Single-Spin Asymmetries for Small-Angle Pion Production in High-Energy Hadron Collisions

Within the framework of a simple model, we study single-spin asymmetries for pion production in hadron-hadron collisions at high-energies with one hadron polarised. The asymmetries are generated via a mechanism of final (initial) state interactions. For peripheral kinematics, when the pion belongs to the fragmentation region of the polarised proton, we find non-zero asymmetries in the high-energy limit. Numerical results and comparision with existing experimental data are presented. We also discuss the relationship with odderon exchange phenomenology.Comment: LaTeX2e, 12 pages, 4 figure files (2 TeX and 2 eps), uses axodraw, and cite packages; submitted to Eur. Phys. J

The elicitation of key performance indicators of e-government providers: A bottom-up approach

Copyright @ 2013 EMCIS.Delivering an adequate e-Government service (e-service) is becoming more of a necessity in today's digital world. In order to improve e-services and increase the engagement of both users' and providers' side, studies on the performance evaluation of such provided e-services are taking places. However a clear identification of the key performance indicators from the e-Government providers’ side is not well explored. This shortcoming hampers the conduct of a holistic evaluation of an e-service provision from the perspective of its stakeholders in order to improve e-services as well as to increase e-services take-ups. In this paper, a systematic process to identify indicators is implemented based on a bottom-up approach. The process used three focus-group meetings with providers, users, and academics in Qatar, Lebanon and UK to collect, identify and validate key indicators from the perspective of e-services’ providers. The approach resulted in the identification of five factors levels (service, technology, employees, policy and management and social responsibilities) with fifteen sub-categories of SMART variables. Hence, leading to the development of a new model, STEPS, that can fully explain and predict e-government success from the providers’ point of view. It will work as a strategic management tool to align various stakeholders on common goal and values based on evidence based evaluation of e-services using smart measurable indicators for the improvement of an e-service at the engagement level in the field of e-government. In addition, other fields can benefit from the outcome of this work, such as logistics service providers, who make their services available across new and existing relationships between the Internet commerce firms, their customers, and their vendors

Note on flat foliations of spherically symmetric spacetimes

It is known that spherically symmetric spacetimes admit flat spacelike foliations. We point out a simple method of seeing this result via the Hamiltonian constraints of general relativity. The method yields explicit formulas for the extrinsic curvatures of the slicings.Comment: 4 pages, to appear in PRD, reference added, typos correcte

Clinical study of Rh-isoimmunization in pregnant women

Background: Iso-immunization has been defined as the process whereby immune antibodies are produced in an individual in response to antigens from another individual of same species. Objective was to study the fetal outcome in immunized and non-immunized women and also to prevent isoimmunization during pregnancy and labour.Methods: A total of 40 patients attending outdoor antenatal clinic or admitted in the indoor wards in obstetric unit of Obstetrics and Gynecology department were included in the present study which was hospital based cross sectional study. The study was carried out for one year at Government Medical College Jagdalpur, Chhattisgarh, India. Permission from Institutional Ethics Committee was obtained. From each and every patient included in the study, initially informed individual consent was taken.Results: Maximum patients (25%) had an income of Rs. 200- 300 per month and minimum patients (10%) had an income of Rs. 500- 600 per month. Maximum cases of Rh – negative patients 87.5% are Hindus and 10 % are Muslims while only 2.5% are Christians. The percentage of patients below 20 years is 2.5, that between 20 to 25 are 67.5, between 26 to 30 is 27.5 and between 31 to 35 is 2.5. Thus, maximum patients belong to the age group 20 to 25 years and above 31 years.. Accordingly, 6 patients had history of abortion, 2 had pre- term deliveries, and 18 had full term deliveries. 4 had history of operation and 1 had history of jaundice in previous children. Cases with presence of Rh- Antibody in Maternal Circulation during Pregnancy. It was found that one out of 40 patients, had Rh- Antibody in titer of 1: 128 and 39 cases, did not show presence of Rh- Antibody in their circulation. Outcome of pregnancy in 40 patients studied. 3 patients had pre- mature labour, 26 had normal vaginal delivery, 10 had caesarean section and one patient was Ante- natal.Conclusions: Present study reveals more than Maximum patients were from low socioeconomic group and minimum cases were from higher socio- economic group. Majority of cases were Hindus, next in order Muslims and then Christians. Age of maximum patients ranged from 20-25 years. Maximum patients had normal full term deliveries. In 65% cases, outcome of pregnancy was normal vaginal delivery

