245 research outputs found
Anderson localization of a Tonks-Girardeau gas in potentials with controlled disorder
We theoretically demonstrate features of Anderson localization in the
Tonks-Girardeau gas confined in one-dimensional (1D) potentials with controlled
disorder. That is, we investigate the evolution of the single particle density
and correlations of a Tonks-Girardeau wave packet in such disordered
potentials. The wave packet is initially trapped, the trap is suddenly turned
off, and after some time the system evolves into a localized steady state due
to Anderson localization. The density tails of the steady state decay
exponentially, while the coherence in these tails increases. The latter
phenomenon corresponds to the same effect found in incoherent optical solitons
Significant contribution to total mass from very small glaciers
A single large glacier can contain tens of millions of times the mass of a small glacier. Nevertheless, very small glaciers (with area &le;1 km<sup>2</sup>) are so numerous that their contribution to the world's total ice volume is significant and may be a notable source of error if excluded. With current glacier inventories, total global volume errors on the order of 10% are possible. However, to reduce errors to below 1% requires the inclusion of glaciers that are smaller than those recorded in most inventories. At the global scale, 1% accuracy requires a list of all glaciers and ice caps (GIC, exclusive of the ice sheets) larger than 1 km<sup>2</sup>, and for regional estimates requires a complete list of all glaciers down to the smallest possible size. For this reason, sea-level rise estimates and other total mass and total volume analyses should not omit the world's smallest glaciers. In particular, upscaling GIC inventories has been common practice in sea level estimates, but downscaling may also be necessary to include the smallest glaciers
Inhibition of Cholinesterases by the Oximes P2AM and Toxogonin
The reversible inhibition of electric eel acetylcholinesterase
(EC 3.1.1.7) by P2AM (2-(hydroxyimino)methyl-1-methyl-pyridinium
chloride) and Toxogonin (1,1\u27-[oxybis(methylene)] bis(4-(hydroxyimino)
methyl-pyridinium) dichloride) was studied using ac.etylthiocholine
as substrate. Two techniques were applied for
measuring acetylthiocholine hydrolysis, the conventional spectrophotometric
and the stopped-flow (at 25 °c in 100 mM phosphate
buffer pH = 7.4).
The correlation between the degree of inhibition, and acetylthiocholine
and oxime concentrations fits a theoretical model which
postulates that the substrate and the inhibitor bind to two sites on
the enzyme: the catalytic site and an allosteric, substrate-inhibition,
site. The calculated dissociation constants for the two sites
are: 0.13 and 0.76 mM for P2AM, and 0.16 and 2.0 mM for Toxogonin.
The suggested model is an alternative to the hypothesis that
two types of binding occur within the catalytic site.
Horse serum cholinesterase and bovine erythrocyte acetylcholinesterase
are also inhibited by P2AM and Toxogonin to about
the same degree as the electric eel enzyme.
Acetylthiocholine reacts with P2AM and Toxogonin; assuming
that the reaction is bimolecular the corresponding rate constants
are 13.4 and 22.4 M-1 min-
Navarivanje vijenaca monoblok točka (MBT) čelika R7T za željeznička vozila
The steel R7T monoblock wheel material properties are defined by the International Declaration UIC 812-3. Taking into consideration the resurfacing of the rim, the analyzed conditions for the resurfacing, as well as the analysis of the chemical compounds, mechanical characteristics (material hardness, pulling strength, and tenacity), ultrasound and metallographic testing, which proved that the resurfaced rim area has the required characteristics, according to the Declaration UIC 812-3.Svojstva materijala monobloka točkova čelika R7T su određeni po međunarodnoj objavi UIC 812-3. Na temelju navarivanja vijencaovih točkova, istraživanih uvjeta za navarivanje, te ispitivanjem kemijskog sastava, mehničkih svojstava (tvrdoće, vlačne čvrstoće, žilavosti), ultrazvučnim i metalograpskim ispitivanjima, dokazano je da navareni sloj vijenca ima osobine sukladne traženim po objavi UIC 812-3
Modelling ice dynamic contributions to sea level rise from the Antarctic Peninsula
The future ice dynamical contribution to sea-level rise (SLR) from 210 ice shelf nourishing drainage basins of the Antarctic Peninsula Ice Sheet (APIS) is simulated, using the British Antarctic Survey Antarctic Peninsula Ice Sheet Model. Simulations of the grounded ice sheet include response to ice-shelf collapse, estimated by tracking thermal ice shelf viability limits in 14 IPCC Global Climate Model ensemble temperature projections. Grounding line retreat in response to ice shelf collapse is parameterized with a new multivariate linear regression model utilizing a range of glaciological and geometric predictor variables. Multi-model means project SLR up to 9.4 mm sea-level equivalent (SLE) by 2200, and up to 19 mm SLE by 2300. Rates of SLR from individual drainage basins throughout the peninsula are similar to 2100, yet diverge between 2100 and 2300 due to individual basin characteristics. Major contributors to SLR are the outlet glaciers feeding southern George VI Ice Shelf, accounting for >75% of total SLR in some model runs. Ice sheet thinning induced by ice-shelf removal is large (up to ∼500 m), especially in Palmer Land in the Southern Antarctic Peninsula, and may propagate as far as 135 km inland. These results emphasize the importance of the ice dynamical contribution to future sea level of the APIS on decadal to centennial timescales
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Imidazole aldoximes effective in assisting butyrylcholinesterase catalysis of organophosphate detoxification.
