440 research outputs found
Mining High Dimensional Web Content With Sentimental Analysis: A Proactive Approach
Sentiment analysis or opinion mining has a humongous scope in the field of digital marketing. Many research ideas have evolved in this field of engineering over the past decades. The major task of proposing sentiment analysis in mining is to systematize the detection of opinions, attitudes and the feelings expressed. These approaches however have some setback in certain scenarios. Rather than directly expressing the feelings sometimes a person might use diverse strategies to express emotions which might be positive, negative or neutral. One word which was viewed positive in a scenario might be regarded as negative in another situation. Such circumstances would interrogate the reliability of sentimental analysis. Our researches aim at alleviating the challenges in sentimental analysis and deliver a tool that is effective and reliable
Indian railway track analysis for displacement and vibration pattern estimation
This paper presents the dynamic response of the Indian Railway track. Two track models are considered for the dynamic response in terms of vertical displacement and acceleration at different wheel speeds, keeping the moving point load at constant magnitude. The rail is treated as a beam either on viscoelastic foundation or on the discrete elastic support system. The governing equation is implemented in finite element analysis using ANSYS 14.0. For the validation of result from system equation are compared with those available in published literature and the maximum deviation for displacement at the midpoint of rail is found to be within 5 %. Different wheel speed generates variation in displacement and acceleration of the rail track. The study can be viewed as the foundation for the comparison of FEA based simulation of rail track to specify its dynamic response useful to provide better safety and comfort to commuters
Physicochemical and biological studies of a new erythromycin derivate - erythromycin folate
Se preparó un derivado nuevo de la eritromicina, el folato de eritromicina, y se evaluaron sus propiedades
fisicoquímicas y biológicas. El derivado presenta una buena solubilidad en metanol, etanol y
propileno glicol. Los valores de los coeficientes de partición, que fueron 1,12 y 1,10 en sistemas de
cloroformo/agua y octanol/agua respectivamente, indican que probablemente se distribuya bien in vivo.
La potencia in vitro del derivado, 716 μg/mg, es mayor que la de derivados existentes como el estolato
de eritromicina, el estearato de eritromicina, el etil sucinato de eritromicina, el gluceptato de eritromicina
y el lactobionato de eritromicina. Las concentraciones inhibitorias mínimas in vitro del derivado son
menores que las de la base frente a Klebsiella pneumonia, Pseudomonas aeruginasa, Bacillus pumilis y
Escherichia coli. Los parámetros farmacocinéticos in vivo del derivado en conejos son los siguientes:
la vida media de eliminación, t½ es de 117,45 min. para el derivado y de 150,45 min. para la base de
eritromicina utilizada como estándar de referencia. El volumen de distribución Vd del derivado y de la
base de eritromicina es de 177,56 % y 352,20 % respectivamente. Los resultados de la investigación indican que el folato de eritromicina tiene un gran potencial en aplicaciones clínicas posibles.A new derivative of erythromycin, Erythromycin folate was prepared and its physicochemical and
biological properties were evaluated. The derivative has good solubility in methanol, ethanol and propylene
glycol. The partition coefficient values of 1.12 and 1.10 in chloroform/water and octanol/water systems
respectively indicate that the derivative will probably distribute well in vivo. The in vitro potency of
the derivative, 716 μg/mg, is higher than the existing derivatives like erythromycin estolate, erythromycin
stearate, erythromycin ethyl succinate, erythromycin gluceptate, and erythromycin lactobionate. The in
vitro Minimum Inhibitory Concentrations are less for the derivative than the base against Klebsiella
pneumonia, Pseudomonas aeruginasa, Bacillus pumilis and Escherichia coli. The in vivo pharmacokinetic
parameters of the derivative in rabbits are as follows: the elimination half life, t½ is 117.45 min for the
derivative while it is 150.45 min for erythromycin base the reference standard. The volume of distribution
Vd is 177.56% and 352.20% for the derivative and erythromycin base respectively. The results of the present investigations indicate that erythromycin folate has a high potential for possible clinical application.La University Grants Commission (UGC) de la India ha financiado este proyect
Effect of FCNC mediated Z boson on lepton flavor violating decays
We study the three body lepton flavor violating (LFV) decays , and the semileptonic decay in the flavor changing neutral current (FCNC) mediated boson
model. We also calculate the branching ratios for LFV leptonic B decays,
, , and the
conversion of muon to electron in Ti nucleus. The new physics parameter space
is constrained by using the experimental limits on and