Prevalence of human respiratory syncytial virus circulating in Iran

Respiratory syncytial virus (RSV) is a leading cause of acute respiratory infection during early childhood and is associated with a great burden on patients, parents, and society. While no treatment is yet available, results from recent phase 2 clinical trials of cell-entry inhibitors and RSV vaccines are promising. To prepare for introduction of these novel therapeutics, good understanding of its molecular epidemiology and continuous RSV surveillance data are necessary. This paper provides an overview of RSV prevalence and genotype distribution in Iran from 1996 to 2013. This meta-analysis includes 21 published studies. In total, 775 (18.7) of 4140 respiratory specimens were positive for RSV infection. The male-female ratio of RSV-positive patients was 1.5:1. Significant peaks of RSV infection were detected during the cold season (November-March). RSV infection was mainly observed in patients <2 years of age. Phylogenetic studies showed that genotypes GA1, GA2, GA5, and BA co-circulated in Iran in 2007-2013. This review highlights the necessity of introducing standard molecular surveillance programs to inform the epidemiological, clinical, and pathological characteristics of various RSV genotypes. Improved understanding of the molecular epidemiology will be useful for development of novel RSV therapeutics. © 2015 King Saud Bin Abdulaziz University for Health Sciences

The ubiquitin receptor S5a/Rpn10 links centrosomal proteasomes with dendrite development in the mammalian brain

SummaryProteasomes drive the selective degradation of protein substrates with covalently linked ubiquitin chains in eukaryotes. Although proteasomes are distributed throughout the cell, specific biological functions of the proteasome in distinct subcellular locales remain largely unknown. We report that proteasomes localized at the centrosome regulate the degradation of local ubiquitin conjugates in mammalian neurons. We find that the proteasomal subunit S5a/Rpn10, a ubiquitin receptor that selects substrates for degradation, is essential for proteasomal activity at centrosomes in neurons and thereby promotes the elaboration of dendrite arbors in the rodent brain in vivo. We also find that the helix-loop-helix protein Id1 disrupts the interaction of S5a/Rpn10 with the proteasomal lid and thereby inhibits centrosomal proteasome activity and dendrite elaboration in neurons. Together, our findings define a function for a specific pool of proteasomes at the neuronal centrosome and identify a biological function for S5a/Rpn10 in the mammalian brain

Chemoresistance of Lung Cancer Cells: 2D and 3D In Vitro Models for Anticancer Drug Screening

Chemoresistance of lung cancer cells is a key factor that limits the treatment of lung cancer patients. Patients may initially respond to standard chemotherapy, but this is often followed by rapid development of drug resistance and disease progression. Tumor heterogeneity and the presence of putative cancer stem-like cells (CS-LCs) provide a viable explanation for the chemoresistance of several types of tumors. In this book chapter, we will first describe the current knowledge of the role of both tumor heterogeneity and CS-LCs in lung cancer chemoresistance, tumor progression and metastasis. Next, we will discuss ongoing strategies at the in vitro level to screen for more effective anticancer drugs. We will specifically focus in three-dimensional (3D) culture systems (Spheroids and tumorspheres) and their application in anticancer drug discovery for lung cancer

What determines the yen swap spread?

We investigate if Japanese yen denominated interest rate swap spreads price risks in addition to liquidity and default risk. These additional risks include: the time-varying correlation between interest rates of different types and maturities; business cycle risk; and market skewness risk. Our analysis, over a number of different maturities and sample periods, supports the existence of an additional risk premium. We also show that the time-varying correlation between short term market interest rates (e.g., TIBOR) and the longer term Government bond yield (e.g., Gensaki) is of particular importance. Japanese yen swap spreads are shown to contain both pro-cyclical and counter-cyclical elements of business cycle risk, positive risk premia for skewness risk and variable risk premia for correlation risk (between fixed and floating interest rates)

Near threshold radiative 3π\pi production in e+e−e^+e^- annihilation

We consider the $\pi^+\pi^-\pi_0\gamma$ final state in electron-positron annihilation at cms energies not far from the threshold. Both initial and final state radiations of the hard photon is considered but without interference between them. The amplitude for the final state radiation is obtained by using the effective Wess-Zumino-Witten Lagrangian for pion-photon interactions valid for low energies. In real experiments energies are never such small that $\rho$ and $\omega$ mesons would have negligible effect. So a phenomenological Breit-Wigner factor is introduced in the final state radiation amplitude to account for the vector mesons influence. Using radiative 3$\pi$ production amplitudes, a Monte Carlo event generator was developed which could be useful in experimental studies.Comment: 15 pages, Latex, 6 figures. Misprints corrected. Version to be published in JHE