526 research outputs found
How psychological dispositions influence the theology of the afterlife
Humans across cultures have formulated rich views about what happens after death,
including reincarnationist beliefs and beliefs in an afterlife. Theologians further
develop and elaborate these views. Recent work in the cognitive science of religion
suggests that afterlife beliefs are caused by psychological dispositions that are a stable
part of human cognition. For instance, humans intuitively conceptualize themselves
and others as composed of material and nonmaterial parts, which facilitates the idea
that physical death is not the end of personhood. In this paper, we explore how
psychological dispositions influence theological views of the afterlife, focusing on
Mormon theology
How do philosophers evaluate natural theological arguments? : an experimental philosophical investigation
Emotional responses to fiction: an evolutionary perspective
Across cultures, humans create fictional worlds. Storytelling is a cross-cultural phenomenon, taking various forms, such as narrative dances that act out passages of the Ramayana and Mahabharata, Latin American telenovelas, recitations by West African griots (troubadours) accompanied by a kora (twenty-one-string lute), and intricate Russian novels. Narratives elicit emotions. Many authors have proposed comprehensive theories about what emotions are, and how they could be categorized. Darwin (1872) was the first to propose an evolutionary, functional explanation for emotions: they help to prepare an animal for appropriate actions and to effectively communicate inner states, such as distress or anger, to others. Emotions elicited by fiction, and by art more broadly, do not fit neatly in these evolutionary scenarios. To understand the role of emotions in fiction, it is important to look at the motivations of both authors and consumers. Social novels highlight problematic social circumstances, such as extreme poverty, slavery, or animal cruelty
A mathematical model for the development of mealiness in apples
Mealiness in apples (Malus domestica Borkh.) is an internal quality defect which is characterised by a dry and crumbly texture. It is related to the relative strength of the cell wall and the middle lamella. A mathematical model has been built to relate changes in the texture attributes juiciness, tensile strength and hardness, which are associated with mealiness, to the development of the turgor pressure of the tissue and the degree of hydrolysis of the middle lamella. The latter, in turn, are described in terms of properties which are meaningful from the physiological point of view, such as starch content, soluble solids content, non-hydrolysed and hydrolysed middle lamella, water in the symplast, and water in the apoplast. Biochemical reactions as well as water transfer processes are incorporated in the model. The parameter values of the model are estimated using experimental data from a storage experiment. The model fits the three texture characteristics adequately. The correlation coefficients between the parameters were below 0.96, which indicates that the model does not overfit the data
Study of cavernous underground conduits in Nam La (Northwest Vietnam) by an integrative approach
This paper presents the result of an investigation of underground conduits, which connect the swallow holes and the resurgence of a blind river in the tropical, highly karstified limestone Nam La catchment in the NW of Vietnam. The Nam La River disappears underground in several swallow holes near the outlet of the catchment. In the rainy season this results in flooding upstream of the sinkholes. A hypothesis is that the Nam La River resurges at a large cavern spring 4.5 km east of the catchment outlet. A multi-thematic study of the possible connections between the swallow holes and the resurgence was carried out to investigate the geological structure, tectonics, cave structure analysis and discharge time series. The existence of the underground conduits was also tested and proven by tracer experiments. On the basis of a lineament analysis the location of the underground conduits were predicted. A remote sensing derived lineament-length density map was used to track routes from the swallow holes to the resurgence, having the shortest length but highest lineament density. This resulted in a plan-view prediction of underground conduits that matches with the cave and fault development. The functioning of the conduits was further explained by analysing flooding records of a nearby doline, which turns out to act as a temporary storage reservoir mitigating flooding of the catchment outlet area
Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor
