5 research outputs found
Occurrence of antimicrobial resistance among bacterial pathogens and indicator bacteria in pigs in different European countries from year 2002 – 2004 : the ARBAO-II study
Background: The project "Antibiotic resistance in bacteria of animal origin – II" (ARBAO-II) was
funded by the European Union (FAIR5-QLK2-2002-01146) for the period 2003–05. The aim of this
project was to establish a program for the continuous monitoring of antimicrobial susceptibility of
pathogenic and indicator bacteria from food animals using validated and harmonised
methodologies. In this report the first data on the occurrence of antimicrobial resistance among
bacteria causing infections in pigs are reported.
Methods: Susceptibility data from 17,642 isolates of pathogens and indicator bacteria including
Actinobacillus pleuropneumoniae, Streptococcus suis and Escherichia coli isolated from pigs were
collected from fifteen European countries in 2002–2004.Results: Data for A. pleuropneumoniae from infected pigs were submitted from five countries. Most
of the isolates from Denmark were susceptible to all drugs tested with the exceptions of a low
frequency of resistance to tetracycline and trimethoprim – sulphonamide.
Data for S. suis were obtained from six countries. In general, a high level of resistance to
tetracycline (48.0 – 92.0%) and erythromycin (29.1 – 75.0%) was observed in all countries whereas
the level of resistance to ciprofloxacin and penicillin differed between the reporting countries.
Isolates from England (and Wales), France and The Netherlands were all susceptible to penicillin.
In contrast the proportion of strains resistant to ciprofloxacin ranged from 12.6 to 79.0% (2004)
and to penicillin from 8.1 – 13.0% (2004) in Poland and Portugal.
Data for E. coli from infected and healthy pigs were obtained from eleven countries. The data reveal
a high level of resistance to tetracyclines, streptomycin and ampicillin among infected pigs whereas
in healthy pigs the frequency of resistance was lower.
Conclusion: Bacterial resistance to some antimicrobials was frequent with different levels of
resistance being observed to several antimicrobial agents in different countries. The occurrence of
resistance varied distinctly between isolates from healthy and diseased pigs, with the isolates from
healthy pigs generally showing a lower level of resistance than those from diseased pigs.
The study suggests that the choice of antimicrobials used for the treatment of diseased animals
should preferably be based on knowledge of the local pattern of resistance
Occurrence of antimicrobial resistance among bacterial pathogens
Background: The project "Antibiotic resistance in bacteria of animal origin – II" (ARBAO-II) was
funded by the European Union (FAIR5-QLK2-2002-01146) for the period 2003–05. The aim of this
project was to establish a program for the continuous monitoring of antimicrobial susceptibility of
pathogenic and indicator bacteria from food animals using validated and harmonised
methodologies. In this report the first data on the occurrence of antimicrobial resistance among
bacteria causing infections in pigs are reported.
Methods: Susceptibility data from 17,642 isolates of pathogens and indicator bacteria including
Actinobacillus pleuropneumoniae, Streptococcus suis and Escherichia coli isolated from pigs were
collected from fifteen European countries in 2002–2004.Results: Data for A. pleuropneumoniae from infected pigs were submitted from five countries. Most
of the isolates from Denmark were susceptible to all drugs tested with the exceptions of a low
frequency of resistance to tetracycline and trimethoprim – sulphonamide.
Data for S. suis were obtained from six countries. In general, a high level of resistance to
tetracycline (48.0 – 92.0%) and erythromycin (29.1 – 75.0%) was observed in all countries whereas
the level of resistance to ciprofloxacin and penicillin differed between the reporting countries.
Isolates from England (and Wales), France and The Netherlands were all susceptible to penicillin.
In contrast the proportion of strains resistant to ciprofloxacin ranged from 12.6 to 79.0% (2004)
and to penicillin from 8.1 – 13.0% (2004) in Poland and Portugal.
Data for E. coli from infected and healthy pigs were obtained from eleven countries. The data reveal
a high level of resistance to tetracyclines, streptomycin and ampicillin among infected pigs whereas
in healthy pigs the frequency of resistance was lower.
Conclusion: Bacterial resistance to some antimicrobials was frequent with different levels of
resistance being observed to several antimicrobial agents in different countries. The occurrence of
resistance varied distinctly between isolates from healthy and diseased pigs, with the isolates from
healthy pigs generally showing a lower level of resistance than those from diseased pigs.
