Horndeski Genesis: strong coupling and absence thereof

We consider Genesis in the Horndeski theory as an alternative to or completion of the inflationary scenario. One of the options free of instabilities at all cosmological epochs is the one in which the early Genesis is naively plagued with strong coupling. We address this issue to see whether classical field theory description of the background evolution at this early stage is consistent, nevertheless. We argue that, indeed, despite the fact that the effective Plank mass tends to zero at early time asymptotics, the classical analysis is legitimate in a certain range of Lagrangian parameters.Comment: 10 pages, 1 figur

Laparoscopic Roux-en-Y reconstruction in a patient with afferent loop syndrome and peptic ulcers of gastroenteroanastomosis - A first experience

This paper is devoted to the description of a currently rare clinical observation of the surgical treatment of a patient with postgastroresection syndrome (afferent loop syndrome and peptic ulcers of gastroenteroanastomosis) - resection of the stomach stump with laparoscopic Roux-en-Y reconstructio

Development of the Republic of Sakha (Yakutia)'s Shadow Economy Assessment Methodology

The purpose of the article is to study the shadow economy assessment methodology. This article presents a comprehensive study of the parameters of a shadow economy, considers its essence, and defines its terminology. This study outlines the historical approach to the development of the shadow economy, both in Russia and worldwide, and gives a brief analysis of the economy of the Republic of Sakha. The authors examined the specifics of the statistical methods applied in assessing various structural elements of a shadow economy and measured and assessed the shadow economy in this region. The research conducted enabled the authors to formulate the main measures required to reduce the shadow economy. The scientific novelty is justified by the research results, which included studying and summarizing a wide range of published and unpublished materials, the examination of the initial and transitional periods of the shadow economy development in Yakutia. The article reveals the main causes and conditions that lead to the formation of the shadow economy in various sectors of the Yakutia economy. The solutions and suggestions proposed in the article are aimed at reducing the shadow economy parameters. The scientific research results are of theoretical and applied importance for public administration and authorities to improve the effectiveness of the fight against the shadow economy manifestations

Формирование устойчивого развития агропромышленного комплекса региона Припятского Полесья через создание прочной кормовой базы на загрязненных радионуклидами землях

Агропромышленный комплекс нашей страны по данным 2020 года вносит вклад в размере 6 % от общего ВВП. Сельскохозяйственные организации производят около 80 % всех потребляемых продуктов питания. Устойчивое функционирование агропромышленного комплекса невозможно без четкого экономического обоснования и планирования затрат. Разработка оптимального плана производственной программы сельскохозяйственного предприятия ориентирует на научно-обоснованный подход в планировании, обеспечивает рациональное сочетание отраслей и повышение эффективности производств

Natural study of marginal array rock`s stress state

Safety working out water-soluble ore fields in many ways depends on the stability of chamber development system`s elements. To monitor the interchamber pillars` status a method of experimental and theoretical evaluation of the geomechanical processes taking place in the array was developed, the essence of which lies in the meaningful results interpretation of mechanical characteristics and the stress state experimental studies of load-carrying structures by mathematical modeling methods. The article describes the method of estimating the marginal rock array`s stress state. The tension control was made using an acoustic memory effect. The measurements were performed in the wells with the help of a Goodman hydraulic jack. Its feature is the ability to create a load on the borehole array in the same plane, that allows to evaluate the stress magnitude in various directions. During the loading of the measuring borehole walls there is a discontinuous increase in the activity of acoustic emission. The pressure, which is logged in the hydraulic system, was taken at the level of the natural stresses acting in the marginal array. As a result of complex laboratory and field studies methodological features of stress analysis were identified using memory effects in salt rocks of the Verkhnekamskoye potash salt deposit. The experimental data analysis showed that in the “fresh” interchamber pillars a bearing pressure maximum is located near the contour of exposure and in 1.8-2.0 times higher than the load of of the overlying rocks` weight (gH). In the central part of the pillar the vertical stress level is 1.25-1.4 gH. With the increase in pillars` service life the marginal array`s stresses magnitude declines to the stress level of the overlying rocks weight. The horizontal stress increases with moving from the pillar contour and are approximately 60-70% of the vertical. These instrumental measurements results are a source data for assessing the long-term sustainability of interchamber pillars in sylvinite layers mining

