Nueva especie of Separatoppia Mahunka, 1983 (Acari, Oribatida, Oppiidae) de la India

A new oribatid mite species of the family Oppiidae –Separatoppia indica n. sp.– is described from India. This species is morphologically most similar to Separatoppia concava Ermilov & Rybalov, 2013 (Ethiopia), but differs from the latter by length of interlamellar and notogastral setae and development of humeral processes. The genus Separatoppia Mahunka, 1983 is recorded for the first time from India and the Oriental region.Se redescribe una nueva especie de ácaro oribátido de la familia Oppiidae –Separatoppia indica n. sp.– de India. La nueva especie es muy similar morfológicamente a Separatoppia concava Ermilov & Rybalov de Etiopía, pero se diferencia de ella por la longitud de las setas interlamelares y notogastrales y el desarrollo del proceso humeral. Es la primera cira del género Separatoppia Mahunka, 1983 en India y en la región oriental

Enabling in vivo measurements of nanoparticle concentrations with three-dimensional optoacoustic tomography

In this report, we demonstrate the feasibility of using optoacoustic tomography (OAT) to evaluate biodistributions of nanoparticles in animal models. The redistribution of single-walled carbon nanotubes (SWCNTs) was visualized in living mice. Nanoparticle concentrations in harvested organs were measured spectroscopically using the intrinsic optical absorption and fluorescence of SWCNTs. Observed increases in optoacoustic signal brightness in tissues were compared with increases in optical absorption coefficients caused by SWCNT accumulation. The methodology presented in this report can further be extended to calibrate the sensitivity of an optoacoustic imaging system for a range of changes in optical absorption coefficient values at specific locations or organs in a mouse body to enable noninvasive measurements of nanoparticle concentrations in vivo. Additionally, qualitative information provided by OAT and quantitative information obtained ex vivo may provide valuable feedback for advancing methods of quantitative analysis with OAT

Software for full-color 3D reconstruction of the biological tissues internal structure

A software for processing sets of full-color images of biological tissue histological sections is developed. We used histological sections obtained by the method of high-precision layer-by-layer grinding of frozen biological tissues. The software allows restoring the image of the tissue for an arbitrary cross-section of the tissue sample. Thus, our method is designed to create a full-color 3D reconstruction of the biological tissue structure. The resolution of 3D reconstruction is determined by the quality of the initial histological sections. The newly developed technology available to us provides a resolution of up to 5 - 10 {\mu}m in three dimensions.Comment: 11 pages, 8 figure

Meta-analysis of non-alcoholic fatty liver disease and electromechanical reconstruction of myocardium

The present study aimed to analyze medical databases using various scientific articles; moreover, this experiment analyzed medical databases using published scientific articles related to NAFLD, endovascular treatment, cardiac arrhythmias and conduction disorders, changes in the geometry of atria and ventricles, changes in myocardial mass volume as well as diastolic flow left and right ventricular systolic functions, coronary blood flow, analysis of the dependence of epicardial fat tissue (EFT) thickness, and the presence of chronic heart failure (CHF

