INCREASE IN EFFICIENCY OF THE CYCLIC DRIVING OF WELLS IN SOIL

Processing methods of a cyclic driving of wells with a diameter over 300 mm by methods of vibro-impact pushing and combined with partial consolidation and excavation of soil on the basis of use of pneumo-percussive mashines (pneumatic bore-hole driver) are given in work. The results of researches received with use of the ground intake devices physical models have allowed to establish characteristics of change of force of resistance to the return transportation of the equipment with the taken soil core in process of his removal from a face. Analytical expressions for engineering calculation of the winch tractive force are received. Technical characteristics of the created number of the winches of scraper type working at the uniform energy carrier with shock cars – compressed air are given.The schematic diagram winch with hybrid pneumatic drive, the having variable traction and high-speed characteristic is offered at a limited expense of the energy carrier which realization of a design at vibroshock breakdown and a combined method allows to reduce time of a production cycle of formation of wells and to increase productivity of driving works. A schematic diagram of a winch with a hybrid pneumatic drive is proposed, which has variable traction and speed characteristics with a limited energy carrier consumption, the implementation of the design which in vibro-impact pushing and combined method allows to reduce time of process of formation of wells and improve the performance of the tunneling works

Integration of evidence across human and model organism studies: A meeting report

The National Institute on Drug Abuse and Joint Institute for Biological Sciences at the Oak Ridge National Laboratory hosted a meeting attended by a diverse group of scientists with expertise in substance use disorders (SUDs), computational biology, and FAIR (Findability, Accessibility, Interoperability, and Reusability) data sharing. The meeting\u27s objective was to discuss and evaluate better strategies to integrate genetic, epigenetic, and \u27omics data across human and model organisms to achieve deeper mechanistic insight into SUDs. Specific topics were to (a) evaluate the current state of substance use genetics and genomics research and fundamental gaps, (b) identify opportunities and challenges of integration and sharing across species and data types, (c) identify current tools and resources for integration of genetic, epigenetic, and phenotypic data, (d) discuss steps and impediment related to data integration, and (e) outline future steps to support more effective collaboration-particularly between animal model research communities and human genetics and clinical research teams. This review summarizes key facets of this catalytic discussion with a focus on new opportunities and gaps in resources and knowledge on SUDs