25 research outputs found

    Threads of memory: Reviving the ornament of a dead child at the Neolithic village of Ba'ja (Jordan)

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    In 2018, a well-constructed cist-type grave was discovered at Ba'ja, a Neolithic village (7,400-6,800 BCE) in Southern Jordan. Underneath multiple grave layers, an 8-year-old child was buried in a fetal position. Over 2,500 beads were found on the chest and neck, along with a double perforated stone pendant and a delicately engraved mother-of-pearl ring discovered among the concentration of beads. The first was found behind the neck, and the second on the chest. The meticulous documentation of the bead distribution indicated that the assemblage was a composite ornament that had gradually collapsed, partly due to the burying position. Our aim was to challenge time degradation and to reimagine the initial composition in order to best explore the significance of this symbolic category of material culture, not as mere group of beads, but as an ornamental creation with further aesthetic, artisanal and socioeconomic implications. The reconstruction results exceeded our expectations as it revealed an imposing multi-row necklace of complex structure and attractive design. Through multiple lines of evidence, we suggest that the necklace was created at Ba'ja, although significant parts of beads were made from exotic shells and stones, including fossil amber, an unprecedented material never attested before for this period. The retrieval of such an ornament from life and its attribution to a young dead child highlights the significant social status of this individual. Beyond the symbolic functions related to identity, the necklace is believed to have played a key role in performing the inhumation rituals, understood as a public event gathering families, relatives, and people from other villages. In this sense, the necklace is not seen as belonging completely to the realm of death but rather to the world of the living, materializing a collective memory and shared moments of emotions and social cohesion.ArchaeologyHub.CSIC 2022 Internal Research Grant (HA) https://archaeologyhub.csic.es/ - H2020 Marie Sklodowska-Curie Actions, grant number 846097 (HA) https://cordis.europa.eu/project/id/846097 - German Research Foundation (BO 1599/14-1; BO 1599/16-1) (MB, HGG) https://www.dfg.de/en/ - Franz-and Eva Rutzen Stiftung Foundation (MB) https://www.deutsches-stiftungszentrum.de/stiftungen/franz-und-eva-rutzen-stiftung - Junta de Andalucía (Consejería de Economía, Conocimiento, Empresas y Universidad), under contract P20_01080 (CPO) https://www.juntadeandalucia.es/organismos/universidadinvestigacioneinnovacion.htm

    Carlo Cristini: un ricordo a più voci

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    Ricordo di Carlo Cristini quale ricercatore nell'ambito della psicologia dell'invecchiament

    Analysis of Dentin/Enamel Remineralization by a CPP-ACP Paste: AFM and SEM Study.

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    The aim of the present in vitro study was the evaluation of a CPP-ACP paste on preventing dentin/enamel erosion produced by a soft drink; Atomic Force Microscopy and Scanning Electron Microscopy were used. Eighty extracted human incisors free of caries were selected and divided into four groups (each divided in two subgroups); group 1a: intact dentin; group 1b: dentin + soft drink; group 2a: intact dentin + CCP-ACP paste; group 2b: dentin + soft drink + CCP-ACP paste; group 3a: intact enamel; group 3b: enamel + soft drink; group 4a: intact enamel + CCP-ACP paste; group 4b: enamel + soft drink + CCP-ACP paste. The CPP-ACP paste was applied for 3 min at 0, 8, 24, and 36 h. The surface of each dentin/enamel specimen was imaged by AFM (R(rms) values were registered) and SEM. A statistical significant difference was recorded between groups 1b (dentin + soft drink) and 2b (dentin + soft drink + CCP-ACP paste) and between groups 3b (enamel + soft drink) and 4b (enamel + soft drink + CCP-ACP paste), suggesting that treatment of the specimens with the CPP-ACP paste had a protective effect on enamel demineralization, which was more evident for enamel specimens. Under the limitations of the present in vitro study, it can be concluded that the application of a CPP-ACP paste is effective on preventing dentin/enamel erosion produced by a soft drink

    Changes in the zonation of lactate dehydrogenase activity in lobules of rat liver after experimentally induced colon carcinoma metastases