Эпидемиология бокового амиотрофического склероза в Красноярском крае

Background. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that causes paralysis of muscles due to degeneration of motor neurons. According to available data, the incidence of ALS in different regions of the world is from 0.6 to 3.8 per 100,000 population per year. Data obtained during the study of the epidemiology of ALS at the regional level can be used in planning medical resources, in particular, calculating the necessary respiratory equipment and funds for nutritional support.Aim. Clinical and epidemiological analysis of ALS cases registered in the Krasnoyarsk region for the period 2018–2022.Materials and methods. A clinical and epidemiological analysis of ALS cases registered in the Krasnoyarsk region from 2018 to 2022 was conducted. To do this, we used data from the specialized office of neuromuscular pathology of the Regional Clinical Hospital in Krasnoyarsk and the Krasnoyarsk Regional Medical Information and Analytical Center. Diagnosis verification was carried out in accordance with the generally accepted El Escorial and Gold Coast criteria. The functional state and degree of neurological deficit were assessed using the ALS-FRS-R scale.Results. Over the period from 2018 to 2022, 78 cases of ALS were registered. The incidence rate was 0.54 cases per 100,000 population per year. In 2022, the prevalence rate was 1.16 cases per 100 thousand population. The time from symptom onset to diagnosis of the disease ranged from 4 to 57 months, with the average time to diagnosis being 17 months. Most patients were diagnosed with ALS when their ALS-FRS-R score decreased by 7–11 points. The division of patients into groups of rapid, moderate, and slow diagnostic correlates with life expectancy. Patients who are diagnosed quickly have a higher rate of disease progression, which results in a low life expectancy.Conclusion. The creation of specialized centers will improve the diagnosis and management of patients with ALS and plan the costs of palliative care. The increase in the incidence and detection of ALS emphasizes the need to develop new approaches to the treatment and rehabilitation of patients with ALS.Введение. Боковой амиотрофический склероз (БАС) – прогрессирующее нейродегенеративное заболевание, которое вызывает паралич мышц из-за дегенерации моторных нейронов. По имеющимся данным, заболеваемость БАС в разных регионах мира составляет от 0,6 до 3,8 случая на 100 тыс. населения в год. Данные, полученные в ходе изучения эпидемиологии БАС на региональном уровне, могут использоваться при планировании объема медицинских ресурсов, в частности для расчета необходимого респираторного оборудования и средств нутритивной поддержки.Цель работы – клинико-эпидемиологический анализ случаев БАС, зарегистрированных на территории Красноярского края за период 2018–2022 гг.Материалы и методы. Был проведен клинико-эпидемиологический анализ случаев БАС, зарегистрированных в Красноярском крае с 2018 по 2022 г. Для этого использовались данные специализированного кабинета нервномышечной патологии КГБУЗ «Краевая клиническая больница» г. Красноярска и Красноярского краевого медицинского информационно-аналитического центра. Верификация диагноза осуществлялась в соответствии с общепринятыми критериями El Escorial и Gold Coast. Функциональное состояние и степень неврологического дефицита оценивались с помощью шкалы ALS-FRS-R.Результаты. За период с 2018 по 2022 г. было зарегистрировано 78 случаев БАС. Заболеваемость составила 0,54 случая на 100 тыс. населения в год. В 2022 г. показатель распространенности составил 1,16 случая на 100 тыс. населения. Сроки диагностики заболевания варьировали от 4 до 57 мес, среднее время установления диагноза составило 17 мес. У большинства пациентов БАС был диагностирован при снижении оценки по шкале ALS-FRS-R на 7–11 баллов. Разделение пациентов на группы с быстрой, средней и медленной диагностикой коррелировало с ожидаемой продолжительностью жизни. Пациенты, у которых диагноз был установлен быстро, имеют более высокую скорость прогрессирования заболевания, что обусловливает низкую продолжительность жизни.Выводы. Создание специализированных приемов позволит улучшить диагностику и ведение пациентов с БАС и планировать затраты на паллиативную помощь. Растущая заболеваемость и выявляемость БАС подчеркивает необходимость разработки новых подходов к лечению и реабилитации больных БАС

Extracting novel facts from tables for Knowledge Graph completion

We propose a new end-to-end method for extending a Knowledge Graph (KG) from tables. Existing techniques tend to interpret tables by focusing on information that is already in the KG, and therefore tend to extract many redundant facts. Our method aims to find more novel facts. We introduce a new technique for table interpretation based on a scalable graphical model using entity similarities. Our method further disambiguates cell values using KG embeddings as additional ranking method. Other distinctive features are the lack of assumptions about the underlying KG and the enabling of a fine-grained tuning of the precision/recall trade-off of extracted facts. Our experiments show that our approach has a higher recall during the interpretation process than the state-of-the-art, and is more resistant against the bias observed in extracting mostly redundant facts since it produces more novel extractions

Features of the metabolic syndrome and type 2 diabetes mellitus in schizotypal disorder

To describe the features and mechanisms of development of metabolic syndrome, type 2 diabetes melitus and intermediate states of glycemia in psychosis the occurrence of these disorders, the values of total cholesterol, fractions of high density lipoproteins, very low density lipoproteins, triglycerides, values of atherogenic coefficient, insulinemia, С-peptidemia, insulin resistance the level of glycated hemoglobin in a sample of patients with schizophrenia and in mentally healthy individual

Substantiation of optical criterions of thermal-oxidative stability of lubricating

Research results of criteria of thermal-oxidative stability determined by different combinations of coefficient of absorption of light quantity and optical density with coefficient of evaporation and kinematic viscosity of oxygenated oil are presented. It is shown that the amount of optical density and the coefficient of evaporation divided by coefficient of relative viscosity are the most effective criteria of thermal-oxidative stability of lubricating oils described by second order polynomial with a high correlation coefficient. © Published under licence by IOP Publishing Ltd

Faunistic and taxonomic additions to the oribatid mites (Acari, Oribatida) of Cuba

The present study is based on oribatid mite materials collected from leaf litter in two forest locations in Cuba. A list of 64 species, belonging to 47 genera and 31 families, is presented. Of these, one genus and two species are recorded for the first time from the Neotropical region; 17 species, one subgenus, six genera, and two families are recorded for the first time from Cuba. Two new species of the superfamily Oripodoidea—Lagenobates fossatus Ermilov and Kontschán n. sp. (Haplozetidae) and Muliercula curvilineata Ermilov and Kontschán n. sp. (Scheloribatidae)—are described