155 research outputs found

    Surface Tension of Seawater

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    New measurements and a reference correlation for the surface tension of seawater at atmospheric pressure are presented in this paper. Surface tension of seawater was measured across a salinity range of 20 ⩽ S ⩽ 131 g/kg and a temperature range of 1 ⩽ t ⩽ 92 °C at atmospheric pressure using the Wilhelmy plate method. The uncertainty within measurements varied from 0.18 to 0.37 mN/m with the average uncertainty being 0.22 mN/m. The experimental procedures were validated with tests conducted on ACS reagent grade water and aqueous sodium chloride solutions. Literature data and present measurements were evaluated and a reference correlation was developed expressing surface tension of seawater as a function of temperature and salinity. The average absolute percentage deviation between measurements and the correlation was 0.19% while the maximum deviation was 0.60%.Center for Clean Water and Clean Energy at MIT and KFUPM (Project R13-CW-10

    Annealing-induced property improvements in 2-14-1 powders produced by inert gas atomization

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    Social Transmission and the Spread of Modern Contraception in Rural Ethiopia

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    Socio-economic development has proven to be insufficient to explain the time and pace of the human demographic transition. Shifts to low fertility norms have thus been thought to result from social diffusion, yet to date, micro-level studies are limited and are often unable to disentangle the effect of social transmission from that of extrinsic factors. We used data which included the first ever use of modern contraception among a population of over 900 women in four villages in rural Ethiopia, where contraceptive prevalence is still low (<20%). We investigated whether the time of adoption of modern contraception is predicted by (i) the proportion of ever-users/non ever-users within both women and their husbands' friendships networks and (ii) the geographic distance to contraceptive ever-users. Using a model comparison approach, we found that individual socio-demographic characteristics (e.g. parity, education) and a religious norm are the most likely explanatory factors of temporal and spatial patterns of contraceptive uptake, while the role of person-to-person contact through either friendship or spatial networks remains marginal. Our study has broad implications for understanding the processes that initiate transitions to low fertility and the uptake of birth control technologies in the developing world

    The Evolution of Religion: How Cognitive By-Products, Adaptive Learning Heuristics, Ritual Displays, and Group Competition Generate Deep Commitments to Prosocial Religio

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    Understanding religion requires explaining why supernatural beliefs, devotions, and rituals are both universal and variable across cultures, and why religion is so often associated with both large-scale cooperation and enduring group conflict. Emerging lines of research suggest that these oppositions result from the convergence of three processes. First, the interaction of certain reliably developing cognitive processes, such as our ability to infer the presence of intentional agents, favors—as an evolutionary by-product—the spread of certain kinds of counterintuitive concepts. Second, participation in rituals and devotions involving costly displays exploits various aspects of our evolved psychology to deepen people's commitment to both supernatural agents and religious communities. Third, competition among societies and organizations with different faith-based beliefs and practices has increasingly connected religion with both within-group prosociality and between-group enmity. This connection has strengthened dramatically in recent millennia, as part of the evolution of complex societies, and is important to understanding cooperation and conflict in today's world

    Longan-inspired chitosan-pectin core-shell hydrogel beads for oral delivery of biodrugs to enhance osteoporosis therapy

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    Funding Information: This work was supported by Ton Duc Thang University. This work was also supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MSIT) (NRF-2023R1A2C1005904). E.-S.J. is incredibly grateful for the research grant from the Korean Ministry of Education, Science & Technology (2016R1D1A3B0201175615), the Korean Health Technology R&D Project (HP23C0260) through the Korean Health Industry Development Institute (KHIDI) funded by the Ministry of Health and Welfare, and the Innovative Human Resource Development for Local Intellectualization Support Program (IITP-2025-RS-2020-II201612) through the Institute of Information & Communications Technology Planning & Evaluation (IITP) funded by the Korean government (MSIT), Republic of Korea. The Basic Science Research Program supported this research through the National Research Foundation of Korea (NRF), funded by the Ministry of Education (NRF-2022R1I1A1A01068693). Publisher Copyright: © 2025 The AuthorsOsteoporosis, a common disorder, is characterized by a systemic reduction in bone mass and structural integrity, resulting in brittle bones. Reducing bone loss and enhancing bone density through oral administration of biopharmaceuticals provides significant advantages, including convenience and non-invasiveness for patients. However, challenges such as poor absorption and enzymatic degradation necessitate the development of innovative drug delivery systems. This research introduces a core-shell hydrogel system inspired by the natural architecture of Longan fruit, constructed from pectin and chitosan biopolymers, designed to create biocapsules and sustain the release of biodrugs. In this system, salmon calcitonin (sCT) was encapsulated within mesoporous silica nanoparticles (MSNs) and incorporated into the core of the beads. The synthesis of the core-shell hydrogel beads was carefully regulated by adjusting the immersion time and concentration of the crosslinker. The hydrogel beads demonstrated durability, with the pectin shell effectively preventing rapid degradation in the stomach, while the chitosan layer enhanced adhesion to the intestinal walls, safeguarded sCT, and enabled sustained drug release over an extended period of up to 30 h. Furthermore, biocompatibility tests indicated minimal cytotoxicity and hemolysis. Cellular uptake assays demonstrated that the core-shell beads effectively encapsulated sCT and ensured its prolonged release to CT-26 cells. This study presents a promising platform for oral sCT delivery, offering enhanced efficacy, patient compliance, and a potential replacement for injection-based therapies.publishersversionpublishe

    Mutually Positive Regulatory Feedback Loop between Interferons and Estrogen Receptor-α in Mice: Implications for Sex Bias in Autoimmunity

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    gene) and stimulates expression of target genes. female mice had relatively higher steady-state levels of mRNAs encoded by the IFN and ERα-responsive genes as compared to the age-matched males.Our observations identify a novel mutually positive regulatory feedback loop between IFNs and ERα in immune cells in mice and support the idea that activation of this regulatory loop contributes to sex bias in SLE

    Social Closure and the Evolution of Cooperation via Indirect Reciprocity

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    Direct and indirect reciprocity are good candidates to explain the fundamental problem of evolution of cooperation. We explore the conditions under which different types of reciprocity gain dominance and their performances in sustaining cooperation in the PD played on simple networks. We confirm that direct reciprocity gains dominance over indirect reciprocity strategies also in larger populations, as long as it has no memory constraints. In the absence of direct reciprocity, or when its memory is flawed, different forms of indirect reciprocity strategies are able to dominate and to support cooperation. We show that indirect reciprocity relying on social capital inherent in closed triads is the best competitor among them, outperforming indirect reciprocity that uses information from any source. Results hold in a wide range of conditions with different evolutionary update rules, extent of evolutionary pressure, initial conditions, population size, and density
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