Current issues of anti-epidemic readiness of a Russian Federation region for emergency situations associated with infectious diseases dangerous for humans. Report 2. Priority directions of anti-epidemic readiness

The purpose of this study was to determine priority directions of anti-epidemic readiness of the Russian Federation Region for emergency situations associated with infectious diseases dangerous for humans, at the present stage. Readiness of the Russian Federation region for emergency situations associated with infectious diseases dangerous for humans (anti-epidemic readiness) implies a set of preventive and anti-epidemic measures, implementation of relevant management decisions at the Regional level, which aim to ensure the safety of people living (temporarily located) in conditions of epidemiological risks. Anti-epidemic readiness is provided through targeted distribution of logistics, human resources, scientific methods, and informational resources of public health of the region, taking into account the priority of the organization of preventive measures especially for those infectious diseases that define dominant epidemiological risk in a particular municipality. Efficient use of resources is not possible without administrative, legal and financial support. As the result of the research priority directions of anti-epidemic readiness of the Russian Federation region for emergency situations associated with infectious diseases dangerousfor humans, taking into account the dominant epidemiological risks, are formulated

CURRENT ISSUES OF ANTI-EPIDEMIC READINESS OF A RUSSIAN FEDERATION REGION FOR EMERGENCY SITUATIONS ASSOCIATED WITH INFECTIOUS DISEASES DANGEROUS FOR HUMANS. REPORT 1. CONCEPTS, TERMS, DEFINITIONS

In the last decade outbreaks and epidemics of infectious diseases dangerous for humans cause tension epidemiological situation in the world and in the Russian Federation. Epidemic manifestation of these diseases has symptoms of emergency situations and requires the use of additional forces and means of Public Health, as well as administrative, legal and financial support. The purpose of this study is formulation of the concept of "public health emergency situations associated with diseases dangerous for humans". In considering of definitions "emergency situation", "disease" and "event" in international and national law, the thesis is confirmed that epidemic manifestation of infectious diseases dangerous for humans, are signs of an emergency. In addition, the interpretation of these terms focuses on the distinction between potential risk and its actual implementation. Consequently, the threat of public health emergency situations should be viewed from the risk methodology, by which we proposed to evaluate internal and external epidemiological risks and to define its dominance for each municipality of the Russian Federation Region. Infectious diseases dangerous for humans which able to cause public health emergency situations, can be divided into three groups. 1. Diseases that form the external epidemiological risk - dangerous infectious diseases requiring measures for sanitary protection of the territory of the Russian Federation. 2. Diseases that form the internal epidemiological risk - dangerous infectious diseases, registration both single and mass indigenous events requires emergency response and using of additional forces and means of public health of the Region. 3. Infectious diseases of importance in regional pathology, prevention of which is to implement long-term programs. In the framework of this paper the definition of "public health emergency situations associated with diseases dangerous for humans" is proposed. It focuses on the feasibility of upgrading approaches to priority directions of anti-epidemic readiness of the Russian Federation Region, taking into account the probability of epidemiological risks

Detecting the (Quasi-)Two-Body Decays of τ\tau Leptons in Short-Baseline Neutrino Oscillation Experiments

Novel detector schemes are proposed for the short-baseline neutrino experiments of next generation, aimed at exploring the large-$\Delta m^2$ domain of \omutau oscillations in the appearance mode. These schemes emphasize good spectrometry for charged particles and for electromagnetic showers and efficient reconstruction of \ypi_gg decays. The basic elements are a sequence of relatively thin emulsion targets, immersed in magnetic field and interspersed with electronic trackers, and a fine-grained electromagnetic calorimeter built of lead glass. These elements act as an integral whole in reconstructing the electromagnetic showers. This conceptual scheme shows good performance in identifying the $\tau$ (quasi-)two-body decays by their characteristic kinematics and in selecting the electronic decays of the $\tau$.Comment: 34 pages, 8 figure

CREATION OF AN ACTIVE ELEMENT OF A NEW BRANCH OF KNOWLEDGE ECONOMY – THE DIGITAL ECONOMY

The brief analysis of the development of L. V. Kantorovich's ideas in the works of his students and followers has been presented. This intellectual base can be used in solving the problems of digital transformation, digitalization, creation of digital platforms and their ecosystems in the digital economy. It has been proposed to create an active element of a new branch of knowledge economy – the digital economy – in the form of “Association of departments of applied mathematics of economic and managerial profiles of Russian Universities”, the advisability of this decision has been substantiated. The Association will allow you to simultaneously conduct research on a wide range of topical issues of the digital economy, optimally form creative teams and expert groups, carry out constant scientific communication in real time, and connect talented young people to research between the postgraduate students, graduate students, and students. Working together in the structure of the Association, the departments of higher education institutions will be able to show the effect of synergy and achieve much more results in their activities. The Association has a great educational potential, which can be effectively used to improve the various levels of personnel potential of management systems. Creating associations in the field of breakthrough technologies is the best way to activate Russia's intellectual potential

