42 research outputs found
Data-Oriented Characterization of Application-Level Energy Optimization
Abstract. Empowering application programmers to make energy-aware decisions is a critical dimension of energy optimization for computer systems. In this paper, we study the energy impact of alternative data management choices by programmers, such as data access patterns, data precision choices, and data organization. Second, we attempt to build a bridge between application-level energy management and hardware-level energy management, by elucidating how various application-level data management features respond to Dynamic Voltage and Frequency Scal-ing (DVFS). Finally, we apply our findings to real-world applications, demonstrating their potential for guiding application-level energy opti-mization. The empirical study is particularly relevant in the Big Data era, where data-intensive applications are large energy consumers, and their energy efficiency is strongly correlated to how data are maintained and handled in programs
Predicting olfactory receptor neuron responses from odorant structure
Background Olfactory receptors work at the interface between the chemical world of volatile molecules and the perception of scent in the brain. Their main purpose is to translate chemical space into information that can be processed by neural circuits. Assuming that these receptors have evolved to cope with this task, the analysis of their coding strategy promises to yield valuable insight in how to encode chemical information in an efficient way. Results We mimicked olfactory coding by modeling responses of primary olfactory neurons to small molecules using a large set of physicochemical molecular descriptors and artificial neural networks. We then tested these models by recording in vivo receptor neuron responses to a new set of odorants and successfully predicted the responses of five out of seven receptor neurons. Correlation coefficients ranged from 0.66 to 0.85, demonstrating the applicability of our approach for the analysis of olfactory receptor activation data. The molecular descriptors that are best-suited for response prediction vary for different receptor neurons, implying that each receptor neuron detects a different aspect of chemical space. Finally, we demonstrate that receptor responses themselves can be used as descriptors in a predictive model of neuron activation. Conclusions The chemical meaning of molecular descriptors helps understand structure-response relationships for olfactory receptors and their 'receptive fields'. Moreover, it is possible to predict receptor neuron activation from chemical structure using machine-learning techniques, although this is still complicated by a lack of training data
Pembauran Budaya di Desa Rantau Sakti Kecamatan Tambusai Utara Kabupaten Rokan Hulu
This study is to research how the intercourse of culture that existed in the Rantau Sakti village Tambusai Utara District and Rokan Hulu Regent intertribal nasions of Java, Medan Java, Batak, Minang, and Melayu. Theres a launching factors and hindrance factors too in culture intercourse. The data tekhnic collection with the koesioner, interview, and documentation. And the analisys of data is descriptive where the data presented in the form of a diagrams, percentages, pictures, and explanations. The research results show that The lives of the multicultural that could lead to the occurrence of intercourse of culture through assimilation, acculturation, and amalgamation. The intercourse of culture through three aspects of it can run well theres happened in Rantau Sakti village on seven principles like language, system of knowledge , a social organization , celebration life and technologi, means of subsistence, religion, and art . There is also intercourse of culture with amalgamation culture that leads to assimilation and acculturation. Its launching factor are the attitude of tolerance and open, in common religion, and the same occasion in the economic field. While the hindrance factor are differences of religion and stereotype (ethnic prejudice). Those two factors each happened to the process of changing culture with assimilation, acculturation, and amalgamation That leads to a positive thing.Keyword: The Culture Intercourse, Inter-ethnic
Androgen receptor expression in male breast carcinoma: lack of clinicopathological association
