1,083 research outputs found
Factores que afectan la digestibilidad, valor nutritivo y energético del banano para ratas y cerdos
Es costumbre muy generalizada emplear los granos como fuentes de energ1a en raciones para cerdos. De estos cereales sin lugar a dudas, el maíz ocupa el primer lugar en utilizaci6n. Si consideramos su alto precio por tonelada y la gran demanda para consumo humano, surge la necesidad inmediata de buscar otras fuentes energéticas que permitan la substituci6n total o parcial, manteniendo al mismo tiempo buenos rendimientos y contribuyendo a disminuir el costo de producci6n por kilogramo de carne. Las áreas bananeras de las zonas tropicales ofrecen buenas perspectivas y posibilidades para alcanzar éste objetivo.Banano- Musa acuminata - Musa paradisiacaMaestría en CienciasMaestrí
Electron beam induced electronic transport in alkyl amine-intercalated VOx nanotubes
The electron beam induced electronic transport in primary alkyl amine-intercalated V2O5 nanotubes is investigated where the organic amine molecules are employed as molecular conductive wires to an aminosilanized substrate surface and contacted to Au interdigitated electrode contacts. The results demonstrate that the high conductivity of the nanotubes is related to the non-resonant tunnelling through the amine molecules and a reduced polaron hopping conduction through the vanadium oxide itself. Both nanotube networks and individual nanotubes exhibit similarly high conductivities where the minority carrier transport is bias dependent and nanotube diameter invariant
Scalar Field Dark Matter: behavior around black holes
We present the numerical evolution of a massive test scalar fields around a
Schwarzschild space-time. We proceed by using hyperboloidal slices that
approach future null infinity, which is the boundary of scalar fields, and also
demand the slices to penetrate the event horizon of the black hole. This
approach allows the scalar field to be accreted by the black hole and to escape
toward future null infinity. We track the evolution of the energy density of
the scalar field, which determines the rate at which the scalar field is being
diluted. We find polynomial decay of the energy density of the scalar field,
and use it to estimate the rate of dilution of the field in time. Our findings
imply that the energy density of the scalar field decreases even five orders of
magnitude in time scales smaller than a year. This implies that if a
supermassive black hole is the Schwarzschild solution, then scalar field dark
matter would be diluted extremely fastComment: 15 pages, 21 eps figures. Appendix added, accepted for publication in
JCA
Reliable resolution of ambiguous hepatitis C virus genotype 1 results with the Abbott HCV Genotype Plus RUO assay
Hepatitis C; Genotype; Abbott HCVHepatitis C; Genotip; Abbott HCVHepatitis C; Genotipo; Abbott HCVAccurate subtyping of hepatitis C virus genotype 1 (HCV-1) remains clinically and epidemiologically relevant. The Abbott HCV Genotype Plus RUO (GT Plus) assay, targeting the core region, was evaluated as a reflex test to resolve ambiguous HCV-1 results in a challenging sample collection. 198 HCV-1 specimens were analysed with GT Plus (38 specimens with and 160 without subtype assigned by the Abbott RealTime Genotype II (GT II) assay targeting the 5'NC and NS5B regions). Sanger sequencing of the core and/or NS5B regions were performed in 127 specimens without subtype assignment by GT II, with "not detected" results by GT Plus, or with mixed genotypes/subtypes. The remaining GT Plus results were compared to LiPA 2.0 (n = 45) or just to GT II results if concordant (n = 26). GT Plus successfully assigned the subtype in 142/160 (88.8%) samples. "Not detected" results indicated other HCV-1 subtypes/genotypes or mismatches in the core region in subtype 1b. The subtyping concordance between GT Plus and either sequencing or LiPA was 98.6% (140/142). Therefore, combined use of GT II and GT Plus assays represents a reliable and simple approach which considerably reduced the number of ambiguous HCV-1 results and enabled a successful subtyping of 98.9% of all HCV-1 samples
Characterisation of the fouling of an ultrafiltration polyethersulfone membrane fouled by an emulsion modelling lipids issued from Microalgae
International audienc
Structural and functional properties of region II-plus of the malaria circumsporozoite protein.
Novel insights into the cardio-protective effects of FGF21 in lean and obese rat hearts
Aims: Fibroblast growth factor 21 (FGF21) is a hepatic metabolic regulator with pleotropic actions. Its plasma concentrations are increased in obesity and diabetes; states associated with an increased incidence of cardiovascular disease. We therefore investigated the direct effect of FGF21 on cardio-protection in obese and lean hearts in response to ischemia.
Methods and Results: FGF21, FGF21-receptor 1 (FGFR1) and beta-Klotho (βKlotho) were expressed in rodent, human hearts and primary rat cardiomyocytes. Cardiac FGF21 was expressed and secreted (real time RT-PCR/western blot and ELISA) in an autocrine-paracrine manner, in response to obesity and hypoxia, involving FGFR1-βKlotho components. Cardiac-FGF21 expression and secretion were increased in response to global ischemia. In contrast βKlotho was reduced in obese hearts. In isolated adult rat cardiomyocytes, FGF21 activated PI3K/Akt (phosphatidylinositol 3-kinase/Akt), ERK1/2(extracellular signal-regulated kinase) and AMPK (AMP-activated protein kinase) pathways. In Langendorff perfused rat [adult male wild-type wistar] hearts, FGF21 administration induced significant cardio-protection and restoration of function following global ischemia. Inhibition of PI3K/Akt, AMPK, ERK1/2 and ROR-α (retinoic-acid receptor alpha) pathway led to significant decrease of FGF21 induced cardio-protection and restoration of cardiac function in response to global ischemia. More importantly, this cardio-protective response induced by FGF21 was reduced in obesity, although the cardiac expression profiles and circulating FGF21 levels were increased.
Conclusion: In an ex vivo Langendorff system, we show that FGF21 induced cardiac protection and restoration of cardiac function involving autocrine-paracrine pathways, with reduced effect in obesity. Collectively, our findings provide novel insights into FGF21-induced cardiac effects in obesity and ischemia
Lipofibromatous hamartoma of the median nerve
Lipofibromatous hamartoma is a rare tumour of peripheral nerves which is characterised by an excessive infiltration of the epineurium and perineurium by fibroadipose tissue. To the best of our knowledge, only approximately 88 cases are reported in the literature. We report a rare case of lipofibromatous hamartoma of the median nerve causing secondary carpal tunnel syndrome in a 25 year old patient. This patient was treated conservatively with decompression and biopsy and experienced a complete resolution of symptoms post-operatively. Magnetic resonance imaging may be used to diagnose this lesion as it has very distinctive characteristics. Multiple conditions have been associated with this lesion and a greater understanding of these associations may clarify the pathogenesis. The architecture of the tumour makes excision very challenging and the surgical management remains controversial. A review of the literature regarding the etiology, pathogenesis and surgical management of lipofibromatous hamartoma is included
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