Recombinant small heat shock protein from Acholeplasma laidlawii increases the Escherichia coli viability in thermal stress by selective protein rescue

© 2017, Pleiades Publishing, Inc.In both prokaryotes and eukaryotes, the survival at temperatures considerably exceeding the optimum is supported by intense synthesis of the so-called heat shock proteins (HSPs), which act to overcome the adverse effects of heat stress. Among mycoplasmas (class Mollicutes), which have significantly reduced genomes, only some members of the Acholeplasmataceae family possess small HSPs of the α-crystallin type. Overproduction of a recombinant HSP IbpA (Hsp20) from the free-living mycoplasma Acholeplasma laidlawii was shown to increase the resistance of Escherichia coli to short-term heat shock. It has been long assumed that IbpA prevents protein aggregation and precipitation thereby increasing viability of E. coli cells. Several potential target proteins interacting with IbpA under heat stress were identified, including biosynthetic enzymes, enzymes of energy metabolism, and components of the protein synthesis machinery. Statistical analysis of physicochemical properties indicated that IbpA interaction partners significantly differ in molecular weight, charge, and isoelectric point from other members of the E. coli proteome. Upon shortterm exposure to increased temperature, IbpA was found to preferentially interact with high-molecularweight proteins having a pI of about 5.1, significantly lower than the typical values of E. coli proteins

GIS TOOLS IN THE WORK OF EPIDEMIOLOGICAL DIVISION OF SPECIALIZED ANTI-EPIDEMIC FORMATION DURING OBJECT EXERCISE OF LOCALIZATION A CHOLERA IMPORTED FOCUS

The results of the object exercise of the Specialized Anti-Epidemic Formation (SAEF) of Irkutsk Antiplague Research Institute performed in July 2011 are summarized. According to the exercise plan, SAEF subdivisions carried out tasks on monitoring of surface waters in conditions of an imported, cholera focus. GIS (Geo-Informational Systems)-technologies and. GPS-navigation were used, for optimization, the SAEF actions. Algorithm of measures on the basis of the epidemic significance of vibrios isolated, from surface waters was developed

MULTILAYER STRUCTURES BASED ON PCM WITH TUNABLE REFLECTION AND TRANSMISSION CHARACTERISTICS FOR FULLY OPTICAL ROUTING DEVICES

The reported study was funded by RFBR according to the research project # 19-37-60023

Tactics for Specialized Anti-Epidemic Team (SAET) Deployment under the Conditions of Large-Scale High Water in the Far Eastern Territory. Communication 2. Peculiarities of Operational Activities of the Laboratory-Epidemiological SAET Reinforcement Unit Deployed in the Khabarovsk Territory and the Jewish Autonomous Region

Taking into consideration emergency conditions of rainfall flooding in the Khabarovsk Territory and the Jewish Autonomous Region in August-September 2013, forming premises for aggravation of the epidemiological situation a decision was made to deploy a laboratory-epidemiological SAET reinforcement unit No. 2 (SAET-2) from Irkutsk Research Anti-Plague Institute into the exposed area. SAET-2 staff was step-by-step relocated to the site of emergency to participate in the inspectional operations. Withdrawal of specialists was also performed on a stage-by-stage basis as the work advanced. For the first time ever SAET was established right at the natural disaster site and recruited from experts who are on regular SAET-2 staff of the Irkutsk Research Anti-Plague Institute, and from personnel reserve of the Rospotrebnadzor institutions in the Khabarovsk Territory. Complex approach, applied for the management of its work, allowed for alliance of forces and facilities of various Rospotrebnadzor territorial establishments, Rosselkhoznadzor and veterinary medicine institutions into the uniform mobile specialized brigade avoiding overlap of responsibilities and interference into day-to-day operational activities of Rospotrebnadzor territorial institutions. SAET-2 was to implement a complex of measures for sanitary-hygienic and epidemiological surveillance over the municipal territories suffered from flood. Team operational activities were carried out on the basis of stationary laboratories at the territorial establishments of Rospotrebnadzor in the Khabarovsk Territory and the Jewish Autonomous Region that were converted for working under emergency conditions mode. The mobile brigade has performed the tasks successfully. It has provided sanitary-epidemiological welfare of the population under emergency conditions of rainfall flood

First Observation of the Doubly Charmed Baryon Xi_cc^+

We observe a signal for the doubly charmed baryon Xi_cc^+ in the charged decay mode Xi_cc^+ --> Lambda_c^+ K- pi+ in data from SELEX, the charm hadro-production experiment at Fermilab. We observe an excess of 15.9 events over an expected background of 6.1 +/- 0.5 events, a statistical significance of 6.3sigma. The observed mass of this state is (3519 +/- 1) MeV/c^2. The Gaussian mass width of this state is 3MeV/c^2, consistent with resolution; its lifetime is less than 33fsec at 90% confidence.Comment: 5 pages, 3 figures, accepted for publication in Physical Review Letter