Interaction of Educational Organizations as a Factor in the Formation of Practical Experience of Students

В статье рассматриваются вопросы формирования практического опыта обучающихся через использование ресурсов нескольких образовательных организаций. Приведен пример взаимодействия организаций среднего профессионального образования.The article deals with the formation of practical experience of students through the use of resources of several educational organizations. An example of interaction of organizations of secondary vocational education is given

Влияние тирозил-D-аланил-глицил-фенилаланил-лейцил-аргинина диацетата (Даларгин) на окислительный стресс у пациентов с тяжелой сочетанной травмой: проспективное клиническое исследование

АКТУАЛЬНОСТЬ: Тяжелая сочетанная травма (ТСТ) остается ведущей причиной смертности и инвалидизации трудоспособного населения. При воздействии повреждающего фактора запускается целый каскад патологических процессов, приводящих к развитию полиорганной недостаточности. ЦЕЛЬ ИССЛЕДОВАНИЯ: Изучить влияние тирозил-D-аланил-глицил-фенилаланил-лейцил-аргинина диацетата (Даларгина) на динамику маркеров окислительного стресса у пациентов с ТСТ и развитие органной дисфункции. МАТЕРИАЛЫ И МЕТОДЫ: В исследование включено 104 пациента с ТСТ. В группе Даларгина 38 пациентов, в группе контроля 66 пациентов. Пациенты из основной группы получали Даларгин в виде постоянной инфузии через шприцевой дозатор в дозе 10 мкг/кг/ч в первые 12 ч от момента поступления в стационар и 5 мкг/кг/ч до 72 ч от момента поступления. Пациенты группы контроля получали стандартное лечение. Показатели окислительного стресса оценивались на момент поступления (0-е сутки), далее 1, 3, 5, 7, 10 и 14-е сутки от начала терапии. РЕЗУЛЬТАТЫ: В основной группе отмечалось значимое снижение маркеров окислительного стресса, таких как малоновый диальдегид, с 1-х суток лечения (р  0,05), однако длительность госпитализации среди выживших пациентов была меньше в группе Даларгина (р < 0,05). Развитие органной дисфункции (острый респираторный дистресс-синдром, острое повреждение почек) встречались меньше в группе Даларгина (р < 0,05), но инфекционные осложнения (пневмония, менингит, нагноение ран) были сопоставимы. ВЫВОДЫ: Даларгин приводит к снижению маркеров окислительного стресса и нормализации показателей эндотелиальной функции, что способствует снижению частоты развития органной дисфункции

INVESTIGATION OF SORPTION CHARACTERISTICS OF POLYMERIC MINERAL-FILLED COMPOSITES FOR MEDICINE

The polymer compositions on the base of acrylic derivatives and bentonite particles modified by silver ions with various share and dispersion are received and studied by radical polymerization in the water. Partially neutralized acrylic acid, acrylamide and methylene-bis-acrilamide and particles of bentonite with fraction 0 - 0,05 mass.% are chosen as initial substances. The influence of bentonite concentration on absorbing characteristics of polymer materials in the distilled water is shown. It is demonstrated that the increase of bentonite fraction up to 5 mass.% leads to the rise of degree of equilibrium swelling by 1,5 – 2 times in comparison with an unfilled polymer matrix. The acrylic nanocompositions with a mass fraction of bentonite equal to 0,01 mass.% possess the greatest kinetic characteristics. Kinetic dependences of new composite materials swelling in physiological solution from a filler dispersion part are investigated. It is shown that in high dispersion (with particle size less than 0,25 mm) a part of mineral–containing filler equal to 1 mass.% leads to significant increase in values of equilibrium swelling degree in comparison with an unfilled sample (by 1,5 times). The effect of polyelectrolyte suppression of polymer composition swelling in physiological solution is studied. It results in values reduction of equilibrium swelling degree in comparison with these values in the distilled water. Application prospects for the received compositions are shown at bandages creation for wounds treatment of various etiologies. Research results are recommended for usage in medical practice for optimization of wound process march