Novel role of cPLA2α in membrane and actin dynamics

Actin-directed processes such as membrane ruffling and cell migration are regulated by specific signal transduction pathways that become activated by growth factor receptors. The same signaling pathways that lead to modifications in actin dynamics also activate cPLA2α. Moreover, arachidonic acid, the product of cPLA2α activity, is involved in regulation of actin dynamics. Therefore, it was investigated whether cPLA2α plays a role in actin dynamics, more specifically during growth factor-induced membrane ruffling and cell migration. Upon stimulation of ruffling and cell migration by growth factors, endogenous cPLA2α and its active phosphorylated form were shown to relocate at protrusions of the cell membrane involved in actin and membrane dynamics. Inhibition of cPLA2α activity with specific inhibitors blocked growth factor-induced membrane and actin dynamics, suggesting an important role for cPLA2α in these processes

Stretching the spines of gymnasts: a review

Gymnastics is noted for involving highly specialized strength, power, agility and flexibility. Flexibility is perhaps the single greatest discriminator of gymnastics from other sports. The extreme ranges of motion achieved by gymnasts require long periods of training, often occupying more than a decade. Gymnasts also start training at an early age (particularly female gymnasts), and the effect of gymnastics training on these young athletes is poorly understood. One of the concerns of many gymnastics professionals is the training of the spine in hyperextension-the ubiquitous 'arch' seen in many gymnastics positions and movements. Training in spine hyperextension usually begins in early childhood through performance of a skill known as a back-bend. Does practising a back-bend and other hyperextension exercises harm young gymnasts? Current information on spine stretching among gymnasts indicates that, within reason, spine stretching does not appear to be an unusual threat to gymnasts' health. However, the paucity of information demands that further study be undertaken

Do Code of Points in men artistic gymnastics and women artistic gymnastics favor asymmetric elements?

Abstract The purpose of research was to determine whether Code of Point (COP) in Men Artistic Gymnastics (MAG) and Women Artistic Gymnastics (WAG) favor asymmetric elements in order to build gymnast’s competition exercise. All elements which are described in MAG (N = 993) and WAG (N = 713) COP were included and defined if they are symmetric at start position, during movement and at final position. Element is symmetric by arms and trunk with legs activity when all left and right body side performs simultaneously same activity. Results show in MAG COP as a whole is significantly more asymmetric elements with asymmetric trunk and legs activity. In WAG COP as a whole is significantly more asymmetric elements with asymmetric activity of arms, trunk and legs. Hypothetical most difficulty exercises on each apparatus revealed that in general for all around gymnast proportion between asymmetric and symmetric elements is close to 70% to 30%, what suggests that difficulty relates to increased asymmetry. COP in MAG and WAG enforces asymmetric movements for achieving high results, however, coaches’ task is to be aware of COP influence on gymnasts’ health and minimize asymmetries in load and to work on symmetric conditioning