Intoxication by organophosphate (OP) nerve agents and pesticides should be addressed by efficient, quickly deployable countermeasures such as antidotes reactivating acetylcholinesterase or scavenging the parent OP. We present here synthesis and initial in vitro characterization of 14 imidazole aldoximes and their structural refinement into three efficient reactivators of human butyrylcholinesterase (hBChE) inhibited covalently by nerve agent OPs, sarin, cyclosarin, VX, and the OP pesticide metabolite, paraoxon. Rapid reactivation of OP-hBChE conjugates by uncharged and nonprotonated tertiary imidazole aldoximes allows the design of a new OP countermeasure by conversion of hBChE from a stoichiometric to catalytic OP bioscavenger with the prospect of oral bioavailability and central nervous system penetration. The enhanced in vitro reactivation efficacy determined for tertiary imidazole aldoximes compared to that of their quaternary N-methyl imidazolium analogues is attributed to ion pairing of the cationic imidazolium with Asp 70, altering a reactive alignment of the aldoxime with the phosphorus in the OP-hBChE conjugate
Thermoelectrical manipulation of nanomagnets
We investigate the interplay between the thermodynamic properties and
spin-dependent transport in a mesoscopic device based on a magnetic multilayer
(F/f/F), in which two strongly ferromagnetic layers (F) are exchange-coupled
through a weakly ferromagnetic spacer (f) with the Curie temperature in the
vicinity of room temperature. We show theoretically that the Joule heating
produced by the spin-dependent current allows a spin-thermo-electronic control
of the ferromagnetic-to-paramagnetic (f/N) transition in the spacer and,
thereby, of the relative orientation of the outer F-layers in the device
(spin-thermo-electric manipulation of nanomagnets). Supporting experimental
evidence of such thermally controlled switching from parallel to antiparallel
magnetization orientations in F/f(N)/F sandwiches is presented. Furthermore, we
show theoretically that local Joule heating due to a high concentration of
current in a magnetic point contact or a nanopillar can be used to reversibly
drive the weakly ferromagnetic spacer through its Curie point and thereby
exchange couple and decouple the two strongly ferromagnetic F-layers. For the
devices designed to have an antiparallel ground state above the Curie point of
the spacer, the associated spin-thermionic parallel-to-antiparallel switching
causes magneto-resistance oscillations whose frequency can be controlled by
proper biasing from essentially DC to GHz. We discuss in detail an experimental
realization of a device that can operate as a thermo-magneto-resistive switch
or oscillator.Comment: This paper, published in J. Appl. Phys. 107, 123706 (2010), is an
expanded version of arXiv:0710.5477 (8 pages, 12 figures, two additional
authors and experimental section added
Spin-thermo-electronic oscillator based on inverse giant magnetoresistance
A spin-thermo-electronic valve with the free layer of exchange-spring type
and inverse magnetoresistance is investigated. The structure has S-shaped
current-voltage characteristics and can exhibit spontaneous oscillations when
integrated with a conventional capacitor within a resonator circuit. The
frequency of the oscillations can be controlled from essentially dc to the GHz
range by the circuit capacitance.Comment: 7 pages, 9 figure
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