Morphological characteristics of the pancreatic heterotopia in the major duodenal papilla

The anatomical, morphometrical, histological and immunohistochemical studies of the major duodenal papilla were performed on the materials of 327 autopsy cases. The pancreatic heterotopia was revealed in 14,7% cases. This abnormality was associated with an existence of gallstone disease. More often the heterotopic pancreatic tissue was detected in the medial wall of the major duodenal papilla and its septum. Exocrine, complete and ductular histological variants of pancreatic heterotopia were revealed. The latter existed either as a morphological basis of papillary adenomas with cellular hyperplasia possessing smooth muscle immunophenotype, or as the result of atrophy and sclerosis of the exocrine heterotopic structure

Effect of carbamylated darbepoetin administration at different doses on the thymus and spleen structure of rats

In this article, the morphological features of the structure of the thymus and spleen under the influence of carbamylated darbepoetin in different doses were studied. The material for the study was 40 white male rats of the Wistar bree

Rare case of type II glycogen storage disease

The article presents information about a rare case of Pompe disease. It is a glycogen storage disease. During the third screening of a pregnant woman, the ultrasonography of the fetus’s heart revealed the myocardial hypertrophy of the left ventricle perceived as posthypoxic. After delivery, the newborn underwent the ultrasound examination and molecular genetic studies. Firstly, the hepatomegaly and cardiomegaly were diagnosed. Then an infantile form of Pompe disease was found. The patient got enzyme replacement therapy without positive result. The death occurred at the age of 2 years and 5 months as a result of cardiovascular disease failure. Macroscopically, the sizes of the internal organs were increased. The microscopic examination demonstrated glycogen deposition in the myocardium, skeletal muscles, mucous membranes of the organs of the gastrointestinal tract, liver, kidney, spleen and adrenal gland

Pecularities of the influence of cyclophosphamide and imunophan on the processes of apoptosis and necrosis in Peyers patches of rats small intestine

In this article, we studied the peculiarities of cyclophosphamide and imunofan effect on the processes of apoptosis and necrosis in Peyers patches of the rats small intestine. The study was conducted on 18 white mature rats, which were divided into three group

Morphometric study of hippocampal neurons in chronic immobilization stress

Hippocampus ensures the implementation of the memory mechanisms, behavioral reactions, including avoidance of stress, aversive effects etc. The study was performed on the material of 20 male Wistar rats weighing 220-250 g, 10 of which were intact control group and 10 were experimental group, in which chronic immobilization stress was simulated. We determined the relative number of neurons in multiple fields of view on the total area of the pyramidal and polymorphic layers of CA1 and CA3 regions (further recalculated per 10,000 μm), larger and smaller diameters of neuron’s bodies, their perimeters and areas with diameters of nuclei and nucleoli, nuclear-cytoplasmic rati

Fractional Models of Cosmic Ray Acceleration in the Galaxy

Possible formulations of the problem of cosmic rays acceleration in the interstellar galactic medium are considered with the use of fractional differential equations. The applied technique has been physically justified. A Fermi result has been generalized to the case of the acceleration of particles in shock waves in the supernovae remnants fractally distributed in the Galaxy.Comment: 10 page

Rare branching pattern of the subscapular artery

Our work presents a previously undescribed branching pattern of the right subscapular artery. It branched into the thoracodorsal, the circumflex scapular, the profunda brachii, and the anterior and posterior circumflex humeral arteries. The described branching pattern of the subscapular artery can be important and essential for surgeons and radiologist

Adenomatous lesions of the major duodenal papilla in conjunction with pancreatic heterotopia

The study was carried out on the material of 327 pathoanatomical autopsies taking into account the sex, age, clinical data, pathoanatomical, and clinical diagnoses. The material is divided into two groups: The 1st group - without an ectopic pancreatic tissue in the major duodenum papilla (279 cases) and the 2nd group - with different variants of ectopic pancreatic tissue (48 cases). In each of them, the distribution was carried out according to sex, age, and cause of deat

Study to Investigate the anti-inflammatory effect of Codelac® Broncho with Thymus Serpyllum (elixir) in comparison with reference drug Fenspiride (syrup) using accute carrageenan-induced paw inflammation model

Evaluation of anti-inflammatory action of Codelac® Broncho with Thymus Serpyllum (elixir) in comparison with Fenspiride was carried out on the model of acute carrageenan inflammation of the paws in rats. As a result of the study, it turned out that obtained data indicate a more pronounced anti-inflammatory activity of Codelac® Broncho with Thymus Serpyllum in comparison with Fenspiride, on the model of acute carrageenan inflammation of the paw in rat

Evaluation of morphological and histological changes of aggregated lymph nodes in the small intestine after Imofan treatment in immunosuppressed rats

The present study aimed to investigate morphological features of the aggregated lymphoid nodules of the small intestine after the Imunofan administration following Cyclophosphamide-induced immunosuppressio