Edukasi Penyimpanan dan Pembuangan Obat Rusak/ Expire date dalam Keluarga

Pengetahuan masyarakat mengenai dunia kesehatan, terutama obat masih sangat terbatas, padahal obat merupakan bahan yang mudah kita temukan di sekitar kita. Obat harus selalu digunakan secara benar agar memberikan manfaat klinik yang optimal. Pada kegiatan ini dilakukanEdukasi dalam bentuk penyuluhan tentang Penyimpanan dan Pembuangan Obat Rusak/ Expire date dalam Keluarga di Desa Buata. Penyimpanan dan pembuangan obat merupakan suatu masalah penting di Indonesia. Dalam skala rumah tangga, penyimpanan obat yang kurang baik dapat menyebabkan permasalahan serius, seperti keracunan obat secara tidak sengaja. Selain itu, pembuangan atau pemusnahan obat yang kurang benar selanjutnya memunculkan potensi terjadinya daur ulang illegal kemasan atau produk obat kadaluarsa. Metode yang dipakai dalam mencapai tujuan tersebut adalah kegiatan sosialisasi atau edukasi yaitu dengan menjelaskan materi kepada masyarakat dan melakukan pembagian leafleat tentang cara penyimpanan obat dan cara membuang obat dengan baik dan benar.  Pada kegiatan Edukasi tentang cara penyimpanan obat yang baik dan benar akan membahas materi tentang obat, jenis jenis obat, Kemudian penjelasan sediaan obat dan cara penggunaannya, perlu perhatian khusus agar tidak salah dalam menggunakannya serta tata cara penyimpanan dan pembuangan obat yang baik dan benar berdasarkan bentuk sediaan obat

AICER Es Krim Daun Kelor sebagai Pencegah Stunting di Desa Bongoime, Kec. Tilongkabila. Bone Bolango

Desa  Bongoime,  Kecamatan  Tilongkabila,  Kabupaten  Bone Bolango merupakan   salah   satu   desa   lokasi terpilih untuk dilakukan pengabdian KKN PK.   Di   desa   ini   masyarakat   sudah memiliki  pengetahuan  kesehatan  yang  memadai.  Angka stunting di  desa Bongoime  menurut  data  Puskesmas  setempat  adalah 10% dalam  tiga  tahun terakhir,  namun  masyarakat desa  ini  belum  memperhatikan  masalah  asupan gizi.  Oleh  karena  itu  daun  kelor  (Moringa  oleifera Lam.)  sebagai  sumberdaya tumbuhan  yang  cukup  mudah  dijumpai  di  wilayah  Bone Bolango dapat  menjadi  bahan baku  produk  inovasi  dalam  pencegahan stunting dan  pemenuhan  gizi  ibu hamil  dan  anak-anak.  Daun  kelor  yang  diolah  menjadi  es  krim  mengandung zat  gizi  yang  tinggi,  terutama protein  dan  kalsium.  Mitra  kegiatan  ini  adalah maayarakat Desa Bongoime.   Pengolahan   produk   inovasi   es   krim   kelor dilaksanakan  melalui  beberapa  metode,yaitu:  (1)  sosialisasi mengenai mater stunting; (2) pelatihan  produksi;  (3) pendampingan produksi. Secara umum kegiatan ini cukup baik  dalam  membantu  permasalahan  yang  dihadapi  mitra,  yaitu  memenuhi asupan  gizi  sehingga  terhindar  dari  permasalahan stunting.Hal  positif  lain yangdiperoleh  adalah  adanya  diversifikasi  pangan  berbahan  dasar  daun kelor

POTENSI EKSTRAK ETANOL KULIT BUAH MATOA (Pometia pinnata J.R Forst & G.Forst) TERHADAP BAKTERI PENYEBAB KARIES GIGI

One of the infectious diseases that occur in the oral cavity is dental caries (cavities). The bacteria that play a role in the occurrence of infection are Streptococcus mutans bacteria, and the matoa plant is one of the plants that can act as antibacterial (Pometia pinnata J.R Forst) which has high efficacious compounds. This study aimed to determine the activity and potency of the ethanolic extract of matoa fruit peel (Pometia pinnata J.R Forst & G. Forst) against Streptococcus mutans bacteria. This research is a laboratory experimental research. Matoa fruit peel simplicia was extracted by maceration method with 96% ethanol solvent, then tested for phytochemical screening to determine the class of compounds contained in the matoa fruit peel. Furthermore, the activity was tested against Streptococcus mutans bacteria using a positive control of chloramphenicol antibiotics and a negative control of Dimethyl Sulfoxide. After that, the values of the Minimum Inhibitory Level and Minimum Killer were measured. From these results, it was continued to test the antibacterial potential using the Kirby Bauer method. The results showed that the ethanol extract of matoa fruit peel (Pometia pinnata J.R Forst & G. Forst) had activity against Streptococcus mutans bacteria. The potential value of the matoa fruit peel extract against Streptococcus mutans bacteria at concentrations of 25%, 50% and 75%, respectively, was 11.75 mm, 15.82 mm and 18.75 mm which was included in the category of strong inhibition

Penetapan kadar Nipagin (Methyl Paraben) pada body lotion yang beredar di Kota Gorontalo secara Spektrofotometri UV-Vis

