1,828 research outputs found

    Comparative Assessment of the Factors and Conditions of the Formation of the Neoindustrial Social State in Russia and Germany

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    Russia and Germany are traditionally reputed as countries with socially oriented economies. Namely, these countries are also close by the index of the share of real sector of economy at GDP. And however, Germany is a founder of social market household largely defined its leadership in world economy, in current conditions of crisis of “the state of general welfare” the search of a new model of development for Germany is also important as for Russia stood on the way of modernization and neo-industrialization. In the article, the hypothesis about forming of the new model of development uniting the social orientation of economy, processes of neoindustrialization, and globalization is made. At the same time, the social orientation is the main aim of socio-economic development, neo-industrialization is a way to achieve it, and globalization is a criterion presupposing more effective use of resources. Theoretical backgrounds of development of “social state” are generalized in the works of German and Russian classics put the backgrounds of economic humanism, it has allowed to prove the fatality of modernization process without considering of deep mental backgrounds and civilization codes of the nation development. The methodological approaches to development of a new model of neo-industrial social state with emphasizing different levels: global, national, local, individual are worked out; and the technique for estimation of factors and conditions of its development is proposed. The technique is tested on the example of Russia and Germany. The comparative analysis conducted has allowed to make the conclusion about similarity of target guidelines, initial conditions, problems and ways of their solving in these countries, that is to be considered both in a strategy and a policy of socio-economic development of these countries and by their international partnership

    Targeting the principle implementation in the system of social support

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    Purpose: The article aims to identify the actual problems of implementing the principle of targeting in the social protection system in Russia and to develop a set of measures to transform the mechanism of its provision based on a differentiated approach, which implies not only differences in the size of social transfers, but also on various forms of such support. Design/Methodology/Approach: As the basic approaches of the study there were chosen the theory of social investment and the conception of result-based budgeting. The study suggested the development of a more effective financial support system, the substantiation of a differentiated approach to the organization of a social system based on a single method by determining the degree of financial vulnerability of citizens and the development of methodological recommendations on the use of financial instruments to strengthen the targeting of social protection of needy citizens. Findings: The article substantiates that the necessary condition for the transformation of the social protection system to strengthen the social and financial security of needy citizens is the development of a differentiated approach in the provision of social support measures. Practical Implications: The results of the study can be implemented into the management of social protection in order to improve its efficiency and effectiveness by using the targeting of social transfers based on clear criteria of need, the differentiated approach implementation in determining the measures of social support through the use of "map of social support of citizens", expanding the application of social contract technology. Originality/Value: The set of measures proposed in the study will make it possible not only to adjust and direct social support to really needy recipients and to differentiate the volume of the support provided, but also to create conditions for the recipients of targeted protection to self-sufficiency, which, in turn, will contribute to the poverty reduction.peer-reviewe

    Widespread presence of "bacterial-like" PPP phosphatases in eukaryotes

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    BACKGROUND: In eukaryotes, PPP (protein phosphatase P) family is one of the two known protein phosphatase families specific for Ser and Thr. The role of PPP phosphatases in multiple signaling pathways in eukaryotic cell has been extensively studied. Unlike eukaryotic PPP phosphatases, bacterial members of the family have broad substrate specificity or may even be Tyr-specific. Moreover, one group of bacterial PPPs are diadenosine tetraphosphatases, indicating that bacterial PPP phosphatases may not necessarily function as protein phosphatases. RESULTS: We describe the presence in eukaryotes of three groups of expressed genes encoding "non-conventional" phosphatases of the PPP family. These enzymes are more closely related to bacterial PPP phosphatases than to the known eukaryotic members of the family. One group, found exclusively in land plants, is most closely related to PPP phosphatases from some α-Proteobacteria, including Rhizobiales, Rhodobacterales and Rhodospirillaceae. This group is therefore termed Rhizobiales / Rhodobacterales / Rhodospirillaceae-like phosphatases, or Rhilphs. Phosphatases of the other group are found in Viridiplantae, Rhodophyta, Trypanosomatidae, Plasmodium and some fungi. They are structurally related to phosphatases from psychrophilic bacteria Shewanella and Colwellia, and are termed Shewanella-like phosphatases, or Shelphs. Phosphatases of the third group are distantly related to ApaH, bacterial diadenosine tetraphosphatases, and are termed ApaH-like phosphatases, or Alphs. Patchy distribution of Alphs in animals, plants, fungi, diatoms and kinetoplasts suggests that these phosphatases were present in the common ancestor of eukaryotes but were independently lost in many lineages. Rhilphs, Shelphs and Alphs form PPP clades, as divergent from "conventional" eukaryotic PPP phosphatases as they are from each other and from major bacterial clades. In addition, comparison of primary structures revealed a previously unrecognised (I/L/V)D(S/T)G motif, conserved in all bacterial and "bacterial-like" eukaryotic PPPs, but not in "conventional" eukaryotic and archaeal PPPs. CONCLUSIONS: Our findings demonstrate that many eukaryotes possess diverse "bacterial-like" PPP phosphatases, the enzymatic characteristics, physiological roles and precise evolutionary history of which have yet to be determined
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