Androgen receptor (AR) expression was retrospectively analysed in 47 primary male breast carcinomas (MBCs) using a monoclonal antibody on formalin-fixed, paraffin-embedded tissues. AR immunopositivity was detected in 16 out of 47 (34%) cases. No association was found with patient age, tumour stage, progesterone receptor (PGR) or p53 protein expression. Well-differentiated MBCs tended to be AR positive more often than poorly differentiated ones (P= 0.08). A negative association was found between ARs and cell proliferative activity: MIB-1 scores were higher (25.4%) in AR-negative than in AR-positive cases (21.11%; P= 0.04). A strong positive association (P= 0.0001) was found between ARs and oestrogen receptors (ERs). In univariate analysis, ARs (as well as ERs and PGRs) were not correlated with overall survival; tumour histological grade (P= 0.02), size (P= 0.01), p53 expression (P= 0.0008) and MIB-1 scores (P= 0.0003) had strong prognostic value. In multivariate survival analysis, only p53 expression (P= 0.002) and histological grade (P= 0.02) retained independent prognostic significance. In conclusion, the lack of association between AR and most clinicopathological features and survival, together with the absence of prognostic value for ER/PGR status, suggest that MBCs are biologically different from female breast carcinomas and make it questionable to use antihormonal therapy for patients with MBC. © 1999 Cancer Research Campaig
Bifunctional Heterostructure Assembly of NiFe LDH Nanosheets on NiCoP Nanowires for Highly Efficient and Stable Overall Water Splitting
3D hierarchical heterostructure NiFe LDH@NiCoP/NF electrodes are prepared successfully on nickel foam with special interface engineering and synergistic effects. This research finds that the asâprepared NiFe LDH@NiCoP/NF electrodes have a more sophisticated inner structure and intensive interface than a simple physical mixture. The NiFe LDH@NiCoP/NF electrodes require an overpotential as low as 120 and 220 mV to deliver 10 mA cmâ2 for hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) in 1 m KOH, respectively. Tafel and electrochemical impedance spectroscopy further reveal a favorable kinetic during electrolysis. Specifically, the NiFe LDH@NiCoP/NF electrodes are simultaneously used as cathode and anode for overall water splitting, which requires a cell voltage of 1.57 V at 10 mA cmâ2. Furthermore, the synergistic effect of the heterostructure improves the structural stability and promotes the generation of active phases during HER and OER, resulting in excellent stability over 100 h of continuous operation. Moreover, the strategy and interface engineering of the introduced heterostructure can also be used to prepare other bifunctional and costâefficient electrocatalysts for various applications
Microstructural Analysis of Local Silicon Corrosion of Bifacial Solar Cells as Root Cause of Potential-Induced Degradation at the Rear Side
Bifacial passivated emitter and rear cells (PERC+) can suffer from potentialâinduced degradation (PID) of the rear side. Rearâside PID tests of industrial solar cells lead to more than 12% power degradation that is not recoverable under illumination or dark storage. A microstructural rootâcause analysis of the rear side reveals localized spots with increased carrier recombination as the origin of the power losses. Morphology and defect distribution depend on the temperature (60 and 85â°C) applied for PID acceleration. Individual defects are analyzed at the atomic level, revealing a corrosion of the silicon bulk at the Si/AlOx interface. A laterally extending Na accumulation at the interface and an increased concentration of further impurities are observed together with large stacking fault defects. The formation of the defects will be discussed within a simple model for a cathodic corrosion of Si and the impact of interfacial contaminations during solar cell processing
Root cause analysis on corrosive potential-induced degradation effects at the rear side of bifacial silicon PERC solar cells
Potential induced degradation (PID) of solar cells can severely reduce a PV module's performance. In case of bifacial solar cells, the rear side is another source of PID as was found for industrially produced bifacial PERC solar cells from three different manufacturers. It is shown that a rear-side PID test can lead to more than 12% power degradation. The observed PID mechanisms are not completely recoverable implying long-term losses under field operation. This new, non-recoverable PID effects are characterized by a locally increased recombination at the rear side of the cells. From nano-scale analytics by means of transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM) and energy-dispersive X-ray spectroscopy (EDXS) are performed and PID related defects are traced back to a local Si corrosion and delamination of the passivation layers. At the Si passivation interface an increased amount of SiOx, Na and further impurities are found that indicate an electrochemically driven corrosion process under cathodic conditions