750 research outputs found

    Socratic Proofs for Propositional Linear-Time Logic

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    This paper presents a calculus of Socratic proofs for Propositional Linear-Time Logic (PLTL) and discusses potential automation of its proof search

    Specification and verification of reconfiguration protocols in grid component systems

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    In this work we present an approach for the formal specification and verification of the reconfiguration protocols in Grid component systems. We consider Fractal, a modular and extensible component model. As a specification tool we invoke a specific temporal language, separated clausal normal form, which has been shown to be capable of expressing any ECTL+ expression thus, we are able to express the complex fairness properties of a component system. The structure of the normal enables us to directly apply the deductive verification technique, temporal resolution defined in the framework of branching-time temporal logic

    Poisson-Jacobi reduction of homogeneous tensors

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    The notion of homogeneous tensors is discussed. We show that there is a one-to-one correspondence between multivector fields on a manifold MM, homogeneous with respect to a vector field Δ\Delta on MM, and first-order polydifferential operators on a closed submanifold NN of codimension 1 such that Δ\Delta is transversal to NN. This correspondence relates the Schouten-Nijenhuis bracket of multivector fields on MM to the Schouten-Jacobi bracket of first-order polydifferential operators on NN and generalizes the Poissonization of Jacobi manifolds. Actually, it can be viewed as a super-Poissonization. This procedure of passing from a homogeneous multivector field to a first-order polydifferential operator can be also understood as a sort of reduction; in the standard case -- a half of a Poisson reduction. A dual version of the above correspondence yields in particular the correspondence between Δ\Delta-homogeneous symplectic structures on MM and contact structures on NN.Comment: 19 pages, minor corrections, final version to appear in J. Phys. A: Math. Ge

    Detection of a Specific Inhibitor of Interleukin 1 in Sera of UVB-Treated Mice

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    It was recently demonstrated that murine keratinocytes upon irradiation with ultraviolet (UV) light release an immunosuppressive cytokine which blocks the biological activity of interleukin 1 (IL 1). This epidermal cell derived inhibitor (EC-contra IL 1) exhibits a molecular weight of 40 kD and a pI of approximately 9.0. EC-contra IL 1 in vivo possibly may penetrate through the basal lamina and subsequently cause systemic immunosuppression following UV-exposure. In the present study, we tested whether EC-contra IL 1 can also be detected in vivo. Serum samples obtained from total body UV-exposed mice were subjected to HPLC gel filtration and tested for IL 1 inhibitory activity. While a non-specific high molecular weight (300 kD) suppressor factor was detected in sera of both UV-exposed and sham treated control mice, a specific IL 1 inhibitor exhibiting a molecular weight of 40 kD was observed only in sera of UV-exposed mice. This cytokine named serum-contra IL 1 was maximally released 24 h after UV-exposure, exhibited a pI of 9.0, and blocked the activity of natural as well as recombinant interleukin 1 in a dose dependent manner. Serum-contra IL 1 did not suppress interleukin 2 or interleukin 3 and did not inhibit spontaneous cell proliferation. The present biochemical and biologic data suggest that serum-contra IL 1 and EC-contra IL 1 appear to be closely related if not identical. These observations therefore indicate that keratinocytes upon UV-irradiation in vivo release EC-contra IL 1 which may at least partly be responsible for the immunosuppression following UV-exposure
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