The study suggests that the choice of antimicrobials used for the treatment of diseased animals
should preferably be based on knowledge of the local pattern of resistance
Prevalence of antimicrobial resistance among bacterial pathogens
Background: The project "Antibiotic resistance in bacteria of animal origin – II" (ARBAO-II) was
funded by the European Union (FAIR5-QLK2-2002-01146) for the period 2003–2005, with the aim
to establish a continuous monitoring of antimicrobial susceptibility among veterinary laboratories
in European countries based on validated and harmonised methodologies. Available summary data
of the susceptibility testing of the bacterial pathogens from the different laboratories were
collected.
Method: Antimicrobial susceptibility data for several bovine pathogens were obtained over a three
year period (2002–2004). Each year the participating laboratories were requested to fill in excelfile
templates with national summary data on the occurrence of antimicrobial resistance from
different bacterial species.
A proficiency test (EQAS – external quality assurance system) for antimicrobial susceptibility
testing was conducted each year to test the accuracy of antimicrobial susceptibility testing in the participating laboratories. The data from this testing demonstrated that for the species included in
the EQAS the results are comparable between countries.
Results: Data from 25,241 isolates were collected from 13 European countries. For Staphylococcus
aureus from bovine mastitis major differences were apparent in the occurrence of resistance
between countries and between the different antimicrobial agents tested. The highest frequency of
resistance was observed for penicillin. For Mannheimia haemolytica resistance to ampicillin,
tetracycline and trimethoprim/sulphonamide were observed in France, the Netherlands and
Portugal. All isolates of Pasteurella multocida isolated in Finland and most of those from Denmark,
England (and Wales), Italy and Sweden were susceptible to the majority of the antimicrobials.
Streptococcus dysgalactiae and Streptococcus uberis isolates from Sweden were fully susceptible. For
the other countries some resistance was observed to tetracycline, gentamicin and erythromycin.
More resistance and variation of the resistance levels between countries were observed for
Escherichia coli compared to the other bacterial species investigated.
Conclusion: In general, isolates from Denmark, England (and Wales), the Netherlands, Norway,
Sweden and Switzerland showed low frequencies of resistance, whereas many isolates from
Belgium, France, Italy, Latvia and Spain were resistant to most antimicrobials tested. In the future,
data on the prevalence of resistance should be used to develop guidelines for appropriate
antimicrobial use in veterinary medicine
Prevalence of antimicrobial resistance among bacterial pathogens isolated from cattle in different European countries: 2002–2004
Background: The project "Antibiotic resistance in bacteria of animal origin – II" (ARBAO-II) was
funded by the European Union (FAIR5-QLK2-2002-01146) for the period 2003–2005, with the aim
to establish a continuous monitoring of antimicrobial susceptibility among veterinary laboratories
in European countries based on validated and harmonised methodologies. Available summary data
of the susceptibility testing of the bacterial pathogens from the different laboratories were
collected.
Method: Antimicrobial susceptibility data for several bovine pathogens were obtained over a three
year period (2002–2004). Each year the participating laboratories were requested to fill in excelfile
templates with national summary data on the occurrence of antimicrobial resistance from
different bacterial species.
A proficiency test (EQAS – external quality assurance system) for antimicrobial susceptibility
testing was conducted each year to test the accuracy of antimicrobial susceptibility testing in the participating laboratories. The data from this testing demonstrated that for the species included in
the EQAS the results are comparable between countries.
Results: Data from 25,241 isolates were collected from 13 European countries. For Staphylococcus
aureus from bovine mastitis major differences were apparent in the occurrence of resistance
between countries and between the different antimicrobial agents tested. The highest frequency of
resistance was observed for penicillin. For Mannheimia haemolytica resistance to ampicillin,
tetracycline and trimethoprim/sulphonamide were observed in France, the Netherlands and
Portugal. All isolates of Pasteurella multocida isolated in Finland and most of those from Denmark,
England (and Wales), Italy and Sweden were susceptible to the majority of the antimicrobials.
Streptococcus dysgalactiae and Streptococcus uberis isolates from Sweden were fully susceptible. For
the other countries some resistance was observed to tetracycline, gentamicin and erythromycin.
More resistance and variation of the resistance levels between countries were observed for
Escherichia coli compared to the other bacterial species investigated.
Conclusion: In general, isolates from Denmark, England (and Wales), the Netherlands, Norway,
Sweden and Switzerland showed low frequencies of resistance, whereas many isolates from
Belgium, France, Italy, Latvia and Spain were resistant to most antimicrobials tested. In the future,
data on the prevalence of resistance should be used to develop guidelines for appropriate
antimicrobial use in veterinary medicine