Implementation of the Technology of Productive Learning in Teaching Disciplines of the Cycle "Programming" in the Traning of Bachelors in the Direction of "Pedagogical Education"

В статье обсуждаются вопросы методики обучения бакалавров по направлению "Педагогическое образование" в рамках традиционных дисциплин цикла "Программирование". Анализируется программа обучения содержательной линии "Алгоритмизация и программирование" в средней школе (пропедевтический курс, основная и старшая школы).The article discusses the methods of teaching bachelors in the direction of "Pedagogical education" within the traditional disciplines of the cycle "Programming". The program of teaching the content line "Algorithmization and Programming" in secondary school (propaedeutic course, basic and high school) is analyzed

Radiation-induced hydrogen transfer in metals

The paper presents processes of hydrogen (deuterium) diffusion and release from hydrogen-saturated condensed matters in atomic, molecular and ionized states under the influence of the electron beam and X-ray radiation in the pre-threshold region. The dependence is described between the hydrogen isotope release intensity and the current density and the electron beam energy affecting sample, hydrogen concentration in the material volume and time of radiation exposure to the sample. The energy distribution of the emitted positive ions of hydrogen isotopes is investigated herein. Mechanisms of radiation-induced hydrogen transfer in condensed matters are suggested

Low-frequency dynamics of disordered XY spin chains and pinned density waves: from localized spin waves to soliton tunneling

A long-standing problem of the low-energy dynamics of a disordered XY spin chain is re-examined. The case of a rigid chain is studied where the quantum effects can be treated quasiclassically. It is shown that as the frequency decreases, the relevant excitations change from localized spin waves to two-level systems to soliton-antisoliton pairs. The linear-response correlation functions are calculated. The results apply to other periodic glassy systems such as pinned density waves, planar vortex lattices, stripes, and disordered Luttinger liquids.Comment: (v2) Major improvements in presentation style. One figure added (v3) Another minor chang

Multifrequency EPR and DENR of polyacetylene composite

The organo-inorganic composite MoCl1.9 ± 0.1(C 30 ± 1H30 ± 1), a product of interaction of MoCl5 with C2H2, has been studied by X- and W-band EPR, double electron nuclear resonance, and W-band electron spin echo spectroscopy. The composite consists of nanosized organometallic molybdenum clusters in the polyacetylene matrix. It has been shown that the composite contains three types of magnetic centers: the first is related to the existence of paramagnetic molybdenum atoms in the polyacetylene matrix, and the other two are paramagnetic defects of the matrix. © 2013 Pleiades Publishing, Ltd

Mechanistic aspects of reactions of triphenylphosphine with electron-deficient alkenes in acetic acid solution

Kinetic data provide evidence that proton transfer to the carbanion centre of a phosphonium zwitterion is the rate-determining step in quarternization reactions of triphenylphosphine with electron-deficient alkenes in acetic acid solution. This conclusion is based on the third-order rate equation, the reactivity of the alkenes, and solvent isotope effects in deuteroacetic acid. Copyright © 2013 John Wiley & Sons, Ltd

Адъювантная внутрипузырная химиотерапия с аквакомплексом глицеросольвата титана в сравнении с БЦЖ-терапией у больных немышечно-инвазивным раком мочевого пузыря высокого риска

