512 research outputs found

    Consumer Willingness to Pay and Marketing Opportunities for "Quality Guaranteed Tree-Ripened Peaches" in New York State

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    This study identifies consumer characteristics associated with willingness to pay a higher price for quality guaranteed tree-ripened peaches, with a focus on evaluating factors important to consumers when making decisions to purchase tree-ripened peaches. Telephone interviews were conducted with consumers in New York State in summer, 2002. Seventy-eight percent of the 258 survey respondents reported that they were willing to pay a higher price. A logistical regression model of willingness to pay was estimated. The empirical results indicated that willingness to pay was positively affected by the existence of previous experiences in purchasing tree-ripened peaches and by consumer dissatisfaction with peaches consumed in the past. An analysis of consumer experiences and consumer dissatisfaction showed that consumers in the two identified segments had mutually exclusive characteristics that present marketing opportunities for high quality New York-grown peaches.Consumer/Household Economics,

    Market Opportunities for New Sauerkraut Products

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    Food Consumption/Nutrition/Food Safety, Marketing,

    Ultrasonic propagation in gases at high temperatures

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    Ultrasonic pulse method /1 to 3 MHz/ measures both sound speed and absorption in monatomic and polyatomic gases in a temperature range of 300 to 20000 degrees K at atmospheric pressure. Helium, nitrogen, oxygen, and argon are investigated

    RISK ANALYSIS OF ADOPTING ZERO RUNOFF SUBIRRIGATION SYSTEMS IN GREENHOUSE OPERATIONS: A MONTE CARLO SIMULATION APPROACH

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    Zero runoff subirrigation (ZRS) technology can effectively manage fertilizer input while improving greenhouse production efficiency. However, high capital investment costs and inadequate technical information to growers are impediments for adoption. A Monte Carlo simulation was used to compare the profitability and risks of alternative ZRS system investments for greenhouse operations in the northeastern and north central United States. Results showed that the Dutch movable tray system and the flood floor system were most profitable and least risky for small potted plant and bedding crop flat production, respectively. The trough bench system was least favorable because its profitability was low and highly volatile.Risk and Uncertainty,

    Consumer Preferences and Marketing Opportunities for Premium “Tree-Ripened Peaches” in New York State

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    R.B. 2004-10Fruit growers in New York State are adding alternative fruit crops to their production acreage in an effort to diversify their apple orchards. Peach (Prunus persica L.) is a major crop used for that purpose because of the collaboration between growers and the Cornell Agricultural Experiment Station to develop new varieties that possess higher eating quality and more eye-appealing characteristics for the consumer market and because they are suitable for the growing environment in New York State. The goal of this study is to explore consumer interests in New York-grown premium tree-ripened peaches and develop strategic marketing recommendations on how the New York stone fruit industry can expand markets for these peaches. This research is divided into two parts: a qualitative study (focus group discussion) and a quantitative study (consumer phone survey). The purpose of the focus groups was to obtain in depth responses from consumers on their attitudes and purchase behaviors for fruit, peaches and New York-grown premium tree-ripened peaches. The consumer phone survey was designed to verify results from the focus group discussion among the general population and to determine consumers’ interests and willingness to pay a higher price for “quality-guaranteed premium treeripened peaches.” The focus groups and consumer phone surveys show that consumers, especially frequent fruit shoppers, are generally very interested in good quality peaches as well as “quality-guaranteed premium tree-ripened peaches”. Although it is usually recognized that good quality tree-ripened peaches are available at farm stands or farmers’ markets, they appear to be less available in the supermarkets where respondents in this study typically shop. This presents an opportunity for New York stone fruit growers to supply good and consistent quality fresh peaches through the supermarket channel. Peaches are prized for their juiciness, sweetness, and good flavor. However, consumers are frustrated by the difficulty they perceive in selecting peaches at the proper ripening stage to get the qualities they like. Quality and consistency of the product are key factors for consumer satisfaction, and a high level of satisfaction, in turn, increases consumer demand and repeat purchases for fresh peaches. If quality and consistency exist, consumers seem to be willing to pay higher prices and buy fewer peaches in order to get the product they like. Most consumers in this study recognized New York State as a region where peaches are grown and referred to these peaches as “local” or “homegrown.” Awareness of these shoppers about peaches grown in New York and their “local” nature clearly constitutes an advantage to build on when marketing New York-grown peaches. However, there are challenges when designing a marketing program to receive a premium price for high quality New York-grown tree-ripened peaches. Many consumers could not correctly identify tree-ripened peaches, and some expected a lower price for locally grown products. Moreover, some focus group participants viewed California peaches as larger and Pennsylvania peaches as more flavorful and predictable than New York peaches. iii Therefore, when promoting “quality-guaranteed New York-grown premium tree-ripened peaches” through the supermarkets channel, a good position statement, innovative packaging, and clear labeling at the point of purchase will be the major means of informing and influencing a potential buyer. It should emphasize high quality and be used as boldly and as creatively as possible to justify the higher price and stimulate sales for the “New York-grown qualityguaranteed premium tree-ripened peaches”. Moreover, given the narrow marketing window when fresh New York peaches are available and the excitement the arrival of the peach season appears to generate, both run-of-the-crop and premium varieties can benefit from intensive promotion of their arrival. Results from this study show that demographic factors generally do not affect consumer behavior in terms of purchasing peaches or tree-ripened peaches. Therefore, promotional programs targeting specific consumer groups are not necessary. Generating consumer satisfaction through good and consistent quality products is the key to successfully marketing “New York-grown quality-guaranteed premium tree-ripened peaches.

