286 women, MDS was not clearly associated with percent density in multivariate linear regression analyses. Because of previous work suggesting dietary effects limited to smokers, we conducted stratified analyses and found MDS and percent density to be significantly, inversely associated among current smokers (β = –1.68, P = 0.002) but not among nonsmokers (β = –0.08, P = 0.72; P for interaction = 0.008). Our results confirm a previous suggestion that selected dietary patterns may be protective primarily in the presence of procarcinogenic compounds such as those found in tobacco smoke
The Benefits and the Costs of Using Auditory Warning Messages in Dynamic Decision Making Settings
The failure to notice critical changes in both visual and auditory scenes may have important consequences for performance in complex dynamic environments, especially those related to security such as aviation, surveillance during major events, and command and control of emergency response. Previous work has shown that a significant number of situation changes remain undetected by operators in such environments. In the current study, we examined the impact of using auditory warning messages to support the detection of critical situation changes and to a broader extent the decision making required by the environment. Twenty-two participants performed a radar operator task involving multiple subtasks while detecting critical task-related events that were cued by a specific type of audio message. Results showed that about 22% of the critical changes remained undetected by participants, a percentage similar to that found in previous work using visual cues to support change detection. However, we found that audio messages tended to bias threat evaluation towards perceiving objects as more threatening than they were in reality. Such findings revealed both benefits and costs associated with using audio messages to support change detection in complex dynamic environments
Sensitivity and discovery potential of the proposed nEXO experiment to neutrinoless double beta decay
The next-generation Enriched Xenon Observatory (nEXO) is a proposed
experiment to search for neutrinoless double beta () decay in
Xe with a target half-life sensitivity of approximately years
using kg of isotopically enriched liquid-xenon in a time
projection chamber. This improvement of two orders of magnitude in sensitivity
over current limits is obtained by a significant increase of the Xe
mass, the monolithic and homogeneous configuration of the active medium, and
the multi-parameter measurements of the interactions enabled by the time
projection chamber. The detector concept and anticipated performance are
presented based upon demonstrated realizable background rates.Comment: v2 as publishe
Characterization of an Ionization Readout Tile for nEXO
A new design for the anode of a time projection chamber, consisting of a
charge-detecting "tile", is investigated for use in large scale liquid xenon
detectors. The tile is produced by depositing 60 orthogonal metal
charge-collecting strips, 3~mm wide, on a 10~\si{\cm} 10~\si{\cm}
fused-silica wafer. These charge tiles may be employed by large detectors, such
as the proposed tonne-scale nEXO experiment to search for neutrinoless
double-beta decay. Modular by design, an array of tiles can cover a sizable
area. The width of each strip is small compared to the size of the tile, so a
Frisch grid is not required. A grid-less, tiled anode design is beneficial for
an experiment such as nEXO, where a wire tensioning support structure and
Frisch grid might contribute radioactive backgrounds and would have to be
designed to accommodate cycling to cryogenic temperatures. The segmented anode
also reduces some degeneracies in signal reconstruction that arise in
large-area crossed-wire time projection chambers. A prototype tile was tested
in a cell containing liquid xenon. Very good agreement is achieved between the
measured ionization spectrum of a Bi source and simulations that
include the microphysics of recombination in xenon and a detailed modeling of
the electrostatic field of the detector. An energy resolution =5.5\%
is observed at 570~\si{keV}, comparable to the best intrinsic ionization-only
resolution reported in literature for liquid xenon at 936~V/\si{cm}.Comment: 18 pages, 13 figures, as publishe
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