Objective: to compare recurrence rate, progression rate and recurrence-free survival in patients with high-risk non-muscle-invasive bladder cancer (NMIBC) after adjuvant intravesical chemotherapy (IVCT) with titanium glycerosolvate aquacomplex (TGA) versus intravesical BCG therapy.Material and methods. In a retrospective multicenter clinical study initially were included 126 patients with NMIBC. Of all 126 patients, 94 patients with high-risk NMIBC were selected and divided into 2 groups using a pseudo randomization with propensity score matching to minimize systematic differences in the process of forming groups. The treatment group (n = 55) consisted of patients with high-risk NMIBC who received a 6-week course of adjuvant IVCT with TGA. In the control group (n = 39) patients received an induction 6-week course of adjuvant intravesical BCG therapy, 19 (49 %) of 39 patients received maintenance therapy. Both methods were compared according to recurrence rate, progression rate and recurrence-free survival. Significance of difference was set at p <0.05.Results. The compared groups of patients were well balanced in terms of clinical and morphological characteristics and the main risk factors for recurrence and progression of non-muscle-invasive bladder cancer, no significant differences were found between the groups (p >0.5). The recurrence rate in treatment and control groups was 33 % and 23 %, respectively (p = 0.31). The disease progression was observed in 1 (2 %) patient in the treatment group and in 4 (13 %) patients in the control group (p = 0.08). The median disease-free survival in both groups of patients was not reached at the time of analysis. Three- and five-year recurrence-free survival in the treatment group of patients were 71 % and 62 %, respectively; in the control group — 76 % and 72 %, respectively. There were no significant differences between recurrence-free-survival curves of the treatment and control groups (p = 0.58).Conclusion. Adjuvant IVCT with TGA has demonstrated a clinical effectiveness comparable to intravesical BCG therapy and it can be used as an alternative method of treatment in patients with high-risk NMIBC.Цель исследования — сравнить безрецидивную выживаемость, частоту рецидивов и прогрессирования заболевания у больных немышечно-инвазивным раком мочевого пузыря (НМИРМП) высокого риска после адъювантной внутрипузырной химиотерапии (ВПХТ) с аквакомплексом глицеросольвата титана (АГТ) в сравнении с внутрипузырной терапией бациллой Кальметта-Герена (БЦЖ).Материалы и методы. В ретроспективное мультицентровое сравнительное клиническое исследование исходно включены 126 пациентов с НМИРМП. Из них с использованием метода псевдорандомизации (propensity score matching) отобраны 94 пациента с НМИРМП высокого риска, которые были разделены на 2 группы: основную и контрольную. Основную группу (n = 55) составили больные, получившие 6-недельный курс адъювантной ВПХТ с АГТ. Пациенты контрольной группы (n = 39) получили индукционный 6-недельный курс адъювантной внутрипузырной БЦЖ-терапии в режиме 1 инстилляция в неделю, у 19 (49 %) из 39 больных проводилось поддерживающее лечение в срок от 2 до 16 мес. Сравнение эффективности различных методик адъювантной внутрипузырной терапии выполняли по показателям безрецидивной выживаемости, частоте рецидивов и прогрессирования заболевания. Достоверность различий устанавливали при уровне значимости p <0,05.Результаты. Сравниваемые группы больных были хорошо сбалансированы по клинико-морфологическим характеристикам и основным факторам риска рецидива и прогрессирования НМИРМП, достоверных различий между ними не выявлено (p >0,5). Частота рецидивов заболевания в основной и контрольной группах составила 33 и 23 % соответственно (р = 0,31). Прогрессирование заболевания установлено у 1 (2 %) больного в основной группе и у 4 (13 %) больных в контрольной группе (p = 0,08). Медиана безрецидивной выживаемости в обеих группах на момент проведения анализа не достигнута. Показатели 3- и 5-летней безрецидивной выживаемости в основной группе составили 71 и 62 %, в контрольной группе - 76 и 72 % соответственно. При сравнении кривых безрецидивной выживаемости основной и контрольной групп достоверных различий между ними не выявлено (p = 0,58).Заключение. Адъювантная ВПХТ с АГТ позволяет получить сопоставимые с внутрипузырной БЦЖ-терапией основные показатели эффективности и может применяться в качестве альтернативного метода лечения у больных НМИРМП высокого риска

Writing Russia's future: paradigms, drivers, and scenarios

The development of prediction and forecasting in the social sciences over the past century and more is closely linked with developments in Russia. The Soviet collapse undermined confidence in predictive capabilities, and scenario planning emerged as the dominant future-oriented methodology in area studies, including the study of Russia. Scenarists anticipate multiple futures rather than predicting one. The approach is too rarely critiqued. Building on an account of Russia-related forecasting in the twentieth century, analysis of two decades of scenarios reveals uniform accounts which downplay the insights of experts and of social science theory alike

PECULIARITIES OF UNIVERSITY PARTNERSHIP NETWORKS PRESENTATIONS

The article tests out the criteria for comparing data on activity of partnership networks of higher education institutions presented on their websites. The authors give a comparative analysis of self-presentations provided by the three world's top universities - Massachusetts Institute of Technology, Cambridge University and Imperial College London. Considerable attention is focused on peculiarities of presentation of network partners, interactions with and between partners, and also prospects for development of partnership networks. The proposed criteria have proved effective in identifying common features and differences in the way higher education institutions supply information about their partnership networks