    An Evaluation of Therapeutic Noninferiority of 0.005% Latanoprost Ophthalmic Solution and Xalatan in Patients With Glaucoma or Ocular Hypertension.

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    PURPOSE: To assess the therapeutic noninferiority of 0.005% latanoprost ophthalmic solution versus Xalatan in the treatment of patients with primary open-angle glaucoma or ocular hypertension. PATIENTS AND METHODS: This was a double-masked, randomized, multicenter study. A total of 184 patients with a diagnosis of unilateral or bilateral primary open-angle glaucoma or ocular hypertension were randomly assigned to either 0.005% latanoprost ophthalmic solution or Xalatan for 12 weeks. The primary end-point was the change in intraocular pressure (IOP) at 12 weeks in the 2 groups. Noninferiority was reached if the 2-sided 95% confidence intervals (CI) for the difference between adjusted treatment means were entirely within the interval from -1.5 to +1.5 mm Hg. RESULTS: The difference between treatments in the change of IOP from baseline to the end of treatment was 0.12 mm Hg (95% CI: -0.47, 0.71) in the intention-to-treat population and 0 mm Hg (95% CI: -0.58, 0.57) in the per protocol population. There was no statistically significant difference between the 2 groups in terms of drug-related adverse events. The most commonly reported drug-related local adverse events were: ocular hyperemia, eyelashes growth, and eye irritation. CONCLUSIONS: This study demonstrates that 0.005% latanoprost ophthalmic solution is noninferior to Xalatan in lowering IOP and is generally well tolerate

    Clinical phenotypes of Parkinson’s disease associate with distinct gut microbiota and metabolome enterotypes

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    Parkinson’s disease (PD) is a clinically heterogenic disorder characterized by distinct clinical entities. Most studies on motor deficits dichotomize PD into tremor dominant (TD) or non-tremor dominant (non-TD) with akinetic-rigid features (AR). Different pathophysiological mechanisms may affect the onset of motor manifestations. Recent studies have suggested that gut microbes may be involved in PD pathogenesis. The aim of this study was to investigate the gut microbiota and metabolome composition in PD patients in relation to TD and non-TD phenotypes. In order to address this issue, gut microbiota and the metabolome structure of PD patients were determined from faecal samples using 16S next generation sequencing and gas chromatography–mass spectrometry approaches. The results showed a reduction in the relative abundance of Lachnospiraceae, Blautia, Coprococcus, Lachnospira, and an increase in Enterobacteriaceae, Escherichia and Serratia linked to non-TD subtypes. Moreover, the levels of important molecules (i.e., nicotinic acid, cadaverine, glucuronic acid) were altered in relation to the severity of phenotype. We hypothesize that the microbiota/metabolome enterotypes associated to non-TD subtypes may favor the development of gut inflammatory environment and gastrointestinal dysfunctions and therefore a more severe α-synucleinopathy. This study adds important information to PD pathogenesis and emphasizes the potential pathophysiological link between gut microbiota/metabolites and PD motor subtypes

    Long-term Exposure to Ambient Air Pollution and its Association with Mental Well-Being, Depression and Anxiety: A Nationally Representative Study

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    "Introduction: Exposure to ambient air pollution may play a role in the onset of common mental disorders like depressive and anxiety disorders. The association of long-term exposure to particles smaller than 10 μm (PM10) with these diseases remains unclear. This study aimed to estimate the association of long-term exposure to PM10 with mental well-being and the frequency of probable diagnosis of common mental disorders. Methods: A nationally representative cross-sectional study was done in mainland Portugal. Long-term exposure was estimated through one-year average concentrations of PM10, calculated with data from the Portuguese Environment Agency, attributed individually considering individuals’ postal codes of residence. The mental well-being and the probable diagnosis of common mental disorders were ascertained through the five-item Mental Health Inventory scale. Linear and Robust Poisson regression models were computed to estimate change percentages, prevalence ratios (PR), and their 95% confidence intervals (95% CI). Results: The median (interquartile range) concentration of PM10 was 18.6 (15.3 - 19.3) μg/m3. The mental well-being score was 72 (56 - 84) points, on a scale from 0 to 100. A probable diagnosis of common mental disorders was found in 22.7% (95% CI: 20.0 to 25.6). Long-term exposure to PM10 was associated with a non-statistically significant decrease in the mental well-being score [for each 10 μg/m³ increment in one-year average PM10 concentrations, there was a 2% (95% CI: -8 to 4) decrease], and with a non-statistically significant increase in the common mental health frequency (PR = 1.012, 95% CI: 0.979 to 1.045). Conclusion: We did not find statistically significant associations between long-term exposure to PM10 and mental well-being or the frequency of probable diagnosis of common mental disorders. These results may be explained by the reduced variability in the exposure values, given the geographical distribution and functioning of the network of air quality monitoring stations. This study contributes with evidence for low levels of air pollutants, being one of the first to adjust for individual and aggregate-level variables. Moreover, to the best of our knowledge, this was the first nationally representative, population-based study conducted on the Portuguese population using real-life data. Maintaining a robust and nationwide air quality monitoring network is essential for obtaining quality exposure data."he Portuguese National Health Examination Survey was developed as part of a project financed under the Public Health Initiatives Programme (“Improvement of epidemiological health information to support public health decision and management in Portugal. Towards reduced inequalities, improved health and bilateral cooperation”) with a €1 500 000 grant from Iceland, Liechtenstein and Norway, the EEA Grants and the Portuguese Government. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sec-tors

    FOXP3 expression in tumor cells and its role in cancer progression

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    Deep insight on FOXP3 expression in tumor cells and its role in cancer progression
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