1,757 research outputs found
Photoelectrocatalytic performances of nanostructured/decorated TiO 2 electrodes: Effect of wavelength and cell configuration
The behaviour of TiO2 based electrodes was investigated during the photoelectrocatalytic water splitting process. TiO2 nanotubes and compact oxide structures were obtained by electrochemical oxidation of Ti foils. A subsequent hydrothermal process carried out at both the nanotubular and compact oxide structures allowed decorating the structure by TiO2 nanoparticles. The synthesized TiO2 samples worked as photoanodes both in a bulk three electrode cell and in a thin gap cell. The results from measurements of the photocurrent and from electrochemical impedance spectroscopy were used to highlight a combined effect of the wavelength of the incident light and the kind of cell configuration, on the global performance of the systems. The results indicate that the decoration process does not result only in a simple increase of the specific surface, but it also determines a different concentration of the bulk and superficial sites in the electrode. The different response of the sites at different wavelengths, along with the accessibility of the electrolyte to the porous structure are evocated to justify the experimental behaviour observed
Early Death in Two Patients with Acute Promyelocytic Leukemia Presenting the bcr3 Isoform, FLT3-ITD Mutation, and Elevated WT1 Level
Despite major advances in the treatment of acute promyelocytic leukemia (APL), the problem of early death (ED) remains unsolved. Alongside the currently known clinical and hematological risk factors, prognostic significance has been attributed to internal tandem duplication mutations of the fms-like tyrosine kinase-3 (FLT3-ITD), hypogranular variant morphology, and the bcr-3 isoform of PML-RARα. We describe premature death of two patients with the hypogranular variant of APL who presented remarkably high expression levels of Wilms' tumor gene (WT1). Our results point to WT1 as an important prognostic factor of ED that needs to be promptly evaluated in all newly diagnosed cases of APL
Deciphering the local Interstellar spectra of primary cosmic ray species with HelMod
Local interstellar spectra (LIS) of primary cosmic ray (CR) nuclei, such as
helium, oxygen, and mostly primary carbon are derived for the rigidity range
from 10 MV to ~200 TV using the most recent experimental results combined with
the state-of-the-art models for CR propagation in the Galaxy and in the
heliosphere. Two propagation packages, GALPROP and HelMod, are combined into a
single framework that is used to reproduce direct measurements of CR species at
different modulation levels, and at both polarities of the solar magnetic
field. The developed iterative maximum-likelihood method uses GALPROP-predicted
LIS as input to HelMod, which provides the modulated spectra for specific time
periods of the selected experiments for model-data comparison. The interstellar
and heliospheric propagation parameters derived in this study are consistent
with our prior analyses using the same methodology for propagation of CR
protons, helium, antiprotons, and electrons. The resulting LIS accommodate a
variety of measurements made in the local interstellar space (Voyager 1) and
deep inside the heliosphere at low (ACE/CRIS, HEAO-3) and high energies
(PAMELA, AMS-02).Comment: 13 pages, 13 figures, 6 tables, ApJ in press. arXiv admin note: text
overlap with arXiv:1704.0633
HelMod in the works: from direct observations to the local interstellar spectrum of cosmic-ray electrons
The local interstellar spectrum (LIS) of cosmic-ray (CR) electrons for the
energy range 1 MeV to 1 TeV is derived using the most recent experimental
results combined with the state-of-the-art models for CR propagation in the
Galaxy and in the heliosphere. Two propagation packages, GALPROP and HelMod,
are combined to provide a single framework that is run to reproduce direct
measurements of CR species at different modulation levels, and at both
polarities of the solar magnetic field. An iterative maximum-likelihood method
is developed that uses GALPROP-predicted LIS as input to HelMod, which provides
the modulated spectra for specific time periods of the selected experiments for
model-data comparison. The optimized HelMod parameters are then used to adjust
GALPROP parameters to predict a refined LIS with the procedure repeated subject
to a convergence criterion. The parameter optimization uses an extensive data
set of proton spectra from 1997-2015. The proposed CR electron LIS accommodates
both the low-energy interstellar spectra measured by Voyager 1 as well as the
high-energy observations by PAMELA and AMS-02 that are made deep in the
heliosphere; it also accounts for Ulysses counting rate features measured out
of the ecliptic plane. The interstellar and heliospheric propagation parameters
derived in this study agree well with our earlier results for CR protons,
helium nuclei, and anti-protons propagation and LIS obtained in the same
framework.Comment: 11 pages, 14 figures, 4 tables; ApJ, in pres
The Carers’ Needs Assessment for Dementia (CNA-D): a validation study in the Italian population
Simulations of the polarized radio sky and predictions on the confusion limit in polarization for future radio surveys
Numerical simulations offer the unique possibility to forecast the results of
surveys and targeted observations that will be performed with next generation
instruments like the Square Kilometre Array. In this paper, we investigate for
the first time how future radio surveys in polarization will be affected by
confusion noise. To do this, we produce 1.4 GHz simulated full-Stokes images of
the extra-galactic sky by modelling various discrete radio sources populations.
The results of our modelling are compared to data in the literature to check
the reliability of our procedure. We also estimate the number of polarized
sources detectable by future surveys. Finally, from the simulated images we
evaluate the confusion limits in I, Q, and U Stokes parameters, giving
analytical formulas of their behaviour as a function of the angular resolution.Comment: 9 pages, 8 figure
Simulations of the polarized radio sky and predictions on the confusion limit in polarization for future radio surveys
Numerical simulations offer the unique possibility to forecast the results of surveys and targeted observations that will be performed with next generation instruments like the Square Kilometre Array. In this paper, we investigate for the first time how future radio surveys in polarization will be affected by confusion noise. To do this, we produce 1.4 GHz simulated full-Stokes images of the extra-galactic sky by modelling various discrete radio sources populations. The results of our modelling are compared to data in the literature to check the reliability of our procedure. We also estimate the number of polarized sources detectable by future surveys. Finally, from the simulated images we evaluate the confusion limits in I, Q, and U Stokes parameters, giving analytical formulas of their behaviour as a function of the angular resolution
Cocirculation of Hajj and non-Hajj strains among serogroup W meningococci in Italy, 2000 to 2016
In Italy, B and C are the predominant serogroups among meningococci causing invasive diseases. Nevertheless, in the period from 2013 to 2016, an increase in serogroup W Neisseria meningitidis (MenW) was observed. This study intends to define the main characteristics of 63 MenW isolates responsible of invasive meningococcal disease (IMD) in Italy from 2000 to 2016. We performed whole genome sequencing on bacterial isolates or single gene sequencing on culturenegative samples to evaluate molecular heterogeneity. Our main finding was the cocirculation of the Hajj and the South American sublineages belonging to MenW/ clonal complex (cc)11, which gradually surpassed the MenW/cc22 in Italy. All MenW/cc11 isolates were fully susceptible to cefotaxime, ceftriaxone, ciprofloxacin, penicillin G and rifampicin. We identified the fulllength NadA protein variant 2/3, present in all the MenW/cc11. We also identified the fHbp variant 1, which we found exclusively in the MenW/cc11/Hajj sublineage. Concern about the epidemic potential of MenW/cc11 has increased worldwide since the year 2000. Continued surveillance, supported by genomic characterisation, allows high-resolution tracking of pathogen dissemination and the detection of epidemicassociated strains
- …