Nitroxide malonate methanofullerene as biomimetic model of interaction of nitroxide species with antioxidants

AbstractBis-nitroxide malonate methanofullerene (NO)2-MF was studied as a biomimetic model of reduction–oxidation activity with natural compounds—cytochrome c (cyt c), dihydroquercetin (DHQ), ascorbic acid (AA) and synthetic drug—1-(β-oxyethyl)-4,6-dimethyl-1,2-dihydro-2-oxopyrimidine (xymedon®).(NO)2-MF may be used as the component of Langmuir monolayers on an aqueous subphase and as the adsorbate on silica gel. The activity of (NO)2-MF in the reaction with cyt c was compared with the effect of nitroxide species such as gaseous nitric oxide, 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO) by using UV–vis and EPR-spectra. It has been shown, that iron(III) in cyt c3+ under action (NO)2-MF was reduced up to iron(II), similar effect was observed under the influence of gaseous NO in aqueous solution, but reduction of iron(III) in heme cyt c was reversible in the presence of TEMPO. Therefore, the state of Fe-heme in cyt c can be used as the indicator of the interaction of cyt c with nitroxide species in vitro.The interaction of cyt c, DHQ, xymedon® with (NO)2-MF monolayers was confirmed by the increasing of limiting area А0 from 0.88nm2 up to 1.70nm2 of (NO)2-MF on the aqueous subphase, by the paramagnetism and UV–vis spectral data changes. These results can be explained by appearance of oxoammonium ion (NO+)2-MF adlayers and monolayers.The antioxidant and regenerating effects were shown when treating wounds by xymedon® in the presence of additives (0.001%) of (NO)2-MF in the experiments on the rats

Gain of transportation revenue by optimization of quota allocation for in-between stations

An algorithm for calculation of optimal train ticket selling share for a departure station and in-between stations is proposed to obtain the ceiling total income. Available demand statistics for relevant stations are taken into account. The solution of the problem is reduced to applying of simplex-method to dual linear programming procedure with special objective function

New and little known species of spider wasps (Hymenoptera: Pompilidae) from the Russian Far East

Kochetkov, D.N., Loktionov, V.M. (2019): New and little known species of spider wasps (Hymenoptera: Pompilidae) from the Russian Far East. Far Eastern Entomologist 382: 1-9, DOI: 10.25221/fee.382.1, URL: http://dx.doi.org/10.25221/fee.382.

Figs 3–12 in New and little known species of spider wasps (Hymenoptera: Pompilidae) from the Russian Far East

Figs 3–12. Stigmatodipogon khinganicus Kochetkov et Loktionov, sp. n., holotype,Published as part of Kochetkov, D.N. & Loktionov, V.M., 2019, New and little known species of spider wasps (Hymenoptera: Pompilidae) from the Russian Far East, pp. 1-9 in Far Eastern Entomologist 382 on page 4, DOI: 10.25221/fee.382.1, http://zenodo.org/record/716491

Investigation of the structure of coatings of self fluxing alloys fused by laser energy

Translated from Russian (Stal' 1987 (1) p. 88-91)SIGLEAvailable from British Library Document Supply Centre- DSC:5828.4(M--37301)T / BLDSC - British Library Document Supply CentreGBUnited Kingdo