. We find that the branching ratios for and processes could be as large as and . For other LFV B decays the branching ratios are found to be too
small to be observed in the near future.Comment: 15 pages, 8 figures, typos corrected, one more section added, version
to appear in EPJ
SM with four generations: Selected implications for rare B and K decays
We extend our recent work and study implications of the Standard Model with
four generations (SM4) for rare B and K decays. We again take seriously the
several 2-3 anomalies seen in B, decays and interpret them in
the context of this simple extension of the SM. SM4 is also of course of
considerable interest for its potential relevance to dynamical electroweak
symmetry breaking and to baryogenesis. Using experimental information from
processes such as , and mixings, indirect
CP-violation from etc along with oblique corrections, we
constrain the relevant parameter space of the SM4, and find of about
400-600 GeV with a mixing angle in the range of about
(0.05 to 1.4) and with an appreciable CP-odd associated phase,
are favored by the current data. Given the unique role of the CP asymmetry in
due to its gold-plated nature, correlation of that with
many other interesting observables, including the semileptonic asymmetry
() are studied in SM4. We also identify several processes, such as , etc, that are significantly
different in SM4 from the SM. Experimentally the very distinctive process
is also discussed; the branching ratio can be larger or
smaller than in SM, , by a factor of
.Comment: v2: 49 pages, 20 eps figures, Corrected some typos, added few
references and minor changes with regard to direct CP in K pi. Also some
added information to facilitate direct comparison with Buras et al,
arXiv:1002.2126
Constraints on the nonuniversal Z^\prime couplings from B\to\pi K, \pi K^{\ast} and \rho K Decays
Motivated by the large difference between the direct CP asymmetries
and , we
combine the up-to-date experimental information on ,
and decays to pursue possible solutions with the nonuniversal
model. Detailed analyses of the relative impacts of different
types of couplings are presented in four specific cases. Numerically, we find
that the new coupling parameters, and with a common
nontrivial new weak phase , which are relevant to the
contributions to the electroweak penguin sector
and , are crucial to the observed " puzzle". Furthermore,
they are found to be definitely unequal and opposite in sign. We also find that
can put a strong constraint on the new
couplings, which implies the contributions to the coefficient of
QCD penguins operator involving the parameter required.Comment: 27 pages, 6 figures. References and a note adde
Double-Lepton Polarization Asymmetries and Branching Ratio in B \rar K_{0}^{*}(1430) l^+ l^- transition from Universal Extra Dimension Model
We investigate the B \rar K_{0}^{*}(1430) l^+ l^- transition in the
Applequist-Cheng-Dobrescu model in the presence of a universal extra dimension.
In particular, we calculate double lepton polarization asymmetries and
branching ratio related to this channel and compare the obtained results with
the predictions of the standard model. Our analysis of the considered
observables in terms of radius of the compactified extra-dimension as the
new parameter of the model show a considerable discrepancy between the
predictions of two models in low values.Comment: 12 Pages, 15 Figures and 1 Tabl
Goldstone Bosons in Effective Theories with Spontaneously Broken Flavour Symmetry
The Flavour Symmetry of the Standard Model (SM) gauge sector is broken by the
fermion Yukawa couplings. Promoting the Yukawa matrices to scalar spurion
fields, one can break the flavour symmetry spontaneously by giving appropriate
vacuum expectation values (VEVs) to the spurion fields, and one encounters
Goldstone modes for every broken flavour symmetry generator. In this paper, we
point out various aspects related to the possible dynamical interpretation of
the Goldstone bosons: (i) In an effective-theory framework with local flavour
symmetry, the Goldstone fields represent the longitudinal modes for massive
gauge bosons. The spectrum of the latter follows the sequence of
flavour-symmetry breaking related to the hierarchies in Yukawa couplings and
flavour mixing angles. (ii) Gauge anomalies can be consistently treated by
adding higher-dimensional operators. (iii) Leaving the U(1) factors of the
flavour symmetry group as global symmetries, the respective Goldstone modes
behave as axions which can be used to resolve the strong CP problem by a
modified Peccei-Quinn mechanism. (iv) The dynamical picture of flavour symmetry
breaking implies new sources of flavour-changing neutral currents, which arise
from integrating out heavy scalar spurion fields and heavy gauge bosons. The
coefficients of the effective operators follow the minimal-flavour violation
principle.Comment: 27 pages, abstract and introduction extended, more detailed
discussion of heavy gauge boson spectrum and auxiliary heavy fermions,
outline restructured. Matches version to be published in JHE
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