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    Visualization of lactate dehydrogenase (LDH) activity with Neotetrazolium as final electron acceptor under anaerobic conditions and an incubation medium containing polyvinyl alcohol showed that under normal physiological conditions a zonal distribution of LDH activity is present in the liver lobule of male rats. Periportal hepatocytes contain more LDH activity than periventral hepatocytes. This difference is due to the role of LDH both in gluconeogenesis (periportal cells) and glycolysis (pericentral cells). In livers containing metastases from colon carcinoma, areas of the parenchyma which are not affected by tumour growth maintain such zonation in the lobule, whereas areas close to metastatic foci show increased activity which is distributed uniformly over the lobule. This change may be explained by a Cori's cycle-like relationship between malignancy cells and the surrounding hepatocytes due to glucose consumption and lactate production by the tumour cells. Within the metastatic foci, a zonation of LDH activied was also observed. Malignant cells close to the edge of the tumours contained the lowest activity, whereas activity increased inwards. Cancer cells directly surrounding necrotiic areas showed the highest activity. Such patterns are in line with increasing anaerobic glycolysis towards the inner metastatic regions. Anaerobic glycolysis supplies limited amounts of ATP with concomitant lactate production but also large amounts of metabolites for RNA, DNA, lipid and complex carbohydrate synthesis. Lactate that is produced by the metastases induces adaptive changes in surrounding hepatocytes to convert this excess of lactate effectivel

    The role of different toothpastes on preventing dentin erosion: An SEM and AFM study®

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    The aim of the present in vitro study was the evaluation of new formulation toothpastes on preventing dentin erosion produced by a soft drink (Coca Cola®), using atomic force microscopy (AFM) and scanning electron microscopy (SEM). Fifty dentin specimens were divided in treatment and control halves and were than assigned to 5 groups of 10 specimens each: group 1a: intact dentin, group 1b: dentin + soft drink, group 2a: intact dentin + Biorepair Plus-Sensitive Teeth®, group 2b: dentin + soft drink + Biorepair Plus-Sensitive Teeth®, group 3a: intact dentin + Biorepair Plus-Total Protection®, group 3b: dentin + soft drink + Biorepair Plus-Total Protection®, group 4a: intact dentin + Sensodyne Repair & Protect®, group 4b: dentin + soft drink + Sensodyne Repair & Protect®, group 5a: intact dentin + Colgate Sensitive Pro Relief®, group 5b: dentin + soft drink + Colgate Sensitive Pro Relief®. The surface of each specimen was imaged by AFM and SEM. Comparing specimens of group a and b (no demineralization and demineralization), a statistically significant difference (p < 0.01) in Rrms values was registered. Comparing b groups, all the analyzed toothpastes tended to remineralize the dentine surface in different extent. Biorepair Plus-Total Protection® and Sensodyne Repair & Protect® provided higher protective effect against dentin demineralizatio

    The effect of dietary guar on serum cholesterol, intestinal transit and fecal output in man

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    n six healthy subjects serum cholesterol was unchanged during a 2-wk period of controlled diet (2750 kcal) followed by a 2-wk period of free diet but showed a 16% decrease (p less than 0.05) during a further 2-wk period of controlled diet to which guar (5.7 g bid) was added. Stool weight, frequency and whole gut transit time did not differ in the diet periods with and without guar. Of guar ingested 82-95% was metabolized in the gut. Mouth to cecum transit of a meal measured by the hydrogen breath test in the same subjects was unaffected by the addition of 5.7 g of guar

    Upgrade of the x-ray imaging set-up at CCR &quot;La Venaria Reale&quot;: The case study of an Egyptian wooden statuette

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    X-ray based imaging techniques (digital radiography and computed tomography) are widely used in the field of Cultural Heritage and beyond, above all thanks to their non-invasiveness. The high penetrating power of X-rays allows us to investigate the internal structure of the analysed objects, thus obtaining valuable information related to the history of artistic and archaeological finds. In particular, CT provides data that are more significant when objects with a not negligible volume are studied. Even the use of advanced instruments can help having better final data from which getting more information. In this paper, we will show the case study of an Ancient Egyptian wooden statuette representing a “bearer”, for which an upgraded version of the X-ray imagingapparatus located in the Centro Conservazione e Restauro “La Venaria Reale” (CCR) was used for the first time. Thanks to this, much information on the technique of execution was obtained, especially from the tomographic analysis
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