Body lotion is a skincare cosmetics products that usually contain preservatives as inhibitors of bacteria and fungi growth. According to the Food and Drug Supervisory Agency of Indonesian Republic, 2011: HK.03.1.23.08.11.07517, in which the preservative levels of nipagin (methyl paraben) in a body lotion must be 0.4%, Preservative level over 0.4% may result in skin irritation and allergic reactions. The purpose of this study was to determine the nipagin’s essence and levels in body lotions sold in Gorontalo City. Nipagin’s identification was carried out with a qualitative analysis using Thin Layer Chromatography and color change using 2% of deniges reactor and sodium nitrite, while the quantitative analysis was carried out with spectrophotometry UV-Vis at 258 nm wavelength that was previously extracted with 96% of ethanol solvent. The results of the qualitative study show that four (A, D, E, and F) out of six samples of body lotions: A, B, C, D, E, and F contained preservatives. Quantitatively, the levels of nipagin) on the four samples are sequentially shown as follows: by A:0.38%, D:0.04%, E:0.14%, F:0.14%. All in all, the samples are entirely eligible according to the Regulotions of the National Agency of Drug and Food of Indonesian Republic 2011: HK.03.1.23.08.11.07517

Profil Kesesuaian Terapi Obat Pada Pasien Dispepsia di Ruangan IGD RSUD dr. Zainal Umar Sidiki

Dyspepsia is an upper gastrointestinal symptom complex that has symptoms of fulllness after eating, early satiety, or epigastric pain of burning without any sturctural cause. The research aims to determine the suitability of drug therapy based on the right patient, the right drug, and the right dose in the emergency room at dr. Zainal Umar Sidiki Regional Public Hospital, North Gorontalo Regency. This research is descriptive research with retrospective data collection. The data used were obtained from medical records of patients in the ER, with 215 patients whose paatient characteristics were processed using the Microsoft Excel program. The results showed that most dyspepsia patients were female, namely 124 (58%), the age range 50-60 years was 74 (34%). The most widely used therapy is combination therapy 154 (72%). The largest variation in the number of single drug uses Inj. Omeprazole amounted to 34 (16%), and a combination of two types of drugs that are widely used, namely Inj. Omeprazole with Inj. Ondansetron has a total of 36 (17%) and a combination of three types of drugs that are widely use, including PPIs, cytoprotectants, and prokinetics, totaling 23 (11%). The rationality of the right patient treatment was 53,48%, the right medicstion was 78%, and the right dose was 100%. In conclusionm the appropriateness of therapy based on the right patient was 53,48%, the right drug was 78%, and the right dose was 100%

Identifikasi Senyawa Metabolit Sekunder Daun Spigelia anthelmia L. dan Uji Aktifitas Antioksidan Menggunakan Metode DPPH (1,1-Diphenyl-2-Picrylhidrazy)

Spigelia anthelmia is a type of weed plant that is classified as toxic and is included in the list of herb of medicine. The research aims to determine the secondary metabolite content of Spigelia anthelmia L. leaves extract and antioxidant activity test using the DPPH (1,1-Diphenyl-2-Picrylhydrazy) method. The research samples are extracted by applying the total maceration method with methanol as a solvent and followed by partition method using n-hexane, ethyl acetate, and methanol as solvents. The identification of flavonoid compounds content is performed by employing Thin Layer Chromatography method with methanol as eluent: n-hexane (1:4), ethyl acetate:n-hexane (4:1), ethyl acetate:n-hexane (4:1). Meanwhile, the antioxidant activity test is performed by employing UV-Vis Spectrophotometry method. The result of identification by thin layer chromatography using AlCl3 spray reagent, Lieberman Burchard. Dragendrof, and cerium sulfate, indicate that the Spigelia anthelmia L. leaves extract contains alkaloids, flavonoids, and terpenoids. In addition, the antioxidant activity test of Spigelia anthelmia L. leaves extract is carried out at wavelength of UV 516 nm with an absorbance value of 0,654 A. with a linear equation of y = 0,027 x – 42,83 with a correlation coefficient (R2) = 0,0983 and has the strongest IC50 at the methanol fraction for 7,69 µg/ml

ANTIBIOFILM ACTIVITY OF MANGOSTEEN (Garcinia mangostana L.) LEAF EXTRACT AGAINST COLLECTION OF BACTERIAL ISOLATES FROM DIABETIC ULCERS

Mangosteen (Garcinia mangostana L.) is a plant that contains many benefits and has the potential to be a medicinal plant in treating various diseases. Mangosteen leaves contain flavonoids, saponins, tannins, alkaloids and terpenoids which are known to have antibacterial and antibiofilm properties. This anti-biofilm agent is an alternative treatment for diabetic wound infections where cases of antibiotic resistance have increased. One of the causes of resistance is the biofilm formed by infectious bacteria. This research is a type of laboratory experimental research which aims to determine the anti-biofilm activity of mangosteen leaf extract against biofilms formed by a collection of bacterial isolates from diabetic wounds. The antibiofilm activity test carried out consisted of a cell attachment prevention test, a biofilm formation inhibition test, and a biofilm destruction test using the crystal violet staining method using the tube method and measuring optical density values ​​on a UV-Vis spectrophotometer. The concentrations of mangosteen leaf extract used are 60%, 80% and 100% as well as control – and control +. The results of the antibiofilm test showed that mangosteen leaf extract had the best activity in inhibiting biofilm formation, preventing cell attachment, and destroying biofilm, respectively. The three most optimal activities were found at a concentration of 100%, with an inhibition percentage of 50.51%, prevention of 32.56%, and destruction of 5.63%