The anti-apoptotic Bcl-2 protein is the founding member and namesake of the Bcl-2-protein family. It has recently been demonstrated that Bcl-2, apart from its anti-apoptotic role at mitochondrial membranes, can also directly interact with the inositol 1,4,5-trisphosphate receptor (IP3R), the primary Ca2+-release channel in the endoplasmic reticulum (ER). Bcl-2 can thereby reduce pro-apoptotic IP3R-mediated Ca2+ release from the ER. Moreover, the Bcl-2 homology domain 4 (Bcl-2-BH4) has been identified as essential and sufficient for this IP3R-mediated anti-apoptotic activity. In the present study, we investigated whether the reported inhibitory effect of a Bcl-2-BH4 peptide on the IP (3)R1 was related to the distinctive alpha-helical conformation of the BH4 domain peptide. We therefore designed a peptide with two glycine "hinges" replacing residues I14 and V15, of the wild-type Bcl-2-BH4 domain (Bcl-2-BH4-IV/GG). By comparing the structural and functional properties of the Bcl-2-BH4-IV/GG peptide with its native counterpart, we found that the variant contained reduced alpha-helicity, neither bound nor inhibited the IP (3)R1 channel, and in turn lost its anti-apoptotic effect. Similar results were obtained with other substitutions in Bcl-2-BH4 that destabilized the alpha-helix with concomitant loss of IP3R inhibition. These results provide new insights for the further development of Bcl-2-BH4-derived peptides as specific inhibitors of the IP3R with significant pharmacological implications
Comparison between sensorial and instrumental measurements for mealiness assessment in apples
Definition and establishment of assessment procedures for mealiness of apple fruits using sensory and instrumental measurements were performed on ‘Boskoop', ‘Cox's Orange Pippin’ and ‘Jonagold’ samples with varying degrees of mealiness. The sensory procedure profiled mealiness as a loss of crispness, hardness, and juiciness, with an increase in the floury sensation in the mouth. High correlations between the sensory descriptors and instrumental parameters was shown through principal component analysis. The instrumental procedures (confined compression of fruit cylinders and acoustic impulse response) gave coefficients of determination for juiciness and crispness of 0.85 and 0.71, respectively. This level of accuracy indicates the possibility of establishin
Normal transport properties for a classical particle coupled to a non-Ohmic bath
We study the Hamiltonian motion of an ensemble of unconfined classical
particles driven by an external field F through a translationally-invariant,
thermal array of monochromatic Einstein oscillators. The system does not
sustain a stationary state, because the oscillators cannot effectively absorb
the energy of high speed particles. We nonetheless show that the system has at
all positive temperatures a well-defined low-field mobility over macroscopic
time scales of order exp(-c/F). The mobility is independent of F at low fields,
and related to the zero-field diffusion constant D through the Einstein
relation. The system therefore exhibits normal transport even though the bath
obviously has a discrete frequency spectrum (it is simply monochromatic) and is
therefore highly non-Ohmic. Such features are usually associated with anomalous
transport properties
Global observations of tropospheric BrO columns using GOME-2 satellite data
Measurements from the GOME-2 satellite instrument have been analyzed for tropospheric BrO using a residual technique that combines measured BrO columns and estimates of the stratospheric BrO content from a climatological approach driven by O<sub>3</sub> and NO<sub>2</sub> observations. Comparisons between the GOME-2 results and BrO vertical columns derived from correlative ground-based and SCIAMACHY nadir observations, present a good level of consistency. We show that the adopted technique enables separation of stratospheric and tropospheric fractions of the measured total BrO columns and allows quantitative study of the BrO plumes in polar regions. While some satellite observed plumes of enhanced BrO can be explained by stratospheric descending air, we show that most BrO hotspots are of tropospheric origin, although they are often associated to regions with low tropopause heights as well. Elaborating on simulations using the <i>p</i>-TOMCAT tropospheric chemical transport model, this result is found to be consistent with the mechanism of bromine release through sea salt aerosols production during blowing snow events. No definitive conclusion can be drawn however on the importance of blowing snow sources in comparison to other bromine release mechanisms. Outside polar regions, evidence is provided for a global tropospheric BrO background with column of 1–3 &times; 10<sup>13</sup> molec cm<sup>&minus;2</sup>, consistent with previous estimates
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